Search Results - "Wood, G W"

Quercetin-induced apoptosis acts through mitochondrial- and caspase-3-dependent pathways in human breast cancer MDA-MB-231 cells by Chien, Su-Yu, Wu, Yao-Chung, Chung, Jing-Gung, Yang, Jai-Sing, Lu, Hsu-Feng, Tsou, Mei-Fen, Wood, W G, Kuo, Shou-Jen, Chen, Dar-Ren

“…There has been considerable evidence recently demonstrating the anti-tumour effects of flavonols. Quercetin, an ubiquitous bioactive flavonol, inhibits cells…”
Get more information

Capsaicin mediates apoptosis in human nasopharyngeal carcinoma NPC-TW 039 cells through mitochondrial depolarization and endoplasmic reticulum stress by Ip, S-W, Lan, S-H, Lu, H-F, Huang, A-C, Yang, J-S, Lin, J-P, Huang, H-Y, Lien, J-C, Ho, C-C, Chiu, C-F, Wood, Wg, Chung, J-G

“…Capsaicin, a pungent compound found in hot chili peppers, has been reported to have antitumor activities in many human cancer cell lines, but the induction of…”
Get more information

Spatial learning and memory impairment and increased locomotion in a transgenic amyloid precursor protein mouse model of Alzheimer's disease by Walker, J.M., Fowler, S.W., Miller, D.K., Sun, A.Y., Weisman, G.A., Wood, W.G., Sun, G.Y., Simonyi, A., Schachtman, T.R.

“…► Both age groups of Tg mice showed impaired spatial learning acquisition and retention. ► Such impairment in spatial learning occurred with errors and…”
Get full text

P2Y₂ Nucleotide Receptor-Mediated Responses in Brain Cells by Peterson, Troy S, Camden, Jean M, Wang, Yanfang, Seye, Cheikh I, Wood, W. G, Sun, Grace Y, Erb, Laurie, Petris, Michael J, Weisman, Gary A

“…Acute inflammation is important for tissue repair; however, chronic inflammation contributes to neurodegeneration in Alzheimer's disease (AD) and occurs when…”
Get full text

Amyloid β-protein stimulates trafficking of cholesterol and caveolin-1 from the plasma membrane to the Golgi complex in mouse primary astrocytes by Igbavboa, U, Sun, G.Y, Weisman, G.A, He, Yan, Wood, W.G

“…Abstract The Golgi complex plays a key role in cholesterol trafficking in cells. Our earlier study demonstrated amyloid β-protein (Aβ) alters cholesterol…”
Get full text

EAAT2 as a therapeutic research target in Alzheimer's disease: A systematic review by Wood, Oliver W. G., Yeung, Jason H. Y., Faull, Richard L. M., Kwakowsky, Andrea

“…Glutamate is the main excitatory neurotransmitter in the human central nervous system, responsible for a wide variety of normal physiological processes…”
Get full text

EAAT2 Expression in the Hippocampus, Subiculum, Entorhinal Cortex and Superior Temporal Gyrus in Alzheimer’s Disease by Yeung, Jason H. Y., Palpagama, Thulani H., Wood, Oliver W. G., Turner, Clinton, Waldvogel, Henry J., Faull, Richard L. M., Kwakowsky, Andrea

“…Alzheimer’s disease (AD) is a neuropathological disorder characterized by the presence and accumulation of amyloid-beta plaques and neurofibrillary tangles…”
Get full text

Nonoperative Treatment of Ipsilateral Fractures of the Scapula and Clavicle by Edwards, Scott G, Whittle, A Paige, Wood, George W

“…BackgroundInternal fixation of one or both bones is the recommended treatment for floating shoulder injuries (ipsilateral fractures of the scapula and…”
Get full text

Statins: drugs for Alzheimer's disease? by Eckert, G P, Wood, W G, Müller, W E

“…Evidences from cell culture experiments and animal studies suggest a strong link between cholesterol and Alzheimer's disease (AD). This relationship is…”
Get full text

High-dose chemotherapy and adoptive immunotherapy in the treatment of recurrent pediatric brain tumors by Peres, E, Wood, G W, Poulik, J, Baynes, R, Sood, S, Abidi, M H, Klein, J, Bhambhani, K, Dansey, R, Abella, E

