Search Results - "Wongpalee, Somsakul Pop"
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1
Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase
Published in Nature communications (25-05-2021)“…The ability to target epigenetic marks like DNA methylation to specific loci is important in both basic research and in crop plant engineering. However,…”
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2
Large-scale remodeling of a repressed exon ribonucleoprotein to an exon definition complex active for splicing
Published in eLife (24-11-2016)“…Polypyrimidine-tract binding protein PTBP1 can repress splicing during the exon definition phase of spliceosome assembly, but the assembly steps leading to an…”
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3
A DNA methylation reader complex that enhances gene transcription
Published in Science (American Association for the Advancement of Science) (07-12-2018)“…DNA methylation generally functions as a repressive transcriptional signal, but it is also known to activate gene expression. In either case, the downstream…”
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4
Erythropoiesis and Gene Expression Analysis in Erythroid Progenitor Cells Derived from Patients with Hemoglobin H/Constant Spring Disease
Published in International journal of molecular sciences (19-10-2024)“…Hemoglobin H/Constant Spring (Hb H/CS) disease represents a form of non-deletional Hb H disease characterized by chronic hemolytic anemia that ranges from…”
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5
Development of molecular diagnostic platform for α0‐thalassemia 44.6 kb (Chiang Rai, ‐‐CR) deletion in individuals with microcytic red blood cells across Thailand
Published in Annals of human genetics (01-05-2023)“…Introduction The α0‐thalassemia 44.6 kb or Chiang Rai (‐‐CR) deletion has been reported in northern Thailand and is capable of causing hemoglobin (Hb) H…”
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6
CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation
Published in Nature communications (02-09-2019)“…Transcription by RNA polymerase V (Pol V) in plants is required for RNA-directed DNA methylation, leading to transcriptional gene silencing. Global chromatin…”
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7
Highly specific and sensitive detection of Burkholderia pseudomallei genomic DNA by CRISPR-Cas12a
Published in PLoS neglected tropical diseases (01-08-2022)“…Detection of Burkholderia pseudomallei , a causative bacterium for melioidosis, remains a challenging undertaking due to long assay time, laboratory…”
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8
Highly specific and sensitive detection of Burkholderia pseudomallei genomic DNA by CRISPR-Cas12a
Published in PLoS neglected tropical diseases (01-08-2022)“…Detection of Burkholderia pseudomallei, a causative bacterium for melioidosis, remains a challenging undertaking due to long assay time, laboratory…”
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9
Probiotic Limosilactobacillus reuteri KUB-AC5 decreases urothelial cell invasion and enhances macrophage killing of uropathogenic Escherichia coli in vitro study
Published in Frontiers in cellular and infection microbiology (18-07-2024)“…Bacterial urinary tract infections (UTI) are among the most common infectious diseases worldwide. The rise of multidrug-resistant (MDR) uropathogenic (UPEC)…”
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10
Genetic modifications of EGLN1 reactivate HbF production in β0-thalassemia/HbE
Published in Heliyon (30-09-2024)“…Reactivation of fetal hemoglobin (HbF, α2γ2) potentially alleviates clinical presentation in β-thalassemia. Prolyl hydroxylase domain enzymes (PHDs) play roles…”
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11
Insecticide Susceptibility Status of Anopheles and Aedes Mosquitoes in Malaria and Dengue Endemic Areas, Thai–Myanmar Border
Published in Insects (Basel, Switzerland) (09-11-2022)“…The occurrence and spread of insecticide resistance has had a negative effect on the efficacy of insecticide–based tools and is distributed worldwide,…”
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12
Stem-loop 4 of U1 snRNA is essential for splicing and interacts with the U2 snRNP-specific SF3A1 protein during spliceosome assembly
Published in Genes & development (15-11-2014)“…The pairing of 5' and 3' splice sites across an intron is a critical step in spliceosome formation and its regulation. Interactions that bring the two splice…”
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13
Development of molecular diagnostic platform for α 0 -thalassemia 44.6 kb (Chiang Rai, -- CR ) deletion in individuals with microcytic red blood cells across Thailand
Published in Annals of human genetics (01-05-2023)“…The α -thalassemia 44.6 kb or Chiang Rai (-- ) deletion has been reported in northern Thailand and is capable of causing hemoglobin (Hb) H disease and a lethal…”
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14
Antennal morphology and sensilla ultrastructure of the malaria vectors, Anopheles maculatus and An. sawadwongporni (Diptera: Culicidae)
Published in Arthropod structure & development (01-09-2023)“…Mosquitoes rely mainly on the olfactory system to track hosts. Sensilla contain olfactory neuron receptors that perceive different kinds of odorants and…”
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15
Genetic modifications of EGLN1 reactivate HbF production in β 0 -thalassemia/HbE
Published in Heliyon (30-09-2024)“…Reactivation of fetal hemoglobin (HbF, α γ ) potentially alleviates clinical presentation in β-thalassemia. Prolyl hydroxylase domain enzymes (PHDs) play roles…”
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16
Insecticide Susceptibility Status of IAnopheles/I and IAedes/I Mosquitoes in Malaria and Dengue Endemic Areas, Thai–Myanmar Border
Published in Insects (Basel, Switzerland) (01-11-2022)“…This study determined the insecticide susceptibility of malaria and dengue vectors in a co-existing hotspot area, the Thai–Myanmar border. The insecticide…”
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17
Benchmarking CRISPR-BP34 for point-of-care melioidosis detection in low-income and middle-income countries: a molecular diagnostics study
Published in The Lancet. Microbe (01-04-2024)“…Melioidosis is a neglected but often fatal tropical disease. The disease has broad clinical manifestations, which makes diagnosis challenging and time…”
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18
Evaluation of anti-inflammatory, analgesic, and antipyretic activities of the ethanol extract from Murdannia loriformis (Hassk.) Rolla Rao et Kammathy
Published in Bioimpacts (01-01-2014)“…Murdannia loriformis (hassk) Rolla Roa et Kammathy, family Commelinaceae, is used by Chinese practitioners as a remedy for cancer in an early stage, and also…”
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19
The pre-mRNA splicing reaction
Published in Methods in molecular biology (Clifton, N.J.) (2014)“…In eukaryotic organisms, nascent transcripts of protein-coding genes contain intronic sequences that are not present in mature mRNAs. Pre-mRNA splicing removes…”
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