Search Results - "Woo, John K"
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Early detection of nasopharyngeal carcinoma by plasma Epstein‐Barr virus DNA analysis in a surveillance program
Published in Cancer (15-05-2013)“…BACKGROUND: Nasopharyngeal carcinoma (NPC) is prevalent in Southeast Asia. Over the last decade, plasma Epstein‐Barr virus (EBV) DNA has been developed as a…”
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Analysis of Plasma Epstein–Barr Virus DNA to Screen for Nasopharyngeal Cancer
Published in The New England journal of medicine (10-08-2017)“…Circulating Epstein–Barr virus DNA was measured in 20,174 asymptomatic participants in Hong Kong; 34 of 309 with positive results had nasopharyngeal cancer…”
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Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations
Published in Nature communications (18-01-2017)“…Nasopharyngeal carcinoma (NPC) is an aggressive head and neck cancer characterized by Epstein-Barr virus (EBV) infection and dense lymphocyte infiltration. The…”
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Sequencing-based counting and size profiling of plasma Epstein–Barr virus DNA enhance population screening of nasopharyngeal carcinoma
Published in Proceedings of the National Academy of Sciences - PNAS (29-05-2018)“…Circulating tumor-derived DNA testing for cancer screening has recently been demonstrated in a prospective study on identification of nasopharyngeal carcinoma…”
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Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases
Published in Nature communications (22-07-2019)“…Epstein-Barr virus (EBV) is associated with a number of diseases, including malignancies. Currently, it is not known whether patients with different…”
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Primary Nasopharyngeal Carcinoma: Diagnostic Accuracy of MR Imaging versus that of Endoscopy and Endoscopic Biopsy
Published in Radiology (01-02-2011)“…To compare the accuracy of magnetic resonance (MR) imaging with that of the current clinical standard of endoscopy and endoscopic biopsy, to determine whether…”
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Distinguishing early-stage nasopharyngeal carcinoma from benign hyperplasia using intravoxel incoherent motion diffusion-weighted MRI
Published in European radiology (01-10-2019)“…Objectives MRI can detect early-stage nasopharyngeal carcinoma (NPC), but the detection is more challenging in early-stage NPCs because they must be…”
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Fish bone impaction in the supraglottis
Published in Ear, nose, & throat journal (01-10-2014)“…The most common sites of fish bone impaction are the tonsils, tonsillar pillars, tongue base, valleculae, and piriform fossa. Impaction in the supraglottic…”
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Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape
Published in Nature communications (07-07-2021)“…Interplay between EBV infection and acquired genetic alterations during nasopharyngeal carcinoma (NPC) development remains vague. Here we report a…”
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Recommendations for Epstein-Barr virus–based screening for nasopharyngeal cancer in high- and intermediate-risk regions
Published in JNCI : Journal of the National Cancer Institute (11-04-2023)“…Abstract A meeting of experts was held in November 2021 to review and discuss available data on performance of Epstein-Barr virus (EBV)–based approaches to…”
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Early detection of nasopharyngeal carcinoma: performance of a short contrast-free screening magnetic resonance imaging
Published in JNCI : Journal of the National Cancer Institute (08-05-2024)“…Although contrast-enhanced magnetic resonance imaging (MRI) detects early-stage nasopharyngeal carcinoma (NPC) not detected by endoscopic-guided biopsy (EGB),…”
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Frontal inverted papillomas: A 25‐year study
Published in The Laryngoscope (01-07-2020)“…Objectives/Hypothesis This study analyzes the treatment outcomes of frontal inverted papillomas (FIPs) in an attempt to provide guidelines for surgery…”
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Endoscopic Assessment of the Nasopharynx: An Objective Score of Abnormality to Predict the Likelihood of Malignancy
Published in Annals of otology, rhinology & laryngology (01-02-2010)“…Objectives: We developed an objective endoscopic score of abnormality of the nasopharynx to predict the likelihood of malignancy. Methods: A score sheet with…”
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Quantitative Epstein-Barr Virus DNA Analysis and Detection of Gene Promoter Hypermethylation in Nasopharyngeal (NP) Brushing Samples from Patients with NP Carcinoma
Published in Clinical cancer research (01-08-2002)“…Purpose: Nasopharyngeal carcinoma (NPC) is highly prevalent in southern China and characterized by a strong association with EBV. We aimed to detect EBV DNA…”
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Rhinitis Symptom Utility Index (RSUI) in Chinese Subjects: A Multiattribute Patient-Preference Approach
Published in Quality of life research (01-06-2006)“…Background: The Rhinitis Symptom Utility Index (RSUI), originally developed in the United States, consists of a patient-preference weighting scheme and a…”
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Narrow band imaging endoscopy of the nasopharynx is not more useful than white light endoscopy for suspected nasopharyngeal carcinoma
Published in European archives of oto-rhino-laryngology (01-10-2016)“…Endoscopy is often used to screen for nasopharyngeal carcinoma. A normal nasopharynx on white light endoscopy may yet harbor subclinical or occult malignancy…”
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The Impact of Severe Acute Respiratory Syndrome on Otorhinolaryngological Services at The Prince of Wales Hospital in Hong Kong
Published in The Laryngoscope (01-01-2004)“…Objectives/Hypothesis The objective was to describe the impact of severe acute respiratory syndrome (SARS) on the services of the division of…”
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Treatment results of sinonasal inverted papilloma: an 18-year study
Published in American journal of rhinology & allergy (01-03-2009)“…This article reviews our treatment results of sinonasal inverted papilloma (SNIP) over the past 18 years. A retrospective observational study was performed…”
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Identification of a recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma
Published in The Journal of pathology (01-10-2013)“…Nasopharyngeal carcinoma (NPC) is a distinct type of head and neck cancer which is prevalent in southern China, south‐east Asia and northern Africa. The…”
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