Search Results - "Wood, J F"

Construction, binding properties, metabolism, and tumor targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49 by MILENIC, D. E, YOKOTA, T, FILPULA, D. R, FINKELMAN, M. A. J, DODD, S. W, WOOD, J. F, WHITLOW, M, SNOY, P, SCHLOM, J

“…CC49 is a "second generation" monoclonal antibody to B72.3, which reacts with the pancarcinoma antigen TAG-72. CC49 has been shown to efficiently target human…”
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Quantum paraelectric varactors for radiofrequency measurements at millikelvin temperatures by Apostolidis, P., Villis, B. J., Chittock-Wood, J. F., Powell, J. M., Baumgartner, A., Vesterinen, V., Simbierowicz, S., Hassel, J., Buitelaar, M. R.

“…Radiofrequency reflectometry can provide fast and sensitive electrical read-out of charge and spin qubits in quantum dot devices coupled to resonant circuits…”
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An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability by Whitlow, M, Bell, B A, Feng, S L, Filpula, D, Hardman, K D, Hubert, S L, Rollence, M L, Wood, J F, Schott, M E, Milenic, D E

“…The effects of linker length on binding affinity and degree of aggregation have been examined in the antifluorescein 4-4-20 and anticarcinoma CC49 single-chain…”
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Microautoradiographic analysis of the normal organ distribution of radioiodinated single-chain Fv and other immunoglobulin forms by YOKOTA, T, MILENIC, D. E, WHITLOW, M, WOOD, J. F, HUBERT, S. L, SCHLOM, J

“…In previous studies, we have compared the immunochemical properties, the in vivo pharmacokinetics, and the tumor penetrance of a radioiodinated single-chain Fv…”
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Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding by Pantoliano, Michael W, Whitlow, Marc, Wood, Jay F, Dodd, Steven W, Hardman, Karl D, Rollence, Michele L, Bryan, Philip N

“…Six individual amino acid substitutions at separate positions in the tertiary structure of subtilisin BPN' (EC 3.4.21.14) were found to increase the stability…”
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Differential metabolic patterns of iodinated versus radiometal chelated anticarcinoma single-chain Fv molecules by SCHOTT, M. E, MILENIC, D. E, YOKOTA, T, WHITLOW, M, WOOD, J. F, FORDYCE, W. A, CHENG, R. C, SCHLOM, J

“…Genetically engineered single-chain Fvs (sFv) are defined as recombinant proteins composed of a variable light chain amino acid sequence of an immunoglobulin…”
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Understanding Men's Health and Illness: A Gender-relations Approach to Policy, Research, and Practice by Schofield, Toni, Connell, R. W., Walker, Linley, Wood, Julian F., Butland, Dianne L.

“…Men's health has emerged as an important public concern that may require new kinds of healthcare interventions and increased resources. Considerable…”
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Crystallization of single-chain Fv proteins by Essig, N Z, Wood, J F, Howard, A J, Raag, R, Whitlow, M

“…Single-chain Fv (sFv) proteins consist of the variable heavy chain (VH) and variable light chain (VL) domains of an antibody, covalently joined by an…”
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Glipizide pharmacokinetics: effects of age, diabetes, and multiple dosing by Kradjan, W A, Kobayashi, K A, Bauer, L A, Horn, J R, Opheim, K E, Wood, Jr, F J

“…Aging and disease may contribute to alterations in drug pharmacokinetics. The purpose of this study was to determine the effects of aging, the presence of…”
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Nutritional Evaluation of the Starchy Flour Obtained from Cassava Tubers on Fermentation with a Mixed-Culture Inoculum by Padmaja, G, George, Mathew, Moorthy, S. N, Bainbridge, Zoe, Plumb, Vanessa, Wood, J. F, Powell, C. J

“…Cassava fermentation improves its textural qualities and reduces the level of toxic cyanogenic glucosides. A mixed-culture inoculum comprising Lactobacillus…”
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Bulk power system restoration training techniques by COOPER, M. E, ADIBI, M. M, WAIGHT, J. G, HOFFMAN, R, FINK, L. H, WASLEY, R. G, GONZALES, R. T, STOREY, A. B, WOOD, F. J, KAFKA, R. J, DOBROWOLSKI, E. J, NODEHI, K

“…The authors focus industry attention on various tools and techniques used to develop and implement effective bulk power system restoration training programs…”
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Annual and diurnal cycles in plasma testosterone and thyroxine in the male green sea turtle Chelonia mydas by Licht, P, Wood, J F, Wood, F E

“…Male plasma testosterone (T) and thyroxine (T4) were monitored over several annual cycles in a captive breeding colony of green sea turtles, Chelonia mydas…”
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Multivalent Fvs: characterization of single-chain Fv oligomers and preparation of a bispecific Fv by Whitlow, M, Filpula, D, Rollence, M L, Feng, S L, Wood, J F

“…Single-chain Fv proteins are known to aggregate and form multimeric species. We report here that these molecules represent a new class of molecular assembly,…”
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Protein engineering of subtilisin BPN': enhanced stabilization through the introduction of two cysteines to form a disulfide bond by Pantoliano, Michael W, Ladner, Robert C, Bryan, Philip N, Rollence, Michele L, Wood, Jay F, Poulos, Thomas L

“…Introduction of a disulfide bond by site-directed mutagenesis was found to enhance the stability of subtilisin BPN' (EC 3.4.21.14) under a variety of…”
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Conformational stability, folding, and ligand-binding affinity of single-chain Fv immunoglobulin fragments expressed in Escherichia coli by Pantoliano, Michael W, Bird, Robert E, Johnson, Syd, Asel, Eric D, Dodd, Steven W, Wood, Jay F, Hardman, Karl D

“…A fluorescein-binding single-chain Fv (scFv) was chosen as a model for the study of the physicochemical parameters associated with synthetic IgG fragments…”
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Prof. George W. Todd by WOOD, J. F

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Incorporation of grass silage, whole cereal grains, cassava and cottonseed meal into diets of rabbits kept in a simulated tropical environment by Payne, M, Owen, E, Capper, B S, Wood, J F, Radwan, M A

“…The growth and feed conversion of rabbits fed either grass silage or whole grains and supplementary pelleted concentrate of cassava/cottonseed diets were…”
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The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: subtilisin as a test case by Pantoliano, Michael W, Whitlow, Marc, Wood, Jay F, Rollence, Michele L, Finzel, Barry C, Gilliland, Gary L, Poulos, Thomas L, Bryan, Philip N

“…A weak Ca2+ binding site in the bacterial serine protease subtilisin BPN' (EC 3.4.21.14) was chosen as a model to explore the feasibility of stabilizing a…”
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The Occasional Obstetrician by Wood, J. F.

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Some Observations on Anorexia Nervosa by Kidd, Cecil B., Wood, J. F.

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