Search Results - "Wood, Elizabeth G"

Direct type I IFN but not MDA5/TLR3 activation of dendritic cells is required for maturation and metabolic shift to glycolysis after poly IC stimulation by Pantel, Austin, Teixeira, Angela, Haddad, Elias, Wood, Elizabeth G, Steinman, Ralph M, Longhi, M Paula

“…Type I interferons (IFNs) play an important role in direct antiviral defense as well as linking the innate and adaptive immune responses. On dendritic cells…”
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Obesity and diabetes are major risk factors for epicardial adipose tissue inflammation by Vyas, Vishal, Blythe, Hazel, Wood, Elizabeth G, Sandhar, Balraj, Sarker, Shah-Jalal, Balmforth, Damian, Ambekar, Shirish G, Yap, John, Edmondson, Stephen J, Di Salvo, Carmelo, Wong, Kit, Roberts, Neil, Uppal, Rakesh, Adams, Ben, Shipolini, Alex, Oo, Aung Y, Lawrence, David, Kolvekar, Shyam, Lall, Kulvinder S, Finlay, Malcolm C, Longhi, M Paula

“…BACKGROUNDEpicardial adipose tissue (EAT) directly overlies the myocardium, with changes in its morphology and volume associated with myriad cardiovascular and…”
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Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1 by Yuzugulen, Jale, Douthwaite, Julie A., Wood, Elizabeth G., Villar, Inmaculada C., Patel, Nimesh S. A., Jegard, James, Gaertner, Hubert, Rossitto-Borlat, Irène, Rose, Keith, Hartley, Oliver, Cutillas, Pedro R., Ahluwalia, Amrita, Corder, Roger

“…Endothelin-1 (ET-1) is involved in the pathogenesis of cardiac and renal diseases, and in the progression of tumour growth in cancer, but current diagnosis and…”
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Regulation of Vascular Endothelial Function by Procyanidin-Rich Foods and Beverages by Caton, Paul W, Pothecary, Mark R, Lees, Delphine M, Khan, Noorafza Q, Wood, Elizabeth G, Shoji, Toshihiko, Kanda, Tomomasa, Rull, Gurvinder, Corder, Roger

“…Flavonoid-rich diets are associated with a lower mortality from cardiovascular disease. This has been linked to improvements in endothelial function. However,…”
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Fructose induces gluconeogenesis and lipogenesis through a SIRT1-dependent mechanism by Caton, Paul W, Nayuni, Nanda K, Khan, Noorafza Q, Wood, Elizabeth G, Corder, Roger

“…Consumption of a fructose-rich diet leads to insulin resistance and dyslipidemia in part due to elevated gluconeogenesis and lipogenesis. SIRT1, an…”
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Plasma pro-endothelin-1 peptide concentrations rise in chronic kidney disease and following selective endothelin A receptor antagonism by Dhaun, Neeraj, Yuzugulen, Jale, Kimmitt, Robert A, Wood, Elizabeth G, Chariyavilaskul, Pajaree, MacIntyre, Iain M, Goddard, Jane, Webb, David J, Corder, Roger

“…Endothelin 1 (ET-1) contributes to chronic kidney disease (CKD) development and progression, and endothelin receptor antagonists are being investigated as a…”
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Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets by Macdougall, Claire E., Wood, Elizabeth G., Loschko, Jakob, Scagliotti, Valeria, Cassidy, Féaron C., Robinson, Mark E., Feldhahn, Niklas, Castellano, Leandro, Voisin, Mathieu-Benoit, Marelli-Berg, Federica, Gaston-Massuet, Carles, Charalambous, Marika, Longhi, M. Paula

“…Visceral adipose tissue (VAT) has multiple roles in orchestrating whole-body energy homeostasis. In addition, VAT is now considered an immune site harboring an…”
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Constitutive Activation of β-Catenin in Conventional Dendritic Cells Increases the Insulin Reserve to Ameliorate the Development of Type 2 Diabetes in Mice by Macdougall, Claire E, Wood, Elizabeth G, Solomou, Antonia, Scagliotti, Valeria, Taketo, Makoto Mark, Gaston-Massuet, Carles, Marelli-Berg, Federica M, Charalambous, Marika, Longhi, M Paula

“…β-Cell failure is central to the development of type 2 diabetes mellitus (T2DM). Dysregulation of metabolic and inflammatory processes during obesity…”
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HIF1α activation in dendritic cells under sterile conditions promotes an anti-inflammatory phenotype through accumulation of intracellular lipids by Wood, Elizabeth G., Macdougall, Claire E., Blythe, Hazel, Clément, Marc, Colas, Romain A., Dalli, Jesmond, Marelli-Berg, Federica, Longhi, M. Paula

“…Obesity is among the leading causes of elevated cardiovascular disease mortality and morbidity. Adipose tissue dysfunction, insulin resistance and inflammation…”
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The procyanidin-induced pseudo laminar shear stress response: a new concept for the reversal of endothelial dysfunction by Corder, Roger, Warburton, Richard C, Khan, Noorafza Q, Brown, Ruth E, Wood, Elizabeth G, Lees, Delphine M

