Search Results - "Wood, C David"

Enhancer Control of MicroRNA miR-155 Expression in Epstein-Barr Virus-Infected B Cells by Wood, C David, Carvell, Thomas, Gunnell, Andrea, Ojeniyi, Opeoluwa O, Osborne, Cameron, West, Michelle J

“…The oncogenic microRNA (miRNA) miR-155 is the most frequently upregulated miRNA in Epstein-Barr virus (EBV)-positive B cell malignancies and is upregulated in…”
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MYC activation and BCL2L11 silencing by a tumour virus through the large-scale reconfiguration of enhancer-promoter hubs by Wood, C David, Veenstra, Hildegonda, Khasnis, Sarika, Gunnell, Andrea, Webb, Helen M, Shannon-Lowe, Claire, Andrews, Simon, Osborne, Cameron S, West, Michelle J

“…Lymphomagenesis in the presence of deregulated MYC requires suppression of MYC-driven apoptosis, often through downregulation of the pro-apoptotic BCL2L11 gene…”
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Disruption of CTCF-YY1-dependent looping of the human papillomavirus genome activates differentiation-induced viral oncogene transcription by Pentland, Ieisha, Campos-León, Karen, Cotic, Marius, Davies, Kelli-Jo, Wood, C David, Groves, Ian J, Burley, Megan, Coleman, Nicholas, Stockton, Joanne D, Noyvert, Boris, Beggs, Andrew D, West, Michelle J, Roberts, Sally, Parish, Joanna L

“…The complex life cycle of oncogenic human papillomavirus (HPV) initiates in undifferentiated basal epithelial keratinocytes where expression of the E6 and E7…”
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Pumilio directs deadenylation-associated translational repression of the cyclin-dependent kinase 1 activator RGC-32 by Brocard, Michèle, Khasnis, Sarika, Wood, C David, Shannon-Lowe, Claire, West, Michelle J

“…Abstract Response gene to complement-32 (RGC-32) activates cyclin-dependent kinase 1, regulates the cell cycle and is deregulated in many human tumours. We…”
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Modulation of enhancer looping and differential gene targeting by Epstein-Barr virus transcription factors directs cellular reprogramming by McClellan, Michael J, Wood, C David, Ojeniyi, Opeoluwa, Cooper, Tim J, Kanhere, Aditi, Arvey, Aaron, Webb, Helen M, Palermo, Richard D, Harth-Hertle, Marie L, Kempkes, Bettina, Jenner, Richard G, West, Michelle J

“…Epstein-Barr virus (EBV) epigenetically reprogrammes B-lymphocytes to drive immortalization and facilitate viral persistence. Host-cell transcription is…”
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Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity by Ponnusamy, Rajesh, Khatri, Ritika, Correia, Paulo B, Wood, C David, Mancini, Erika J, Farrell, Paul J, West, Michelle J

“…Natural variation separates Epstein-Barr virus (EBV) into type 1 and type 2 strains. Type 2 EBV is less transforming in vitro due to sequence differences in…”
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Granzyme A Produced by γ9δ2 T Cells Activates ER Stress Responses and ATP Production, and Protects Against Intracellular Mycobacterial Replication Independent of Enzymatic Activity by Rasi, Valerio, Wood, David C., Eickhoff, Christopher S., Xia, Mei, Pozzi, Nicola, Edwards, Rachel L., Walch, Michael, Bovenschen, Niels, Hoft, Daniel F.

“…Mycobacterium tuberculosis (Mtb), the pathological agent that causes tuberculosis (TB) is the number one infectious killer worldwide with one fourth of the…”
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Nuclear localization of p38 MAPK in response to DNA damage by Wood, C David, Thornton, Tina M, Sabio, Guadalupe, Davis, Roger A, Rincon, Mercedes

“…p38 MAP kinase (MAPK) is activated in response to environmental stress, cytokines and DNA damage, and mediates death, cell differentiation and cell cycle…”
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Downregulation of Integrin Receptor-Signaling Genes by Epstein-Barr Virus EBNA 3C via Promoter-Proximal and -Distal Binding Elements by MCCLELLAN, Michael J, KHASNIS, Sarika, WOOD, C. David, PALERMO, Richard D, SCHLICK, Sandra N, KANHERE, Aditi S, JENNER, Richard G, WEST, Michelle J

“…OA  Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
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Reversible Oxidative Modifications in Myoglobin and Functional Implications by Mannino, Mark H., Patel, Rishi S., Eccardt, Amanda M., Janowiak, Blythe E., Wood, David C., He, Fahu, Fisher, Jonathan S.

