Search Results - "Woo, Laura"
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Cell–cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (09-02-2016)“…Collective cell responses to exogenous cues depend on cell–cell interactions. In principle, these can result in enhanced sensitivity to weak and noisy stimuli…”
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Dynamic secretome of bone marrow-derived stromal cells reveals a cardioprotective biochemical cocktail
Published in Proceedings of the National Academy of Sciences - PNAS (09-07-2019)“…Transplanted stromal cells have demonstrated considerable promise as therapeutic agents in diverse disease settings. Paracrine signaling can be an important…”
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High-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targets
Published in Journal of molecular and cellular cardiology (01-02-2019)“…Over 5 million people in the United States suffer from heart failure, due to the limited ability to regenerate functional cardiac tissue. One potential…”
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Multi-omic analysis reveals VEGFR2, PI3K, and JNK mediate the small molecule induction of human iPSC-derived cardiomyocyte proliferation
Published in iScience (16-08-2024)“…Mammalian hearts lose their regenerative potential shortly after birth. Stimulating the proliferation of preexisting cardiomyocytes is a potential therapeutic…”
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Abstract P457: Systems Analysis To Understand The Impact Of The CDK Module On Cardiomyocyte Proliferation
Published in Circulation research (03-09-2021)“…RationaleHeart failure is caused by the inability of adult mammalian hearts to overcome the loss of cardiomyocytes (CMs). This is due partly to the limited…”
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Aged hind-limb clasping experimental autoimmune encephalomyelitis models aspects of the neurodegenerative process seen in multiple sclerosis
Published in Proceedings of the National Academy of Sciences - PNAS (05-11-2019)“…Experimental autoimmune encephalomyelitis (EAE) is the most common model of multiple sclerosis (MS). This model has been instrumental in understanding the…”
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Abstract 11378: Dynamic Secretion Analysis by Novel Microfluidic Platform mFLISA Reveal Contextual and Precise Paracrine Signatures Preventing Cardiac Injury
Published in Circulation (New York, N.Y.) (11-11-2016)“…It is now increasingly recognized that a variety of stem cells offer therapeutic benefit to injured tissues via paracrine signaling. Paracrine signaling via…”
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Endothelial signaling of matrix‐bound and diffusible VEGF
Published in The FASEB journal (01-04-2012)“…Abstract only Angiogenesis is a complex morphogenesis process coordinating endothelial cell (EC) signaling through matrix/integrin pathways and growth…”
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Abstract 18674: High-Content Phenotypic Screen for Compounds that Induce Proliferation of Human iPSC-Derived Cardiomyocytes
Published in Circulation (New York, N.Y.) (11-11-2016)“…IntroductionOver 5 million people in the United States are affected by heart failure, a consequence of the heart’s limited ability to regenerate functional…”
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Oxidation by Molecular Oxygen. I. Reactions of a Possible Model System for Mixed-Function Oxidases
Published in Journal of the American Chemical Society (01-08-1964)Get full text
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Cell-cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis
Published 19-08-2015“…Collective cell responses to exogenous cues depend on cell-cell interactions. In principle, these can result in enhanced sensitivity to weak and noisy stimuli…”
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