Search Results - "Woo, Michele"

T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP by Yun, Cai-Hong, Mengwasser, Kristen E, Toms, Angela V, Woo, Michele S, Greulich, Heidi, Wong, Kwok-Kin, Meyerson, Matthew, Eck, Michael J

“…Lung cancers caused by activating mutations in the epidermal growth factor receptor (EGFR) are initially responsive to small molecule tyrosine kinase…”
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Ran-Binding Protein 3 Phosphorylation Links the Ras and PI3-Kinase Pathways to Nucleocytoplasmic Transport by Yoon, Sang-Oh, Shin, Sejeong, Liu, Yuzhen, Ballif, Bryan A., Woo, Michele S., Gygi, Steven P., Blenis, John

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Prognostic Value of DNA Damage Response Genomic Alterations in Relapsed/Advanced Urothelial Cancer by Yin, Ming, Grivas, Petros, Wang, Qi‐En, Mortazavi, Amir, Emamekhoo, Hamid, Holder, Sheldon L., Drabick, Joseph J., Woo, Michele Sue‐Ann, Pal, Sumanta, Vasekar, Monali, Folefac, Edmund, Clinton, Steven K., Monk, Paul, Joshi, Monika

“…Background DNA damage response (DDR) genomic alterations may play an important role in clinical outcomes of patients with urothelial cancer (UC). However, data…”
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Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity by Yun, Cai-Hong, Boggon, Titus J., Li, Yiqun, Woo, Michele S., Greulich, Heidi, Meyerson, Matthew, Eck, Michael J.

“…Mutations in the EGFR kinase are a cause of non-small-cell lung cancer. To understand their mechanism of activation and effects on drug binding, we studied the…”
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A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response by Chen, Zhao, Cheng, Katherine, Walton, Zandra, Wang, Yuchuan, Ebi, Hiromichi, Shimamura, Takeshi, Liu, Yan, Tupper, Tanya, Ouyang, Jing, Li, Jie, Gao, Peng, Woo, Michele S., Xu, Chunxiao, Yanagita, Masahiko, Altabef, Abigail, Wang, Shumei, Lee, Charles, Nakada, Yuji, Peña, Christopher G., Sun, Yanping, Franchetti, Yoko, Yao, Catherine, Saur, Amy, Cameron, Michael D., Nishino, Mizuki, Hayes, D. Neil, Wilkerson, Matthew D., Roberts, Patrick J., Lee, Carrie B., Bardeesy, Nabeel, Butaney, Mohit, Chirieac, Lucian R., Costa, Daniel B., Jackman, David, Sharpless, Norman E., Castrillon, Diego H., Demetri, George D., Jänne, Pasi A., Pandolfi, Pier Paolo, Cantley, Lewis C., Kung, Andrew L., Engelman, Jeffrey A., Wong, Kwok-Kin

“…In parallel with an ongoing human clinical trial, genetically engineered mouse models of lung cancer with different genetic alterations are treated with…”
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Alterations of DNA damage response genes correlate with response and overall survival in anti‐PD‐1/PD‐L1‐treated advanced urothelial cancer by Joshi, Monika, Grivas, Petros, Mortazavi, Amir, Monk, Paul, Clinton, Steven K., Sue‐Ann Woo, Michele, Holder, Sheldon L., Drabick, Joseph J., Yin, Ming

“…DNA damage response (DDR) gene alterations in cancer are associated with a higher tumor mutational burden (TMB) and may impact clinical outcomes of urothelial…”
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Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target by Watanabe, Hideo, Francis, Joshua M, Woo, Michele S, Etemad, Banafsheh, Lin, Wenchu, Fries, Daniel F, Peng, Shouyong, Snyder, Eric L, Tata, Purushothama Rao, Izzo, Francesca, Schinzel, Anna C, Cho, Jeonghee, Hammerman, Peter S, Verhaak, Roel G, Hahn, William C, Rajagopal, Jayaraj, Jacks, Tyler, Meyerson, Matthew

