Comprehensive review needed to inform guidance on air quality standards

A 2006 analysis provided evidence that long term exposure to PM2.5 is an important risk factor for cause specific cardiovascular mortality. 3 A 2007 study that followed more than 65800 women in 36 US metropolitan areas for six years found that each increase of 10 [mu]g/m3 in PM2.5 was associated wit...

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Bibliographic Details
Published in:	BMJ (Online) Vol. 348; no. feb19 2; p. g1634
Main Authors:	Wonham, Andrew D, Kliner, Merav, Keenan, Alex, Adeyemi, Olukemi, Atkinson, Jennifer, Dardamissis, Evdokia, Stewart, Alex
Format:	Journal Article
Language:	English
Published:	England British Medical Journal Publishing Group 19-02-2014 BMJ Publishing Group LTD
Subjects:	Air Pollutants - adverse effects Air pollution AMBIENT AIR POLLUTION AND ACUTE CORONARY EVENTS Angina, Unstable - chemically induced Environmental Exposure - adverse effects Female Health risk assessment Humans Long term Male Myocardial Infarction - chemically induced Outdoor air quality
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Summary:	A 2006 analysis provided evidence that long term exposure to PM2.5 is an important risk factor for cause specific cardiovascular mortality. 3 A 2007 study that followed more than 65800 women in 36 US metropolitan areas for six years found that each increase of 10 [mu]g/m3 in PM2.5 was associated with an odds ratio of 1.24 (95% CI 1.09 to 1.41) for the onset of a first cardiovascular event. 4 There are still questions regarding the cardiovascular effects of air pollution, and with few long term studies Cesaroni and colleagues' study contributes to the limited evidence base. 1 Studies presently focus on PM10 and PM2.5, with a gap in the evidence on ultrafine particulate matter (PM0.1).Long term exposure to ambient air pollution and incidence of acute coronary events: prospective cohort study and meta-analysis in 11 European cohorts from the ESCAPE Project.
Bibliography:	SourceType-Other Sources-1 content type line 63 ObjectType-Correspondence-1 ObjectType-Commentary-2
ISSN:	0959-8138 1756-1833 1756-1833
DOI:	10.1136/bmj.g1634