Search Results - "Wong, S.T.C."

Automated segmentation, classification, and tracking of cancer cell nuclei in time-lapse microscopy by Xiaowei Chen, Xiaobo Zhou, Wong, S.T.C.

“…Quantitative measurement of cell cycle progression in individual cells over time is important in understanding drug treatment effects on cancer cells. Recent…”
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Methods of dendritic spine detection: From Golgi to high-resolution optical imaging by Mancuso, J.J, Chen, Y, Li, X, Xue, Z, Wong, S.T.C

“…Highlights ► Golgi staining and manual spine identification have provided insight into neurodegeneration. ► Advances in microscopy and tissue labeling have…”
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Automatic Segmentation of High-Throughput RNAi Fluorescent Cellular Images by Yan, Pingkun, Zhou, Xiaobo, Shah, Mubarak, Wong, Stephen T. C.

“…High-throughput genome-wide RNA interference (RNAi) screening is emerging as an essential tool to assist biologists in understanding complex cellular…”
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A Novel Cell Segmentation Method and Cell Phase Identification Using Markov Model by Xiaobo Zhou, Fuhai Li, Jun Yan, Wong, S.T.C.

“…Optical microscopy is becoming an important technique in drug discovery and life science research. The approaches used to analyze optical microscopy images are…”
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Segmentation of touching cell nuclei using gradient flow tracking by LI, G, LIU, T, NIE, J, GUO, L, CHEN, J, ZHU, J, XIA, W, MARA, A, HOLLEY, S, WONG, S.T.C

“…Reliable cell nuclei segmentation is an important yet unresolved problem in biological imaging studies. This paper presents a novel computerized method for…”
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Image segmentation by EM-based adaptive pulse coupled neural networks in brain magnetic resonance imaging by Fu, J.C, Chen, C.C, Chai, J.W, Wong, S.T.C, Li, I.C

“…Abstract We propose an automatic hybrid image segmentation model that integrates the statistical expectation maximization (EM) model and the spatial pulse…”
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Image segmentation feature selection and pattern classification for mammographic microcalcifications by Fu, J.C., Lee, S.K., Wong, S.T.C., Yeh, J.Y., Wang, A.H., Wu, H.K.

“…Since microcalcifications in X-ray mammograms are the primary indicator of breast cancer, detection of microcalcifications is central to the development of an…”
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Limitations of Wada memory asymmetry as a predictor of outcomes after temporal lobectomy by Kirsch, H E, Walker, J A, Winstanley, F S, Hendrickson, R, Wong, S T C, Barbaro, N M, Laxer, K D, Garcia, P A

“…The intracarotid amobarbital (Wada) test can be used to evaluate hemispheric memory capacity before anterior temporal lobectomy (ATL). Most patients…”
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Computational Prediction Models for Early Detection of Risk of Cardiovascular Events Using Mass Spectrometry Data by Pham, T.D., Honghui Wang, Xiaobo Zhou, Dominik Beck, Brandl, M., Hoehn, G., Azok, J., Brennan, M.-L., Hazen, S.L., Li, K., Wong, S.T.C.

“…Early prediction of the risk of cardiovascular events in patients with chest pain is critical in order to provide appropriate medical care for those with…”
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Workflow-enabled distributed component-based information architecture for digital medical imaging enterprises by Wong, S.T.C., Tjandra, D., Huili Wang, Weimin Shen

“…Few information systems today offer a flexible means to define and manage the automated part of radiology processes, which provide clinical imaging services…”
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DBMap: a space-conscious data visualization and knowledge discovery framework for biomedical data warehouse by Ming Zhang, Hong Zhang, Tjandra, D., Wong, S.T.C.

“…Advances in digital imaging modalities as well as other diagnosis and therapeutic techniques have generated a massive amount of diverse data for clinical…”
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Identification of a novel biomarker response in a prospective clinical trial of immune checkpoint blockade in high-grade serous ovarian carcinoma by Cun, H., Hinchcliff, E.M., Zhu, Y., Ferri-Borgogno, S., Cheng, R., Burks, J.K., Wong, S.T.C., Jazaeri, A.A., Mok, S.C.

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Development of novel biomarkers for early detection of high-grade serous ovarian cancer in high-risk women using exosomal miRNAs by Cun, H., Sheng, J., Cheng, R., Ferri-Borgogno, S., Kim, J.H., Han, G.H., Celestino, J., Lu, K.H., Wong, S.T.C., Mok, S.C.

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Automated dynamic cellular analysis in high throughput drug screens by Xiaowei Chen, Wong, S.T.C.

“…To understand drug effects on cancer cells better, it is important to analyze cell nuclei dynamics from time-lapse fluorescence microscopy data. Existing…”
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Constraint factor graph cut-based active contour method for automated cellular image segmentation in RNAi screening by CHEN, C, LI, H, ZHOU, X, WONG, S.T.C

“…Image-based, high throughput genome-wide RNA interference (RNAi) experiments are increasingly carried out to facilitate the understanding of gene functions in…”
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VOLES: Vascularity-Oriented LEvel Set algorithm for pulmonary vessel segmentation in image guided intervention therapy by Xiangjun Zhu, Zhong Xue, Xin Gao, Yisheng Zhu, Wong, S.T.C.

“…Delicate surgical planning and accurate guidance plays an important role in successful image guided intervention. In interventional lung cancer diagnosis and…”
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Cross-platform method for identifying candidate network biomarkers for prostate cancer by Jin, G, Zhou, X, Cui, K, Zhang, X-S, Chen, L, Wong, S T C

“…Discovering biomarkers using mass spectrometry (MS) and microarray expression profiles is a promising strategy in molecular diagnosis. Here, the authors…”
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confident scale-space shape representation framework for cell migration detection by ZHANG, K, XIONG, H, ZHOU, X, YANG, L, WANG, Y.-L, WONG, S.T.C

“…Automated segmentation of time-lapse images is a method to facilitate the understanding of the intricate biological progression, e.g. cancer cell migration. To…”
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A novel surface-based geometric approach for 3D dendritic spine detection from multi-photon excitation microscopy images by Qing Li, Xiaobo Zhou, Zhigang Deng, Baron, M., Teylan, M.A., Yong Kim, Wong, S.T.C.

“…Determining the relationship between the dendritic spine morphology and its functional properties is a fundamental while challenging problem in neurobiology…”
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Integrating multi-scale blob/curvilinear detector techniques and multi-level sets for automated segmentation of stem cell images by Huiming Peng, Xiaobo Zhou, Fuhai Li, Xiaofeng Xia, Wong, S.T.C.

“…Studies of differentiation abilities of stem cells have been attracting a lot of attention over the last years. Microscopy can be used to record details of the…”
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