Search Results - "Wong, Stuart J"
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De-Escalation After DE-ESCALATE and RTOG 1016: A Head and Neck Cancer InterGroup Framework for Future De-Escalation Studies
Published in Journal of clinical oncology (01-08-2020)“…Human papillomavirus (HPV)-positive oropharyngeal cancer (OPC) is increasing rapidly. The younger age, significantly improved prognosis, and relative morbidity…”
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Phase III Comparison of Prophylactic Cranial Irradiation Versus Observation in Patients With Locally Advanced Non–Small-Cell Lung Cancer: Primary Analysis of Radiation Therapy Oncology Group Study RTOG 0214
Published in Journal of clinical oncology (20-01-2011)“…This study was conducted to determine if prophylactic cranial irradiation (PCI) improves survival in locally advanced non-small-cell lung cancer (LA-NSCLC)…”
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Phase III Trial of Prophylactic Cranial Irradiation Compared With Observation in Patients With Locally Advanced Non–Small-Cell Lung Cancer: Neurocognitive and Quality-of-Life Analysis
Published in Journal of clinical oncology (20-01-2011)“…There are scant data regarding the effects of prophylactic cranial irradiation (PCI) on neurocognitive function (NCF) and quality of life (QOL). Radiation…”
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Validation of NRG oncology/RTOG‐0129 risk groups for HPV‐positive and HPV‐negative oropharyngeal squamous cell cancer: Implications for risk‐based therapeutic intensity trials
Published in Cancer (15-06-2019)“…Background Radiation Therapy Oncology Group (RTOG)‐0129 recursive partitioning analysis was the basis for risk‐based therapeutic intensification trials for…”
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5
Reirradiation for Head and Neck Cancer: The Who and the How
Published in International journal of radiation oncology, biology, physics (01-03-2018)Get full text
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Locally Recurrent, Previously Irradiated Head and Neck Cancer: Concurrent Re-Irradiation and Chemotherapy, or Chemotherapy Alone?
Published in Journal of clinical oncology (10-06-2006)“…Patients with locally recurrent head and neck cancer previously treated with radiation have a poor prognosis. Administration of a second course of radiation to…”
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Erlotinib and bevacizumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck: a phase I/II study
Published in The lancet oncology (01-03-2009)“…Summary Background Epidermal growth factor receptor (EGFR) is a validated target in squamous-cell carcinoma of the head and neck, but in patients with…”
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A Phase II Study of Lapatinib in Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck
Published in Clinical cancer research (15-04-2012)“…This study sought to determine the efficacy and safety profile of lapatinib in patients with recurrent/metastatic squamous cell carcinoma of the head and neck…”
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9
The Not Knowing Is the Hardest Part
Published in International journal of radiation oncology, biology, physics (01-04-2017)Get full text
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Radiation Therapy Oncology Group 0247: A Randomized Phase II Study of Neoadjuvant Capecitabine and Irinotecan or Capecitabine and Oxaliplatin With Concurrent Radiotherapy for Patients With Locally Advanced Rectal Cancer
Published in International journal of radiation oncology, biology, physics (15-03-2012)“…Purpose To evaluate the rate of pathologic complete response (pCR) and the toxicity of two neoadjuvant chemoradiotherapy (chemoRT) regimens for Stage T3-T4…”
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Efficacy Endpoints of Radiation Therapy Group Protocol 0247: A Randomized, Phase 2 Study of Neoadjuvant Radiation Therapy Plus Concurrent Capecitabine and Irinotecan or Capecitabine and Oxaliplatin for Patients With Locally Advanced Rectal Cancer
Published in International journal of radiation oncology, biology, physics (2015)“…Purpose To report secondary efficacy endpoints of Radiation Therapy Oncology Group protocol 0247, primary endpoint analysis of which demonstrated that…”
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Comparison of Physical Examination and Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography 4–6 Months After Radiotherapy to Assess Residual Head-and-Neck Cancer
Published in International journal of radiation oncology, biology, physics (01-12-2011)“…Purpose To retrospectively compare fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) and physical examination 4–6 months after…”
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A phase 2 trial of a topical antiseptic bundle in head and neck cancer surgery: Effects on surgical site infection and the oral microbiome
Published in EBioMedicine (01-07-2022)“…Head and neck cancer (HNC) surgery remains an important component of management but is associated with a high rate of surgical site infection (SSI). We aimed…”
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Clinical Outcomes of Patients Receiving Integrated PET/CT-Guided Radiotherapy for Head and Neck Carcinoma
Published in International journal of radiation oncology, biology, physics (01-03-2008)“…Purpose We previously reported the advantages of18 F-fluorodeoxyglucose–positron emission tomography (PET) fused with CT for radiotherapy planning over CT…”
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15
Good Radiosensitizer Hunting
Published in Journal of clinical oncology (01-05-2023)Get full text
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Retreatment of Recurrent Head and Neck Cancer in a Previously Irradiated Field
Published in Seminars in radiation oncology (01-07-2012)“…During the past 2 decades, concurrent chemotherapy with reirradiation (reRT) has matured from a fear-provoking, rarely performed therapeutic strategy to an…”
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Development and Validation of Nomograms Predictive of Overall and Progression-Free Survival in Patients With Oropharyngeal Cancer
Published in Journal of clinical oncology (20-12-2017)“…Purpose Treatment of oropharyngeal squamous cell carcinoma (OPSCC) is evolving toward risk-based modification of therapeutic intensity, which requires…”
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Cancer trials as opportunities to serve and learn from individuals with human immunodeficiency virus
Published in Cancer (01-03-2023)“…Despite strong recommendations for their inclusion in cancer clinical trials, people living with human immunodeficiency virus continue to be underrepresented…”
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Pharmacokinetic Characterization and Bioavailability Barrier for the Key Active Components of Botanical Drug Antitumor B (ATB) in Mice for Chemoprevention of Oral Cancer
Published in Journal of natural products (Washington, D.C.) (24-09-2021)“…This study aims to characterize the pharmacokinetic (PK) profiles and identify important bioavailability barriers and pharmacological pathways of the key…”
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Profiling of 149 Salivary Duct Carcinomas, Carcinoma Ex Pleomorphic Adenomas, and Adenocarcinomas, Not Otherwise Specified Reveals Actionable Genomic Alterations
Published in Clinical cancer research (15-12-2016)“…We sought to identify genomic alterations (GA) in salivary gland adenocarcinomas, not otherwise specified (NOS), salivary duct carcinomas (SDC), carcinoma ex…”
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