Search Results - "Wood, Thomas Ragnar"
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Hypothermia Is Neuroprotective after Severe Hypoxic-Ischaemic Brain Injury in Neonatal Rats Pre-Exposed to PAM3CSK4
Published in Developmental neuroscience (2018)“…Preclinical research on the neuroprotective effect of hypothermia (HT) after perinatal asphyxia has shown variable results, depending on comorbidities and…”
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Observational study comparing heart rate in crying and non-crying but breathing infants at birth
Published in BMJ paediatrics open (01-04-2023)“…BackgroundStimulating infants to elicit a cry at birth is common but could result in unnecessary handling. We evaluated heart rate in infants who were crying…”
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Treatment temperature and insult severity influence the neuroprotective effects of therapeutic hypothermia
Published in Scientific reports (21-03-2016)“…Therapeutic hypothermia (HT) is standard care for moderate and severe neonatal hypoxic-ischaemic encephalopathy (HIE), the leading cause of permanent brain…”
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Hypothermic Neuronal Rescue from Infection-Sensitised Hypoxic-Ischaemic Brain Injury Is Pathogen Dependent
Published in Developmental neuroscience (01-01-2017)“…Perinatal infection increases the vulnerability of the neonatal brain to hypoxic-ischaemic (HI) injury. Hypothermia treatment (HT) does not provide…”
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Variability and sex-dependence of hypothermic neuroprotection in a rat model of neonatal hypoxic–ischaemic brain injury: a single laboratory meta-analysis
Published in Scientific reports (02-07-2020)“…Therapeutic hypothermia (HT) is standard care for term infants with hypoxic–ischaemic (HI) encephalopathy. However, the efficacy of HT in preclinical models,…”
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Increased risk of bradycardia in vigorous infants receiving early as compared to delayed cord clamping at birth
Published in Journal of perinatology (01-06-2023)“…Objective To compare HR pattern of vigorous newborns during the first 180 s with early (≤60 s, ECC) or delayed (>60 s, DCC) cord clamping. Study design…”
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Restraint stress during neonatal hypoxia‐ischemia alters brain injury following normothermia and hypothermia
Published in Physiological reports (01-01-2023)“…Rodent models of neonatal hypoxic–ischemic (HI) injury require a subset of animals to be immobilized for continuous temperature monitoring during the insult…”
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Xenon depresses aEEG background voltage activity whilst maintaining cardiovascular stability in sedated healthy newborn pigs
Published in Journal of the neurological sciences (15-04-2016)“…Abstract Background Changes in electroencephalography (EEG) voltage range are used to monitor the depth of anaesthesia, as well as predict outcome after…”
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Monitoring of cerebral blood flow during hypoxia‐ischemia and resuscitation in the neonatal rat using laser speckle imaging
Published in Physiological reports (01-04-2016)“…Neonatal hypoxic‐ischemic encephalopathy (HIE) is associated with alterations in cerebral blood flow (CBF) as a result of perinatal asphyxia. The extent to…”
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