Search Results - "Woo, Yanghee"
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Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions
Published in Genome medicine (29-09-2020)“…Solid tumors such as pancreatic ductal adenocarcinoma (PDAC) comprise not just tumor cells but also a microenvironment with which the tumor cells constantly…”
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2
Gastrectomy for stage IV gastric cancer: a comparison of different treatment strategies from the SEER database
Published in Scientific reports (30-03-2021)“…In the West, more than one third of newly diagnosed subjects show metastatic disease in gastric cancer (mGC) with few care options available. Gastrectomy has…”
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3
An Approach to the Primary and Secondary Prevention of Gastric Cancer in the United States
Published in Clinical gastroenterology and hepatology (01-10-2022)“…Gastric cancer (GC) remains a leading cause of mortality among certain racial, ethnic, and immigrant groups in the United States (US). The majority of GCs are…”
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4
A chimeric poxvirus with J2R (thymidine kinase) deletion shows safety and anti-tumor activity in lung cancer models
Published in Cancer gene therapy (01-04-2020)“…Oncolytic viruses have shown excellent safety profiles in preclinical and clinical studies; however, in most cases therapeutic benefits have been modest. We…”
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Impact of Neoadjuvant Therapy on Minimally Invasive Surgical Outcomes in Advanced Gastric Cancer: An International Propensity Score-Matched Study
Published in Annals of surgical oncology (01-03-2021)“…Background No international consensus on the treatment of advanced gastric cancer (AGC) exists. In the absence of well-designed, comparative studies between…”
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6
Trends and outcomes of robotic surgery for gastrointestinal (GI) cancers in the USA: maintaining perioperative and oncologic safety
Published in Surgical endoscopy (01-11-2020)“…Objective Minimally invasive surgery (MIS) continues to gain traction as a feasible approach for the operative management of gastrointestinal (GI)…”
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7
Lymphadenectomy with Optimum of 29 Lymph Nodes Retrieved Associated with Improved Survival in Advanced Gastric Cancer: A 25,000 Patient International Database Study
Published in Journal of the American College of Surgeons (01-04-2017)“…Abstract Background Gastric adenocarcinoma is an aggressive disease with frequent lymph node(LN) metastases for which lymphadenectomy results in a survival…”
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Oncologic outcomes after robot‐assisted versus laparoscopic distal pancreatectomy: Analysis of the National Cancer Database
Published in Journal of surgical oncology (01-09-2018)“…Background How the oncologic outcomes after robotic distal pancreatectomy (RDP) compare to those after laparoscopic distal pancreatectomy (LDP) remains…”
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9
Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting
Published in Nature communications (07-08-2023)“…Chimeric antigen receptor (CAR) T cell therapeutic responses are hampered by limited T cell trafficking, persistence, and durable anti-tumor activity in solid…”
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10
PIPAC for the Treatment of Gynecologic and Gastrointestinal Peritoneal Metastases: Technical and Logistic Considerations of a Phase 1 Trial
Published in Annals of surgical oncology (2022)“…Background Peritoneal metastases (PM) from ovarian, gastric, appendiceal, or colorectal origin can be treated via cytoreductive surgery with or without the…”
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11
Fluorescent imaging for cancer therapy and cancer gene therapy
Published in Molecular therapy. Oncolytics (17-12-2021)“…The translation of laboratory science into effective clinical cancer therapy is gaining momentum more rapidly than any other time in history. Understanding…”
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12
Anti-Tumor Immunogenicity of the Oncolytic Virus CF33-hNIS-antiPDL1 against Ex Vivo Peritoneal Cells from Gastric Cancer Patients
Published in International journal of molecular sciences (01-09-2023)“…We studied the immunotherapeutic potential of CF33-hNIS-antiPDL1 oncolytic virus (OV) against gastric cancer with peritoneal metastasis (GCPM). We collected…”
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13
Hospital factors strongly influence robotic use in general surgery
Published in Surgery (01-11-2019)“…We hypothesized that general surgeons are more likely to use a robotic surgical platform at hospitals where more urologic and gynecologic robotic operations…”
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14
Tumor and Peritoneum-Associated Macrophage Gene Signature as a Novel Molecular Biomarker in Gastric Cancer
Published in International journal of molecular sciences (01-04-2024)“…A spectrum of immune states resulting from tumor resident macrophages and T-lymphocytes in the solid tumor microenvironment correlates with patient outcomes…”
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15
A Summary of the 2020 Gastric Cancer Summit at Stanford University
Published in Gastroenterology (01-10-2020)“…There exists no coherent national strategy for the early detection or prevention of gastric cancer in the United States (US), even among identified high-risk…”
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Oncolytic poxvirus CF33-hNIS-ΔF14.5 favorably modulates tumor immune microenvironment and works synergistically with anti-PD-L1 antibody in a triple-negative breast cancer model
Published in Oncoimmunology (01-01-2020)“…Triple-negative breast cancer is the most aggressive subtype of breast cancer and is difficult to treat. Breast cancer is considered to be poorly immunogenic…”
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17
Disparate and Alarming Impact of Gastrointestinal Cancers in Young Adult Patients
Published in Annals of surgical oncology (01-02-2021)“…Background The rise in the incidence of gastric cancer (GC) and colorectal cancer (CRC) in young adults (YA) remains unexplained. We aim to identify…”
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18
Sericin nanomicelles with enhanced cellular uptake and pH-triggered release of doxorubicin reverse cancer drug resistance
Published in Drug delivery (2018)“…Drug resistance is the major challenge facing cancer chemotherapy and nanoscale delivery systems based on natural materials, such as sericin, are a promising…”
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Novel oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts and exhibits abscopal effect at a single low dose
Published in Journal of translational medicine (26-04-2018)“…Pancreatic ductal adenocarcinoma (PDAC) has been increasing by 0.5% per year in the United States. PDAC portends a dismal prognosis and novel therapies are…”
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Vitamin D as a Primer for Oncolytic Viral Therapy in Colon Cancer Models
Published in International journal of molecular sciences (01-10-2020)“…Oncolytic viroimmunotherapy is an exciting modality that can offer lasting anti-tumor immunity for aggressive malignancies like colon cancer. The impact of…”
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Journal Article