Search Results - "Wood, Susan A"

Hypothalamic-Pituitary-Adrenal Axis Activation in Obstructive Sleep Apnea: The Effect of Continuous Positive Airway Pressure Therapy by Henley, David E., Russell, Georgina M., Douthwaite, Jennie A., Wood, Susan A., Buchanan, Fiona, Gibson, Rosemary, Woltersdorf, Wolfram W., Catterall, James R., Lightman, Stafford L.

“…Context: Obstructive sleep apnea (OSA) is a common condition with significant cardiovascular and metabolic comorbidity. We hypothesized that these may result…”
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The significance of glucocorticoid pulsatility by Lightman, Stafford L., Wiles, Crispin C., Atkinson, Helen C., Henley, David E., Russell, Georgina M., Leendertz, Jack A., McKenna, Mervyn A., Spiga, Francesca, Wood, Susan A., Conway-Campbell, Becky L.

“…Glucocorticoids are secreted in discrete pulses resulting in an ultradian rhythm in all species that have been studied. In the rat there is an approximately…”
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Rapid glucocorticoid receptor-mediated inhibition of hypothalamic-pituitary-adrenal ultradian activity in healthy males by Russell, Georgina M, Henley, David E, Leendertz, Jack, Douthwaite, Jennie A, Wood, Susan A, Stevens, Adam, Woltersdorf, Wolfram W, Peeters, Bernard W M M, Ruigt, Ge S F, White, Anne, Veldhuis, Johannes D, Lightman, Stafford L

“…A complex dynamic ultradian rhythm underlies the hypothalamic-pituitary-adrenal (HPA) circadian rhythm. We have investigated in normal human male subjects the…”
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Adaptive Changes in Basal and Stress-Induced HPA Activity in Lactating and Post-Lactating Female Rats by Windle, Richard J, Wood, Susan A, Kershaw, Yvonne M, Lightman, Stafford L, Ingram, Colin D

“…Lactation represents a period of marked adaptation of the hypothalamo–pituitary–adrenal HPA axis. We characterized basal and stress-induced HPA activity during…”
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Gonadal Steroid Modulation of Stress-Induced Hypothalamo-Pituitary-Adrenal Activity and Anxiety Behavior: Role of Central Oxytocin by Windle, Richard J, Gamble, Lisa E, Kershaw, Yvonne M, Wood, Susan A, Lightman, Stafford L, Ingram, Colin D

“…Intracerebroventricular administration of oxytocin reduces anxiety behavior and hypothalamo-pituitary-adrenal (HPA) responses to stress in female rats. Similar…”
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Plasma apelin levels in obstructive sleep apnea and the effect of continuous positive airway pressure therapy by Henley, David E, Buchanan, Fiona, Gibson, Rosemary, Douthwaite, Jennie A, Wood, Susan A, Woltersdorf, Wolfram W, Catterall, James R, Lightman, Stafford L

“…Apelin is a peptide hormone with cardiovascular and glucose homeostasis properties, and obstructive sleep apnea (OSA) is complicated by cardiovascular and…”
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Effect of the glucocorticoid receptor antagonist Org 34850 on fast and delayed feedback of corticosterone release by Spiga, Francesca, Harrison, Louise R, Wood, Susan A, MacSweeney, Cliona P, Thomson, Fiona J, Craighead, Mark, Grassie, Morag, Lightman, Stafford L

“…We investigated the effect of the glucocorticoid receptor (GR) antagonist Org 34850 on fast and delayed inhibition of corticosterone secretion in response to…”
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Oxytocin Attenuates Stress-Induced c-fos mRNA Expression in Specific Forebrain Regions Associated with Modulation of Hypothalamo-Pituitary-Adrenal Activity by Windle, Richard J, Kershaw, Yvonne M, Shanks, Nola, Wood, Susan A, Lightman, Stafford L, Ingram, Colin D

“…We reported previously that the neuropeptide oxytocin attenuates stress-induced hypothalamo-pituitary-adrenal (HPA) activity and anxiety behavior. This study…”
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Regulation of the Hypothalamic-Pituitary-Adrenal Axis Circadian Rhythm by Endocannabinoids Is Sexually Diergic by Atkinson, Helen C, Leggett, James D, Wood, Susan A, Castrique, Emma S, Kershaw, Yvonne M, Lightman, Stafford L

“…We have examined the effects of acute administration of the cannabinoid receptor type 1 (CB1) antagonist AM251 on the rat hypothalamic-pituitary-adrenal (HPA)…”
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Acute Glucocorticoid Administration Rapidly Suppresses Basal and Stress-Induced Hypothalamo-Pituitary-Adrenal Axis Activity by Andrews, Marcus H, Wood, Susan A, Windle, Richard J, Lightman, Stafford L, Ingram, Colin D

“…Hypothalamo-pituitary-adrenal (HPA) axis activity is subject to negative feedback control by glucocorticoids. Although the rapid component of this feedback is…”
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Potential contribution of computer-aided detection to the sensitivity of screening mammography by Warren Burhenne, L J, Wood, S A, D'Orsi, C J, Feig, S A, Kopans, D B, O'Shaughnessy, K F, Sickles, E A, Tabar, L, Vyborny, C J, Castellino, R A