“…The NKX2-1 transcription factor, a regulator of normal lung development, is the most significantly amplified gene in human lung adenocarcinoma. To study the…”
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Implementation of an integrative movement program for residents with dementia in a VA nursing home by Akram, Alirameen, Nicosia, Francesca, Lee, Jennifer, Lee, Maria, Martin, Lynn, Martinez, Steven, Ordoñez, Cherry, Woo, Michele, Barnes, Deborah E

“…Preventing Loss of Independence through Exercise (PLIÉ) is an integrative group movement program developed for adults with mild-to-moderate dementia attending…”
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Ribosomal S6 Kinase (RSK) Regulates Phosphorylation of Filamin A on an Important Regulatory Site by Woo, Michele S., Ohta, Yasutaka, Rabinovitz, Isaac, Stossel, Thomas P., Blenis, John

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Ran-Binding Protein 3 Phosphorylation Links the Ras and PI3-Kinase Pathways to Nucleocytoplasmic Transport by Yoon, Sang-Oh, Shin, Sejeong, Liu, Yuzhen, Ballif, Bryan A., Woo, Michele S., Gygi, Steven P., Blenis, John

“…The major participants of the Ras/ERK and PI3-kinase (PI3K) pathways are well characterized. The cellular response to activation of these pathways, however,…”
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Characterizing the cancer genome in lung adenocarcinoma by Meyerson, Matthew, Weir, Barbara A, Woo, Michele S, Getz, Gad, Perner, Sven, Ding, Li, Beroukhim, Rameen, Lin, William M, Province, Michael A, Kraja, Aldi, Johnson, Laura A, Shah, Kinjal, Sato, Mitsuo, Thomas, Roman K, Barletta, Justine A, Borecki, Ingrid B, Broderick, Stephen, Chang, Andrew C, Chiang, Derek Y, Chirieac, Lucian R, Cho, Jeonghee, Fujii, Yoshitaka, Gazdar, Adi F, Giordano, Thomas, Greulich, Heidi, Hanna, Megan, Johnson, Bruce E, Kris, Mark G, Lash, Alex, Lin, Ling, Lindeman, Neal, Mardis, Elaine R, McPherson, John D, Minna, John D, Morgan, Margaret B, Nadel, Mark, Orringer, Mark B, Osborne, John R, Ozenberger, Brad, Ramos, Alex H, Robinson, James, Roth, Jack A, Rusch, Valerie, Sasaki, Hidefumi, Shepherd, Frances, Sougnez, Carrie, Spitz, Margaret R, Tsao, Ming-Sound, Twomey, David, Verhaak, Roel G. W, Weinstock, George M, Wheeler, David A, Winckler, Wendy, Yoshizawa, Akihiko, Yu, Soyoung, Zakowski, Maureen F, Zhang, Qunyuan, Beer, David G, Wistuba, Ignacio I, Watson, Mark A, Garraway, Levi A, Ladanyi, Marc, Travis, William D, Pao, William, Rubin, Mark A, Gabriel, Stacey B, Gibbs, Richard A, Varmus, Harold E, Wilson, Richard K, Lander, Eric S

“…Somatic alterations in cellular DNA underlie almost all human cancers. The prospect of targeted therapies and the development of high-resolution, genome-wide…”
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Allele-dependent variation in the relative cellular potency of distinct EGFR inhibitors by Yuza, Yuki, Glatt, Karen A, Jiang, Jingrui, Greulich, Heidi, Minami, Yuko, Woo, Michele S, Shimamura, Takeshi, Shapiro, Geoffrey, Lee, Jeffrey C, Ji, Hongbin, Feng, Whei, Chen, Tzu-Hsiu, Yanagisawa, Haruhiko, Wong, Kwok-Kin, Meyerson, Matthew

“…Targeted cancer therapies impede cancer cell growth by inhibiting the function of activated oncogene products. Patients with non-small cell lung cancer and…”
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p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity by Woo, M S, Sánchez, I, Dynlacht, B D