“…Reduced endothelium-dependent vasodilator responses with increased synthesis of ET-1 (endothelin-1) are characteristics of endothelial dysfunction in heart…”
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Tissue-resident memory T cells in epicardial adipose tissue comprise transcriptionally distinct subsets that are modulated in atrial fibrillation by Vyas, Vishal, Sandhar, Balraj, Keane, Jack M, Wood, Elizabeth G, Blythe, Hazel, Jones, Aled, Shahaj, Eriomina, Fanti, Silvia, Williams, Jack, Metic, Nasrine, Efremova, Mirjana, Ng, Han Leng, Nageswaran, Gayathri, Byrne, Suzanne, Feldhahn, Niklas, Marelli-Berg, Federica, Chain, Benny, Tinker, Andrew, Finlay, Malcolm C, Longhi, M Paula

“…Atrial fibrillation (AF) is the most common sustained arrhythmia and carries an increased risk of stroke and heart failure. Here we investigated how the immune…”
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Delayed administration of pyroglutamate helix B surface peptide (pHBSP), a novel nonerythropoietic analog of erythropoietin, attenuates acute kidney injury by Patel, Nimesh S A, Kerr-Peterson, Hannah L, Brines, Michael, Collino, Massimo, Rogazzo, Mara, Fantozzi, Roberto, Wood, Elizabeth G, Johnson, Florence L, Yaqoob, Muhammad M, Cerami, Anthony, Thiemermann, Christoph

“…In preclinical studies, erythropoietin (EPO) reduces ischemia-reperfusion-associated tissue injury (for example, stroke, myocardial infarction, acute kidney…”
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Cyclooxygenase expression and prostaglandin levels in central nervous system tissues during the course of chronic relapsing experimental autoimmune encephalomyelitis (EAE) by Ayoub, Samir S., Wood, Elizabeth G., Hassan, Sabih-Ul, Bolton, Christopher

“…Objective Multiple sclerosis (MS) and its animal counterpart experimental autoimmune encephalomyelitis (EAE) have a major inflammatory component that drives…”
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N-methyl-D-aspartate (NMDA) receptor involvement in central nervous system prostaglandin production during the relapse phase of chronic relapsing experimental autoimmune encephalomyelitis (CR EAE) by Bolton, Christopher, Wood, Elizabeth G., Ayoub, Samir S.

“…Our previous studies have established that major changes in central nervous system (CNS) prostaglandin (PG) levels occur during the relapse phase of chronic…”
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Cocoa flavanols reduce N‐terminal pro‐B‐type natriuretic peptide in patients with chronic heart failure by De Palma, Rodney, Sotto, Imelda, Wood, Elizabeth G., Khan, Noorafza Q., Butler, Jane, Johnston, Atholl, Rothman, Martin T., Corder, Roger

“…Aims Poor prognosis in chronic heart failure (HF) is linked to endothelial dysfunction for which there is no specific treatment currently available. Previous…”
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Uniform Collaborative Law Act—An Introduction by TINDALL, HARRY L., WOOD, ELIZABETH G.

“…Collaborative law is a voluntary, nonadversarial settlement process that enables the collaborative parties and lawyers to negotiate a peaceable and equitable…”
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Comparative Evaluation of the Response to Peroxynitrite by a Brain Endothelial Cell Line and Control of the Effects by Drug Targeting by Bolton, Christopher, Wood, Elizabeth G, Scott, Gwen S, Flower, Roderick J

“…The potent oxidant peroxynitrite (ONOO⁻) is formed after the combination of nitric oxide with superoxide and has been closely associated with the pathology of…”
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Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: evidence for intracellular endothelin-converting enzyme by Woods, M, Mitchell, J A, Wood, E G, Barker, S, Walcot, N R, Rees, G M, Warner, T D

“…Endothelin-1 (ET-1) is the predominant endothelin isopeptide generated by the vascular wall and therefore appears to be the most important peptide involved in…”
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Delayed Administration of Pyroglutamate Helix B Surface Peptide (pHBSP), a Novel Nonerythropoietic Analog of Erythropoietin, Attenuates Acute Kidney Injury by Patel, Nimesh S. A., Kerr-Peterson, Hannah L., Brines, Michael, Collino, Massimo, Rogazzo, Mara, Fantozzi, Roberto, Wood, Elizabeth G., Johnson, Florence L., Yaqoob, Muhammad M., Cerami, Anthony, Thiemermann, Christoph

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Inhibitory effect of adrenomedullin on basal and tumour necrosis factor alpha-stimulated endothelin-1 synthesis in bovine aortic endothelial cells is independent of cyclic AMP by Barker, Stewart, Lees, Delphine M, Wood, Elizabeth G, Corder, Roger

“…Adrenomedullin (ADM) is a potent vasodilator and reverses the vasoconstrictor action of endothelin-1 (ET-1). These studies aimed to determine the effect of ADM…”
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