“…Myoglobin (Mb), an oxygen-binding heme protein highly expressed in heart and skeletal muscle, has been shown to undergo oxidative modifications on both an…”
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Upregulation of the cell-cycle regulator RGC-32 in Epstein-Barr virus-immortalized cells by Schlick, Sandra N, Wood, C David, Gunnell, Andrea, Webb, Helen M, Khasnis, Sarika, Schepers, Aloys, West, Michelle J

“…Epstein-Barr virus (EBV) is implicated in the pathogenesis of multiple human tumours of lymphoid and epithelial origin. The virus infects and immortalizes B…”
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Proteomic Analysis of Human Immune Responses to Live-Attenuated Tularemia Vaccine by Chang, Yie-Hwa, Duong, Duc M., Goll, Johannes B., Wood, David C., Jensen, Travis L., Yin, Luming, Gelber, Casey E., Seyfried, Nicholas T., Anderson, Evan, Natrajan, Muktha S., Rouphael, Nadine, Johnson, Robert A., Sanz, Patrick, Mulligan, Mark J., Hoft, Daniel F.

“…Francisella tularensis (F. tularensis) is an intracellular pathogen that causes a potentially debilitating febrile illness known as tularemia. F. tularensis…”
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Regulation of B cell receptor signalling by Epstein-Barr virus nuclear antigens by Khasnis, Sarika, Veenstra, Hildegonda, McClellan, Michael J, Ojeniyi, Opeoluwa, Wood, C David, West, Michelle J

“…The cancer-associated Epstein-Barr virus (EBV) latently infects and immortalises B lymphocytes. EBV latent membrane protein 2A and EBV-encoded microRNAs are…”
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RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth by Gunnell, Andrea, Webb, Helen M, Wood, C David, McClellan, Michael J, Wichaidit, Billy, Kempkes, Bettina, Jenner, Richard G, Osborne, Cameron, Farrell, Paul J, West, Michelle J

“…In B cells infected by the cancer-associated Epstein-Barr virus (EBV), RUNX3 and RUNX1 transcription is manipulated to control cell growth. The EBV-encoded…”
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Dual Phospholipase C/Diacylglycerol Requirement for Protein Kinase D1 Activation in Lymphocytes by Wood, C. David, Marklund, Ulrica, Cantrell, Doreen A.

“…The serine/threonine kinase protein kinase D1 (PKD1) is a protein kinase C (PKC) substrate that mediates antigen receptor signal transduction in lymphocytes…”
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Crystal Structure of Fatty Acid Amide Hydrolase Bound to the Carbamate Inhibitor URB597: Discovery of a Deacylating Water Molecule and Insight into Enzyme Inactivation by Mileni, Mauro, Kamtekar, Satwik, Wood, David C., Benson, Timothy E., Cravatt, Benjamin F., Stevens, Raymond C.

“…The endocannabinoid system regulates a wide range of physiological processes including pain, inflammation, and cognitive/emotional states. URB597 is one of the…”
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Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D by Wood, C. David, Kelly, April P., Matthews, Sharon A., Cantrell, Doreen A.

“…Phosphoinoisitide dependent kinase l (PDK1) is proposed to phosphorylate a key threonine residue within the catalytic domain of the protein kinase C (PKC)…”
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The protein C activator AB002 rapidly interrupts thrombus development in baboons by Tucker, Erik I., Verbout, Norah G., Markway, Brandon D., Wallisch, Michael, Lorentz, Christina U., Hinds, Monica T., Shatzel, Joseph J., Pelc, Leslie A., Wood, David C., McCarty, Owen J.T., Di Cera, Enrico, Gruber, András

“…Although thrombin is a key enzyme in the coagulation cascade and is required for both normal hemostasis and pathologic thrombogenesis, it also participates in…”
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Correction for Wood et al., "Enhancer Control of MicroRNA miR-155 Expression in Epstein-Barr Virus-Infected B Cells" by Wood, C David, Carvell, Thomas, Gunnell, Andrea, Ojeniyi, Opeoluwa O, Osborne, Cameron, West, Michelle J

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Dissecting the impact of bromodomain inhibitors on the Interferon Regulatory Factor 4‐MYC oncogenic axis in multiple myeloma by Agnarelli, Alessandro, Mitchell, Simon, Caalim, Gillian, Wood, C. David, Milton‐Harris, Leanne, Chevassut, Timothy, West, Michelle J., Mancini, Erika J.

“…B‐cell progenitor fate determinant interferon regulatory factor 4 (IRF4) exerts key roles in the pathogenesis and progression of multiple myeloma (MM), a…”
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