Search Results - "Wong, Victor S C"

Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition by Kalinski, Ashley L, Kar, Amar N, Craver, John, Tosolini, Andrew P, Sleigh, James N, Lee, Seung Joon, Hawthorne, Alicia, Brito-Vargas, Paul, Miller-Randolph, Sharmina, Passino, Ryan, Shi, Liang, Wong, Victor S C, Picci, Cristina, Smith, Deanna S, Willis, Dianna E, Havton, Leif A, Schiavo, Giampietro, Giger, Roman J, Langley, Brett, Twiss, Jeffery L

“…Inhibition of histone deacetylase 6 (HDAC6) was shown to support axon growth on the nonpermissive substrates myelin-associated glycoprotein (MAG) and…”
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Ferroptosis in Neurons and Cancer Cells Is Similar But Differentially Regulated by Histone Deacetylase Inhibitors by Zille, Marietta, Kumar, Amit, Kundu, Nandini, Bourassa, Megan W, Wong, Victor S C, Willis, Dianna, Karuppagounder, Saravanan S, Ratan, Rajiv R

“…Ferroptotic death is a mechanism for tumor suppression by pharmacological inhibitors that target the X transporter (cystine/glutamate antiporter) in a host of…”
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HDAC6 inhibition promotes α-tubulin acetylation and ameliorates CMT2A peripheral neuropathy in mice by Picci, Cristina, Wong, Victor S.C., Costa, Christopher J., McKinnon, Marion C., Goldberg, David C., Swift, Michelle, Alam, Nazia M., Prusky, Glen T., Shen, Sida, Kozikowski, Alan P., Willis, Dianna E., Langley, Brett

“…Charcot-Marie-Tooth type 2A (CMT2A) peripheral neuropathy, the most common axonal form of CMT, is caused by dominantly inherited point mutations in the…”
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Lessons from a postdoc gone wrong by Wong, Victor S C

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Semaphorin 3A induces acute changes in membrane excitability in spiral ganglion neurons in vitro by Wong, Victor S. C., Meadows, Marc, Goldberg, David, Willis, Dianna E.

“…The development and survival of spiral ganglion neurons (SGNs) are dependent on multiple trophic factors as well as membrane electrical activity. Semaphorins…”
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An anchor-tether 'hindered' HCN1 inhibitor is antihyperalgesic in a rat spared nerve injury neuropathic pain model by Tibbs, Gareth R, Uprety, Rajendra, Warren, J David, Beyer, Nicole P, Joyce, Rebecca L, Ferrer, Matthew A, Mellado, Wilfredo, Wong, Victor S C, Goldberg, David C, Cohen, Melanie W, Costa, Christopher J, Li, Zhucui, Zhang, Guoan, Dephoure, Noah E, Barman, Dipti N, Sun, Delin, Ingólfsson, Helgi I, Sauve, Anthony A, Willis, Dianna E, Goldstein, Peter A

“…Neuropathic pain impairs quality of life, is widely prevalent, and incurs significant costs. Current pharmacological therapies have poor/no efficacy and…”
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α-Tubulin Acetyltransferase Is a Novel Target Mediating Neurite Growth Inhibitory Effects of Chondroitin Sulfate Proteoglycans and Myelin-Associated Glycoprotein by Wong, Victor S C, Picci, Cristina, Swift, Michelle, Levinson, Max, Willis, Dianna, Langley, Brett

“…Damage to the CNS results in neuronal and axonal degeneration, and subsequent neurological dysfunction. Endogenous repair in the CNS is impeded by inhibitory…”
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R-spondin-1 Is a Novel β-Cell Growth Factor and Insulin Secretagogue by Wong, Victor S.C., Yeung, Andrea, Schultz, William, Brubaker, Patricia L.

“…R-spondin-1 (Rspo1) is an intestinal growth factor known to exert its effects through activation of the canonical Wnt (cWnt) signaling pathway and subsequent…”
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R-spondin1 deficiency enhances β-Cell neogenesis in a murine model of diabetes by Chahal, Jasleen K, Wong, Victor S C, Chaboissier, Marie-Christine, Brubaker, Patricia L

“…The cWnt activator, R-spondin1 (Rspo1), regulates β-cell growth, function, and neogenesis, although its role in conditions such as streptozotocin (STZ)-induced…”
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