Search Results - "Wong, Sybil C.K."
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The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
Published in Nature cell biology (01-02-2012)“…Oxygen levels regulate the stability of the transcription factor HIF-1 through the action of prolyl hydroxylases and the VHL ubiquitin ligase. Sharp and…”
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Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins
Published in Cell reports (Cambridge) (05-07-2017)“…As core components of the microRNA-induced silencing complex (miRISC), Argonaute (AGO) proteins interact with TNRC6 proteins, recruiting other effectors of…”
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Keys to the kingdom
Published in Nature biotechnology (01-03-2015)“…What you need to know about your technology transfer office…”
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MicroRNA-mediated gene silencing: are we close to a unifying model?
Published in Biomolecular concepts (01-02-2012)“…MicroRNAs (miRNAs) comprise a group of small non-coding RNA –21 nucleotides in length. They act as post-transcriptional regulators of gene expression by…”
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The hypoxic tumor microenvironment: driving the tumorigenesis of non-small-cell lung cancer
Published in Future oncology (London, England) (01-12-2014)“…Since the application of molecular biology in cancer biology, lung cancer research has classically focused on molecular drivers of disease. One such pathway,…”
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