Search Results - "Wood, JG"
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A review of economic evaluations of 13-valent pneumococcal conjugate vaccine (PCV13) in adults and the elderly
Published in Human vaccines & immunotherapeutics (03-04-2015)“…The 13-valent pneumococcal conjugated vaccine (PCV13) is already recommended for some adult groups and is being considered for wider use in many countries. In…”
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Sirtuin activators mimic caloric restriction and delay ageing in metazoans
Published in Nature (05-08-2004)“…Caloric restriction extends lifespan in numerous species. In the budding yeast Saccharomyces cerevisiae this effect requires Sir2 (ref. 1), a member of the…”
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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
Published in Nature (11-09-2003)“…In diverse organisms, calorie restriction slows the pace of ageing and increases maximum lifespan. In the budding yeast Saccharomyces cerevisiae, calorie…”
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Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae
Published in Nature (London) (08-05-2003)“…Calorie restriction extends lifespan in a broad range of organisms, from yeasts to mammals. Numerous hypotheses have been proposed to explain this phenomenon,…”
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Beyond expectations: Post-implementation data shows rotavirus vaccination is likely cost-saving in Australia
Published in Vaccine (05-01-2017)“…Highlights • The Australian infant rotavirus immunisation program was estimated to be cost-saving. • Larger than predicted reductions in gastroenteritis coded…”
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Small molecules that regulate lifespan: evidence for xenohormesis
Published in Molecular microbiology (01-08-2004)“…Barring genetic manipulation, the diet known as calorie restriction (CR) is currently the only way to slow down ageing in mammals. The fact that CR works on…”
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Retrospective economic evaluation of childhood 7-valent pneumococcal conjugate vaccination in Australia: Uncertain herd impact on pneumonia critical
Published in Vaccine (12-01-2016)“…Highlights • There were substantial health benefits from the childhood PCV7 program in Australia. • Attribution of declines in non-invasive pneumonia mortality…”
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Bowel necrosis caused by water in jejunal feeding
Published in JPEN. Journal of parenteral and enteral nutrition (01-01-2004)“…BACKGROUND: Fifteen reports of bowel necrosis in patients receiving jejunal feeding have been reported. Etiology remains unexplained. METHODS: A patient with a…”
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Economic evaluations of implemented vaccination programmes: key methodological challenges in retrospective analyses
Published in Vaccine (07-02-2014)“…Highlights • Economic evaluation of existing vaccine programmes presents specific challenges. • Post-implementation surveillance data have the capacity to…”
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Manipulation of a Nuclear NAD+ Salvage Pathway Delays Aging without Altering Steady-state NAD+ Levels
Published in The Journal of biological chemistry (24-05-2002)“…Yeast deprived of nutrients exhibit a marked life span extension that requires the activity of the NAD+-dependent histone deacetylase, Sir2p. Here we show that…”
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Changes in seroprevalence to hepatitis A in Victoria, Australia: A comparison of three time points
Published in Vaccine (14-09-2012)“…Highlights ► We examined trends in population hepatitis A seroepidemiology over a 20-year period. ► A significant trend of increasing population hepatitis A…”
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Mast cells mediate the microvascular inflammatory response to systemic hypoxia
Published in Journal of applied physiology (1985) (01-01-2003)“…Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160 Systemic hypoxia produces an inflammatory…”
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Phosphorylation of human tau protein by microtubule-associated kinases: GSK3β and cdk5 are key participants
Published in Journal of neuroscience research (01-11-2000)“…Microtubules (MTs), primarily composed of α and β tubulin polymers, must often work in concert with microtubule‐associated proteins (MAPs) in order to modulate…”
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Unusual Proliferation Arrest and Transcriptional Control Properties of a Newly Discovered E2F Family Member, E2F-6
Published in Proceedings of the National Academy of Sciences - PNAS (04-08-1998)“…E2F transcription factors play an important role in the regulation of cell cycle progression. We report here the cloning and characterization of an additional…”
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Transgenic zebrafish model of neurodegeneration
Published in Journal of neuroscience research (15-12-2002)“…In Alzheimer's disease (AD), the microtubule‐associated protein, tau, is compromised in its normal association with microtubules and forms into paired helical…”
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Leukotriene B 4 promotes reactive oxidant generation and leukocyte adherence during acute hypoxia
Published in Journal of applied physiology (1985) (01-09-2001)“…Acute systemic hypoxia produces rapid leukocyte adherence in the rat mesenteric microcirculation, although the underlying mechanisms are not fully known…”
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In vivo visualization of reactive oxidants and leukocyte-endothelial adherence following hemorrhagic shock
Published in Shock (Augusta, Ga.) (01-11-2002)“…The generation of oxygen radicals during leukocyte-endothelial cell interaction is considered to represent one of the fundamental steps of microvascular injury…”
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Interaction between reactive oxygen species and nitric oxide in the microvascular response to systemic hypoxia
Published in Journal of applied physiology (1985) (01-10-2002)“…Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160 Systemic hypoxia results in oxidative stress…”
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Systemic hypoxia increases leukocyte emigration and vascular permeability in conscious rats
Published in Journal of applied physiology (1985) (01-10-2000)“…Departments of 1 Molecular and Integrative Physiology and 2 Pediatrics, University of Kansas Medical Center, Kansas City, Kansas 66160 We recently observed…”
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Leukocyte-endothelial interactions in environmental hypoxia
Published in Advances in experimental medicine and biology (01-01-2001)“…Hypoxia induced by reducing inspired PO2 (PIO2) to 70 Torr, promotes a rapid microvascular response characterized by increased leukocyte rolling and adherence…”
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