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Influence of Cultural Values on Caregiving Stress for Chinese American Dementia/Alzheimer’s Family Caregivers by Woo, Michele

“…Literature review revealed that stress and coping strategies utilized in caring for a family member with Alzheimer’s and other forms of dementia were…”
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Cyclin pathway genomic alterations across 5,356 prostate cancers by Fontes Jardim, Denis Leonardo, Millis, Sherri Z., Woo, Michele Sue-Ann, Ross, Jeffrey S., Ali, Siraj Mahamed, Kurzrock, Razelle

“…Abstract only 179 Background: The cyclin pathway is comprised of possible targetable alterations as well as resistant alterations that affect treatment,…”
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Landscape of cyclin pathway genomic alterations across 7,207 non-prostate genitourinary tumors by Fontes Jardim, Denis Leonardo, Millis, Sherri Z., Woo, Michele Sue-Ann, Ross, Jeffrey S., Ali, Siraj Mahamed, Kurzrock, Razelle

“…Abstract only 549 Background: Cyclin pathway genomic alterations can be a possible therapeutic target as well as a resistance mechanism for therapy. We…”
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SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas by Meyerson, Matthew, Bass, Adam J, Watanabe, Hideo, Mermel, Craig H, Yu, Soyoung, Perner, Sven, Verhaak, Roel G, Kim, So Young, Wardwell, Leslie, Tamayo, Pablo, Gat-Viks, Irit, Ramos, Alex H, Woo, Michele S, Weir, Barbara A, Getz, Gad, Beroukhim, Rameen, O'Kelly, Michael, Dutt, Amit, Rozenblatt-Rosen, Orit, Dziunycz, Piotr, Komisarof, Justin, Chirieac, Lucian R, LaFargue, Christopher J, Scheble, Veit, Wilbertz, Theresia, Ma, Changqing, Rao, Shilpa, Nakagawa, Hiroshi, Stairs, Douglas B, Lin, Lin, Giordano, Thomas J, Wagner, Patrick, Minna, John D, Gazdar, Adi F, Zhu, Chang Qi, Brose, Marcia S, Cecconello, Ivan, Jr, Ulysses Ribeiro, Marie, Suely K, Dahl, Olav, Shivdasani, Ramesh A, Tsao, Ming-Sound, Rubin, Mark A, Wong, Kwok K, Regev, Aviv, Hahn, William C, Beer, David G, Rustgi, Anil K

“…Matthew Meyerson and colleagues report that SOX2 , which encodes a transcription factor necessary for normal esophageal development, is an amplified lineage…”
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Alterations of DNA damage response (DDR) genes correlate with favorable response and overall survival (OS) in anti-PD-1/PD-L1-treated advanced urothelial cancer (UC) by Joshi, Monika, Grivas, Petros, Mortazavi, Amir, Monk, Paul, Clinton, Steven K., Woo, Michele Sue-Ann, Holder, Sheldon L., Drabick, Joseph J., Yin, Ming

“…Abstract only 438 Background: DDR gene alterations may contribute to higher tumor mutational burden (TMB) via genomic instability in addition to APOBEC…”
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Preventing loss of independence through exercise (PLIÉ) for persons with dementia: A randomized, controlled trial: Dementia care research: Behavioral interventions by Barnes, Deborah E, Lee, Jennifer Ann, Chesney, Margaret A, Yaffe, Kristine, Abrams, Gary, Nicosia, Francesca M, Martinez, Steven, Ordonez, Cherry, Woo, Michele, Boscardin, W John, Mehling, Wolf

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Preventing Loss of Independence through Exercise (PLIÉ): Evaluation of implementation at a VA community living center: Other innovative programs and practices by Akram, Alirameen, Martin, Lynn, Lee, Maria, Nicosia, Francesca M, Martinez, Steven, Woo, Michele, Ordonez, Cherry, Lee, Jennifer Ann, Barnes, Deborah E

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