Search Results - "Wong, Si Nga"
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Towards the discovery of unrevealed flufenamic acid cocrystals via structural resemblance for enhanced topical drug delivery
Published in International journal of pharmaceutics (01-01-2025)“…[Display omitted] Cocrystallization has emerged as a promising formulation strategy for modulating transdermal drug absorption by enhancing solubility and…”
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Rational Development of a Carrier-Free Dry Powder Inhalation Formulation for Respiratory Viral Infections via Quality by Design: A Drug-Drug Cocrystal of Favipiravir and Theophylline
Published in Pharmaceutics (27-01-2022)“…Formulating pharmaceutical cocrystals as inhalable dosage forms represents a unique niche in effective management of respiratory infections. Favipiravir, a…”
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Effects of the Glass-Forming Ability and Annealing Conditions on Cocrystallization Behaviors via Rapid Solvent Removal: A Case Study of Voriconazole
Published in Pharmaceutics (14-12-2020)“…The kinetic entrapment of molecules in an amorphous phase is a common obstacle to cocrystal screening using rapid solvent removal, especially for drugs with a…”
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Nanoparticulate Drug Delivery to the Retina
Published in Molecular pharmaceutics (01-02-2021)“…Retinal diseases, such as age-related macular degeneration and diabetic retinopathy, are the leading causes of blindness worldwide. The mainstay of treatment…”
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Synthesis of the first remdesivir cocrystal: design, characterization, and therapeutic potential for pulmonary delivery
Published in International journal of pharmaceutics (10-06-2023)“…[Display omitted] While cocrystal engineering is an emerging formulation strategy to overcome drug delivery challenges, its therapeutic potential in non-oral…”
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Converting nanosuspension into inhalable and redispersible nanoparticles by combined in-situ thermal gelation and spray drying
Published in European journal of pharmaceutics and biopharmaceutics (01-04-2020)“…[Display omitted] While nanoparticulate drugs for deep lung delivery hold promise for particular disease treatments, their size-related physical instability…”
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Extended Release of Highly Water Soluble Isoniazid Attained through Cocrystallization with Curcumin
Published in Crystal growth & design (04-03-2020)“…The aim of this study was to design and evaluate a cocrystal capable of releasing a highly water soluble drug, isoniazid (INH), over a period of longer than…”
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Cocrystallization of Curcumin with Benzenediols and Benzenetriols via Rapid Solvent Removal
Published in Crystal growth & design (05-09-2018)“…Recent advances in crystal engineering by cocrystallization have offered a promising approach for tackling undesirable physicochemical properties of drug…”
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Cocrystal Engineering of Itraconazole with Suberic Acid via Rotary Evaporation and Spray Drying
Published in Crystal growth & design (01-05-2019)“…Cocrystallization represents an emerging approach to tackle the issues associated with pharmaceutical product performance and processing, owing to its…”
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Development of favipiravir dry powders for intranasal delivery: An integrated cocrystal and particle engineering approach via spray freeze drying
Published in International journal of pharmaceutics (25-03-2024)“…[Display omitted] The therapeutic potential of pharmaceutical cocrystals in intranasal applications remains largely unexplored despite progressive advancements…”
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Interplay between Amphiphilic Stabilizers and Cholesterol in the Stabilization of Itraconazole Nanoparticles Prepared by Flash Nanoprecipitation
Published in Molecular pharmaceutics (07-01-2019)“…While flash nanoprecipitation (FNP) has proven to be an extremely rapid and highly efficient nanoparticle fabrication process for hydrophobic drugs, physical…”
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Integrated Continuous Plug-Flow Crystallization and Spray Drying of Pharmaceuticals for Dry Powder Inhalation
Published in Industrial & engineering chemistry research (11-09-2019)“…The manufacture of dry powders for pulmonary drug delivery is complicated by stringent requirements for the aerodynamic size distribution and solid-state…”
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Detection of diverse viruses in alimentary specimens of bats in Macau
Published in Virologica Sinica (01-06-2017)“…Bats carry a variety of viruses, and some of them cause public health problems. Macau, which is famous for its gambling industry, has a complex population…”
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