Search Results - "Wood, T L"

Gender-Specific Changes in Bone Turnover and Skeletal Architecture in Igfbp-2-Null Mice by DeMambro, V. E, Clemmons, D. R, Horton, L. G, Bouxsein, M. L, Wood, T. L, Beamer, W. G, Canalis, E, Rosen, C. J

“…IGF-binding protein-2 (IGFBP-2) is a 36-kDa protein that binds to the IGFs with high affinity. To determine its role in bone turnover, we compared Igfbp2−/−…”
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Genomic and Biochemical Characterization of Acinetobacter Podophage Petty Reveals a Novel Lysis Mechanism and Tail-Associated Depolymerase Activity by Hernandez-Morales, A C, Lessor, L L, Wood, T L, Migl, D, Mijalis, E M, Cahill, J, Russell, W K, Young, R F, Gill, J J

“…The increased prevalence of drug-resistant, nosocomial infections, particularly from pathogenic members of the complex, necessitates the exploration of novel…”
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Gene-targeting and transgenic approaches to IGF and IGF binding protein function by Wood, T L

“…The ability to manipulate genetic information in the germ line of mice has provided powerful approaches to study gene function in vivo. These approaches have…”
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The insulin-like growth factors (IGFs) and IGF binding proteins in postnatal development of murine mammary glands by Wood, T L, Richert, M M, Stull, M A, Allar, M A

“…The insulin-like growth factors are mitogens and survival factors for normal mammary epithelial cells in vitro. Data reviewed here demonstrate that mRNAs for…”
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Acute exposure to CNTF in vivo induces multiple components of reactive gliosis by LEVISON, S. W, DUCCESCHI, M. H, YOUNG, G. M, WOOD, T. L

“…CNS trauma or disease induces a constellation of changes in the glia comprising the condition known as reactive gliosis. At present, little is known regarding…”
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Distinct expression patterns of insulin-like growth factor binding proteins 2 and 5 during fetal and postnatal development by Green, B N, Jones, S B, Streck, R D, Wood, T L, Rotwein, P, Pintar, J E

“…Insulin-like growth factors (IGFs), when isolated from serum or tissue fluids, are usually found as part of a protein complex which also contains one of…”
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Stimulation of tumor growth by recombinant human insulin-like growth factor-I (IGF-I) is dependent on the dose and the level of IGF-I receptor expression by BUTLER, A. A, BLAKESLEY, V. A, TSOKOS, M, POULIKI, V, WOOD, T. L, LEROITH, D

“…The insulin-like growth factors (IGF) I and II regulate metabolism, mitogenesis, differentiation, and apoptosis. The therapeutic uses of IGF-I have been…”
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Expression of the gene for the neuronal intermediate filament protein alpha-internexin coincides with the onset of neuronal differentiation in the developing rat nervous system by Fliegner, K H, Kaplan, M P, Wood, T L, Pintar, J E, Liem, R K

“…While neurofilaments have long been considered early markers of neuronal differentiation, they cannot be detected in most newly postmitotic neurons of the…”
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An ellipsometric method for the determination of the dielectric tensor of an optically uniaxial material suited for in-situ measurements by Xu, W., Wood, L.T., Golding, T.D.

“…We introduce a photometric ellipsometric method to determine the dielectric tensor of an optically uniaxial material suited for in-situ measurements. The…”
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Optimization of conventional ellipsometric setups for determining the dielectric tensor of arbitrarily anisotropic systems by Xu, W., Wood, L.T., Golding, T.D.

“…We present a general theoretical development to optimize the setup of a conventional ellipsometer to determine dielectric tensors of arbitrarily anisotropic…”
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Insulin-like Growth Factor I, but Not Neurotrophin-3, Sustains Akt Activation and Provides Long-Term Protection of Immature Oligodendrocytes from Glutamate-Mediated Apoptosis by Ness, Jennifer K., Wood, Teresa L.

“…Glutamate toxicity is a major contributor to death of oligodendroglia in diverse CNS disorders. The goal of these studies was to investigate the mechanisms of…”
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IGF-I and microglia/macrophage proliferation in the ischemic mouse brain by O'Donnell, Steven L., Frederick, Terra J., Krady, J. Kyle, Vannucci, Susan J., Wood, Teresa L.

“…We have used a model of hypoxic‐ischemic brain injury in adult male C57BL/6 mice to study insulin‐like growth factor‐I (IGF‐I) and IGF‐binding protein (IGFBP)…”
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The expression pattern of an insulin-like growth factor (IGF)-binding protein gene is distinct from IGF-II in the midgestational rat embryo by Wood, T L, Brown, A L, Rechler, M M, Pintar, J E

“…Insulin-like growth factor-II (IGF-II), the predominant form of IGF in fetal and neonatal serum and tissues, is found in vivo complexed with IGF-binding…”
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IGF-I Synergizes with FGF-2 to Stimulate Oligodendrocyte Progenitor Entry into the Cell Cycle by Jiang, Fengjun, Frederick, Terra J., Wood, Teresa L.

“…Secreted peptide growth factors are critical extracellular signals that interact to promote the proliferation, differentiation, and survival of progenitor…”
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The insulin-like growth factors (IGF) and IGF type I receptor during postnatal growth of the murine mammary gland: sites of messenger ribonucleic acid expression and potential functions by Richert, M M, Wood, T L

“…The goals of this study were to determine the cellular sites of insulin-like growth factor (IGF) and IGF type-I receptor (IGF-IR) expression and to begin to…”
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IGFs and IGFBPs in the normal mammary gland and in breast cancer by Wood, Teresa L, Yee, Douglas

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Experimental Stroke in the Female Diabetic, db/db, Mouse by Vannucci, Susan J., Willing, Lisa B., Goto, Shozo, Alkayed, Nabil J., Brucklacher, Robert M., Wood, Teresa L., Towfighi, Javad, Hurn, Patricia D., Simpson, Ian A.

“…Diabetic hyperglycemia increases brain damage after cerebral ischemia in animals and humans, although the underlying mechanisms remain unclear. Gender-linked…”
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Selective Alterations in Organ Sizes in Mice with a Targeted Disruption of the Insulin-Like Growth Factor Binding Protein-2 Gene by Wood, Teresa L, Rogler, Leslie E, Czick, Maureen E, Schuller, Alwin G.P, Pintar, John E

“…Insulin-like growth factor binding protein 2 (IGFBP-2) is one member of the family of IGF binding proteins believed to have both endocrine functions elicited…”
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Perinatal hypoxia-ischemia induces apoptotic and excitotoxic death of periventricular white matter oligodendrocyte progenitors by Ness, J K, Romanko, M J, Rothstein, R P, Wood, T L, Levison, S W

“…Hypoxia-ischemia (HI) is a leading cause of white matter damage, a major contributor to cerebral palsy in premature infants. Preferential white matter damage…”
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Altered pituitary growth hormone (GH) regulation in streptozotocin-diabetic rats: a combined defect of hypothalamic somatostatin and GH-releasing factor by Olchovsky, D, Bruno, J F, Wood, T L, Gelato, M C, Leidy, Jr, J W, Gilbert, Jr, J M, Berelowitz, M

“…Diabetes mellitus in the rat is associated with loss of pulsatile GH secretion. An interplay between hypothalamic GH-releasing factor (GRF) and inhibitory…”
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