“…Pediatric patients with recurrent brain tumors have a poor prognosis and limited therapeutic options. We investigated the use of high-dose chemotherapy with…”
Get more information

Healing of broken human chromosomes by the addition of telomeric repeats by FLINT, J, CRADDOCK, C. F, VILLEGAS, A, BENTLEY, D. P, WILLIAMS, H. J, GALANELLO, R, CAO, A, WOOD, W. G, AYYUB, H, HIGGS, D. R

“…We have characterized and compared a series of naturally occurring chromosomal truncations involving the terminal region of the short arm of human chromosome…”
Get full text

A major positive regulatory region located far upstream of the human α-globin gene locus by HIGGS, D. R, WOOD, W. G, JARMAN, A. P, SHARPE, J, LIDA, J, PRETORIUS, I.-M, AYYUB, H

“…We have identified a remote, tissue-specific, positive regulatory element that is of major importance in determining the level of human alpha-globin gene…”
Get full text

Effects of aging and β-amyloid on the properties of brain synaptic and mitochondrial membranes by ECKERT, G. P, WOOD, W. G, MÜLLER, W. E

“…The effects of aging and of different amyloid beta-peptides (A beta) on the properties of purified synaptosomal plasma and mitochondrial membranes were studied…”
Get full text

Lipid Binding to Amyloid β‐Peptide Aggregates: Preferential Binding of Cholesterol as Compared with Phosphatidylcholine and Fatty Acids by Avdulov, Nicolai A., Chochina, Svetlana V., Igbavboa, Urule, Warden, Christopher S., Vassiliev, Alexei V., Wood, W. Gibson

“…: Amyloid β‐peptide (Aβ) aggregates are one of the key neuropathological characteristics of Alzheimer's disease. Aβ belongs to a group of proteins that…”
Get full text

Increasing age alters transbilayer fluidity and cholesterol asymmetry in synaptic plasma membranes of mice by Igbavboa, U, Avdulov, N A, Schroeder, F, Wood, W G

“…Previous studies examining age differences in membrane fluidity and cholesterol content have reported on the average or total change in membrane structure,…”
Get more information

Influence of oestrogen and progesterone on macrophage distribution in the mouse uterus by De, M, Wood, G W

“…Macrophages are constituents of all normal connective tissue including the murine uterus. Macrophages have been identified previously in endometrium and…”
Get more information

effect of bupivacaine·HCl on the physical properties of neuronal membranes by Koo, K. I, Bae, J. H, Lee, C. H, Yoon, C. D, Pyun, J. H, Shin, S. H, Jeon, Y. C, Bae, M. K, Jang, H. O, Wood, W. G, Yun, I

“…Fluorescent probe techniques were used to evaluate the effect of bupivacaine·HCl on the physical properties (transbilayer asymmetric lateral and rotational…”
Get full text

Expression of interleukin 1, interleukin 6 and tumour necrosis factor α in mouse uterus during the peri-implantation period of pregnancy by De, M, Sanford, T R, Wood, G W

“…Interleukin 1 (IL-1), IL-6 and tumour necrosis factor alpha (TNF-α) are expressed in the mouse uterus on days 1–3 of pregnancy. Cytokine production is…”
Get full text

Lipid membranes and beta-amyloid: a harmful connection by Eckert, G P, Wood, W G, Müller, W E

“…Gradual changes in steady-state levels of beta amyloid peptides (Abeta) in the brain are considered as initial step in the amyloid cascade hypothesis of…”
Get more information

Murine synaptosomal lipid raft protein and lipid composition are altered by expression of human apoE 3 and 4 and by increasing age by Igbavboa, U., Eckert, G.P., Malo, T.M., Studniski, A.E., Johnson, L.N.A., Yamamoto, N., Kobayashi, M., Fujita, S.C., Appel, T.R., Müller, W.E., Wood, W.G., Yanagisawa, K.

“…Apolipoprotein E (apoE) 4 and aging are risk factors for Alzheimer's disease (AD). Mice expressing human apoE4 and aged wild-type mice show a similarity in the…”
Get full text