Search Results - "Wood, Jennifer R"
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1
MicroRNAs are absorbed in biologically meaningful amounts from nutritionally relevant doses of cow milk and affect gene expression in peripheral blood mononuclear cells, HEK-293 kidney cell cultures, and mouse livers
Published in The Journal of nutrition (01-10-2014)“…MicroRNAs (miRNAs) regulate genes in animals and plants and can be synthesized endogenously. In milk, miRNAs are encapsulated in exosomes, thereby conferring…”
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2
Yes-associated protein 1 is required for proliferation and function of bovine granulosa cells in vitro
Published in Biology of reproduction (21-11-2019)“…Yes-associated protein 1 (YAP1) is a major component of the Hippo signaling pathway. Although the exact extracellular signals that control the Hippo pathway…”
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3
Using Single Molecule mRNA Fluorescent in Situ Hybridization (RNA-FISH) to Quantify mRNAs in Individual Murine Oocytes and Embryos
Published in Scientific reports (21-05-2018)“…Changes in abundance of mRNAs during oocyte growth and maturation and during pre-implantation embryo development have been documented using quantitative…”
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4
Palmitate induces integrated stress response and lipoapoptosis in trophoblasts
Published in Cell death & disease (11-01-2024)“…Maternal obesity increases the risk of childhood obesity and programs the offspring to develop metabolic syndrome later in their life. Palmitate is the…”
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5
Formation and characterization of lipid droplets of the bovine corpus luteum
Published in Scientific reports (09-07-2020)“…Establishment and maintenance of pregnancy depends on progesterone synthesized by luteal tissue in the ovary. Our objective was to identify the characteristics…”
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6
Obesity induces ovarian inflammation and reduces oocyte quality
Published in Reproduction (Cambridge, England) (01-09-2019)“…In the United States, 36.5% of women between the ages of 20 and 39 years are obese. This obesity results in not only metabolic disorders including type II…”
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Altered theca and cumulus oocyte complex gene expression, follicular arrest and reduced fertility in cows with dominant follicle follicular fluid androgen excess
Published in PloS one (16-10-2014)“…Aspiration of bovine follicles 12-36 hours after induced corpus luteum lysis serendipitously identified two populations of cows, one with High androstenedione…”
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8
Identification of Lipids and Cytokines in Plasma and Follicular Fluid before and after Follicle-Stimulating Hormone Stimulation as Potential Markers for Follicular Maturation in Cattle
Published in Animals (Basel) (01-10-2023)“…The process of follicle maturation leading to ovulation is a key milestone in female fertility. It is known that circulating lipids and cytokines play a role…”
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Protein Kinase A and 5' AMP-Activated Protein Kinase Signaling Pathways Exert Opposite Effects on Induction of Autophagy in Luteal Cells
Published in Frontiers in cell and developmental biology (08-11-2021)“…In the absence of pregnancy the ovarian corpus luteum undergoes regression, a process characterized by decreased production of progesterone and structural…”
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The Molecular Phenotype of Polycystic Ovary Syndrome (PCOS) Theca Cells and New Candidate PCOS Genes Defined by Microarray Analysis
Published in The Journal of biological chemistry (18-07-2003)“…Polycystic ovary syndrome (PCOS) affects 5% of reproductive aged women and is the leading cause of anovulatory infertility. A hallmark of PCOS is excessive…”
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Transcriptomic data of bovine ovarian granulosa cells of control and High A4 cows
Published in Data in brief (01-08-2021)“…Microarray analysis using Affymetrix Bovine GeneChip 1.0 ST Array to determine RNA expression analysis was performed on somatic granulosa cells from two…”
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Valproate Potentiates Androgen Biosynthesis in Human Ovarian Theca Cells
Published in Endocrinology (Philadelphia) (01-02-2004)“…In patients with epilepsy, treatment with valproate (VPA) has been reported to be associated with polycystic ovary syndrome-like symptoms including weight…”
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13
Allosteric Modulation of Estrogen Receptor Conformation by Different Estrogen Response Elements
Published in Molecular endocrinology (Baltimore, Md.) (01-07-2001)“…Estrogen-regulated gene expression is dependent on interaction of the estrogen receptor (ER) with the estrogen response element (ERE). We assessed the ability…”
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Transcriptomic and bioinformatics analysis of the early time-course of the response to prostaglandin F2 alpha in the bovine corpus luteum
Published in Data in brief (01-10-2017)“…RNA expression analysis was performed on the corpus luteum tissue at five time points after prostaglandin F2 alpha treatment of midcycle cows using an…”
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Transcriptomes of bovine ovarian follicular and luteal cells
Published in Data in brief (01-02-2017)“…Affymetrix Bovine GeneChip® Gene 1.0 ST Array RNA expression analysis was performed on four somatic ovarian cell types: the granulosa cells (GCs) and theca…”
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Unraveling the role of lipid droplets and perilipin 2 in bovine luteal cells
Published in The FASEB journal (15-06-2024)“…Steroidogenic tissues contain cytosolic lipid droplets that are important for steroidogenesis. Perilipin 2 (PLIN2), a structural coat protein located on the…”
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Ovarian inflammation mediated by Toll-like receptor 4 increased transcripts of maternal effect genes and decreased embryo development
Published in Biology of reproduction (13-03-2023)“…Obese women are subfertile and have reduced assisted reproduction success, which may be due to reduced oocyte competence. We hypothesize that consumption of a…”
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Luteinizing hormone regulates the phosphorylation and localization of the mitochondrial effector dynamin‐related protein‐1 (DRP1) and steroidogenesis in the bovine corpus luteum
Published in The FASEB journal (01-04-2020)“…The corpus luteum is an endocrine gland that synthesizes and secretes progesterone. Luteinizing hormone (LH) activates protein kinase A (PKA) signaling in…”
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Trafficking of cholesterol from lipid droplets to mitochondria in bovine luteal cells: Acute control of progesterone synthesis
Published in The FASEB journal (01-08-2020)“…The corpus luteum is a transient endocrine gland that synthesizes and secretes the steroid hormone, progesterone, which is vital for establishment and…”
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Obesity-Dependent Increases in Oocyte mRNAs Are Associated With Increases in Proinflammatory Signaling and Gut Microbial Abundance of Lachnospiraceae in Female Mice
Published in Endocrinology (Philadelphia) (01-04-2016)“…RNAs stored in the metaphase II-arrested oocyte play important roles in successful embryonic development. Their abundance is defined by transcriptional…”
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