Search Results - "Wood, Kaitlin M."

Defining substrate requirements for cleavage of farnesylated prelamin A by the integral membrane zinc metalloprotease ZMPSTE24 by Wood, Kaitlin M, Spear, Eric D, Mossberg, Otto W, Odinammadu, Kamsi O, Xu, Wenxin, Michaelis, Susan

“…The integral membrane zinc metalloprotease ZMPSTE24 plays a key role in the proteolytic processing of farnesylated prelamin A, the precursor of the nuclear…”
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Cofactor Complexes of DesD, a Model Enzyme in the Virulence-related NIS Synthetase Family by Hoffmann, Katherine M, Goncuian, Eliana S, Karimi, Kimya L, Amendola, Caroline R, Mojab, Yasi, Wood, Kaitlin M, Prussia, Gregory A, Nix, Jay, Yamamoto, Margaret, Lathan, Kiera, Orion, Iris W

“…The understudied nonribosomal-peptide-synthetase-independent siderophore (NIS) synthetase family has been increasingly associated with virulence in bacterial…”
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A humanized yeast system to analyze cleavage of prelamin A by ZMPSTE24 by Spear, Eric D., Alford, Rebecca F., Babatz, Tim D., Wood, Kaitlin M., Mossberg, Otto W., Odinammadu, Kamsi, Shilagardi, Khurts, Gray, Jeffrey J., Michaelis, Susan

“…•The protease ZMPSTE24 performs the final cleavage step in prelamin A maturation.•Mutations in ZMPSTE24 or LMNA cause progeria and related disorders.•A…”
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Surface histidine mutations for the metal affinity purification of a β-carbonic anhydrase by Hoffmann, Katherine M., Wood, Kaitlin M., Labrum, Alysha D., Lee, Dave K., Bolinger, Ingmar M., Konis, Mary E., Blount, Adam G., Prussia, Gregory A., Schroll, Monica M., Watson, Jeffrey M.

“…Metal affinity chromatography using polyhistidine tags is a standard laboratory technique for the general purification of proteins from cellular systems, but…”
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