“…To determine the false-negative rate in screening mammography, the capability of computer-aided detection (CAD) to identify these missed lesions, and whether…”
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Corticosteroids mediate fast feedback of the rat hypothalamic-pituitary-adrenal axis via the mineralocorticoid receptor by Atkinson, Helen C, Wood, Susan A, Castrique, Emma S, Kershaw, Yvonne M, Wiles, Crispin C R, Lightman, Stafford L

“…The aim of this study was to investigate fast corticosteroid feedback of the hypothalamic-pituitary-adrenal (HPA) axis under basal conditions, in particular…”
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Redesigning an FKBP-Ligand Interface to Generate Chemical Dimerizers with Novel Specificity by Clackson, Tim, Yang, Wu, Rozamus, Leonard W., Hatada, Marcos, Amara, Jane F., Rollins, Carl T., Stevenson, Lauren F., Magari, Shannon R., Wood, Susan A., Courage, Nancy L., Lu, Xiaode, Cerasoli, Franklin, Gilman, Michael, Holt, Dennis A.

“…FKBP ligand homodimers can be used to activate signaling events inside cells and animals that have been engineered to express fusions between appropriate…”
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Pulmonary Embolism: Computer-aided Detection at Multidetector Row Spiral Computed Tomography by Schoepf, U Joseph, Schneider, Alex C, Das, Marco, Wood, Susan A, Cheema, Jugesh I, Costello, Philip

“…BACKGROUNDWe aimed to evaluate the feasibility and performance of a computer-aided detection (CAD) tool for automated detection of segmental and subsegmental…”
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Reduced stress responsiveness in pregnancy: Relationship with pattern of forebrain c- fos mRNA expression by Windle, Richard J, Wood, Susan A, Kershaw, Yvonne M, Lightman, Stafford L, Ingram, Colin D

“…Abstract Stress-induced activation of the hypothalamo-pituitary-adrenal (HPA) axis is known to be attenuated during late pregnancy and throughout lactation. To…”
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Computer-aided diagnosis as a second reader: spectrum of findings in CT studies of the chest interpreted as normal by Peldschus, Kersten, Herzog, Peter, Wood, Susan A, Cheema, Jugesh I, Costello, Philip, Schoepf, U Joseph

“…To assess the performance of an automated computer-aided detection (CAD) system as a second reader on chest CT studies interpreted as normal at routine…”
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Fluoxetine inhibits corticotropin-releasing factor (CRF)-induced behavioural responses in rats by Lowry, Christopher A, Hale, Matthew W, Plant, Andrea, Windle, Richard J, Shanks, Nola, Wood, Susan A, Ingram, Colin D, Renner, Kenneth J, Lightman, Stafford L, Summers, Cliff H

“…Corticotropin-releasing factor (CRF) is a potent neuromodulator of stress-related behaviour but the neural mechanisms underlying these effects are not clear…”
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Scaling Up: Initiatives to Support Retention by Wood, Susan A.

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A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation by Barr, R Graham, Berkowitz, Eugene A, Bigazzi, Francesca, Bode, Frederick, Bon, Jessica, Bowler, Russell P, Chiles, Caroline, Crapo, James D, Criner, Gerard J, Curtis, Jeffrey L, Dass, Chandra, Dirksen, Asger, Dransfield, Mark T, Edula, Goutham, Erikkson, Leif, Friedlander, Adam, Galperin-Aizenberg, Maya, Gefter, Warren B, Gierada, David S, Grenier, Philippe A, Goldin, Jonathan, Han, MeiLan K, Hanania, Nicola A, Hansel, Nadia N, Jacobson, Francine L, Kauczor, Hans-Ulrich, Kinnula, Vuokko L, Lipson, David A, Lynch, David A, MacNee, William, Make, Barry J, Mamary, A James, Mann, Howard, Marchetti, Nathaniel, Mascalchi, Mario, McLennan, Geoffrey, Murphy, James R, Naidich, David, Nath, Hrudaya, Newell, Jr, John D, Pistolesi, Massimo, Regan, Elizabeth A, Reilly, John J, Sandhaus, Robert, Schroeder, Joyce D, Sciurba, Frank, Shaker, Saher, Sharafkhaneh, Amir, Silverman, Edwin K, Steiner, Robert M, Strange, Charlton, Sverzellati, Nicola, Tashjian, Joseph H, van Beek, Edwin J R, Washington, Lacey, Washko, George R, Westney, Gloria, Wood, Susan A, Woodruff, Prescott G

“…The purposes of this study were: to describe chest CT findings in normal non-smoking controls and cigarette smokers with and without COPD; to compare the…”
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Computer-aided detection for mammography: improved algorithm performance with operator determined points characterized by new metrics by Zeng, Xiaolan, Medeiros, Sarah, Wood, Susan A, Stapleton, Sandra, Roehrig, Jimmy, O'Shaughnessy, Kathryn, Castellino, Ronald A

“…Recent prospective studies have suggested that user's confidence in computer-aided detection (CAD) marks and their tolerance of false positive (FP) marks play…”
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