Search Results - "Wong, Meng Cheong"

Inflammatory Markers and Their Association with Post Stroke Cognitive Decline by Narasimhalu, Kaavya, Lee, Jasinda, Leong, Yi-Lin, Ma, Lu, De Silva, Deidre A., Wong, Meng-Cheong, Chang, Hui-Meng, Chen, Christopher

“…Background Population-based studies have demonstrated the association of inflammation and cognitive impairment. However, few studies to date have examined this…”
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Intracranial Large Artery Disease is Independently Associated with Poor Functional Outcome in a Cohort of Ethnic South Asian Ischemic Stroke Patients by De Silva, Deidre, Wee, Chee-Keong, Woon, Fung-Peng, Chang, Hui-Meng, Wong, Meng-Cheong

“…Background: Intracranial large artery disease (ICLAD) in ischemic stroke patients is associated with an increased risk for recurrent stroke; however, it is not…”
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Retinal microvasculature in acute lacunar stroke: a cross-sectional study by Lindley, Richard I, FRACP, Wang, Jie Jin, PhD, Wong, Meng-Cheong, FRCP, Mitchell, Paul, PhD, Liew, Gerald, PhD, Hand, Peter, MD, Wardlaw, Joanna, MD, De Silva, Deidre A, MRCP, Baker, Michelle, MBBS, Rochtchina, Elena, MAppStat, Chen, Christopher, MRCP, Hankey, Graeme J, FRCP, Chang, Hui-Meng, MRCP, Fung, Victor SC, FRACP, Gomes, Lavier, FRANZCR, Wong, Tien Y, FRANZCO

“…Summary Background Lacunar stroke accounts for a quarter of cases of acute ischaemic stroke; however, its underlying pathophysiology remains unclear. Our aim…”
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PINK1 mutations in sporadic early-onset Parkinson's disease by Tan, Eng-King, Yew, Kenneth, Chua, Eva, Puvan, K., Shen, Hui, Lee, Esther, Puong, Kim-Yoong, Zhao, Yi, Pavanni, Ratnagopal, Wong, Meng-Cheong, Jamora, Dominic, de Silva, Deidre, Moe, Kyaw-Thu, Woon, Fung-Peng, Yuen, Yih, Tan, Louis

“…Pathogenic PINK1 mutations have been described in PARK6‐linked Parkinson's disease (PD) patients of Asian origin. However, data on the frequency of PINK1…”
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Elevated Platelet-Derived Growth Factor AB/BB is Associated with a Lower Risk of Recurrent Vascular Events in Stroke Patients by Narasimhalu, Kaavya, Ma, Lu, De Silva, Deidre Anne, Wong, Meng-Cheong, Chang, Hui-Meng, Chen, Christopher

“…Background Platelet-derived growth factor (PDGF)-AB and BB have been shown to possess angiogenic properties in vivo, and decreased levels have been linked to…”
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A comprehensive association analysis of homocysteine metabolic pathway genes in Singaporean Chinese with ischemic stroke by Low, Hui-Qi, Chen, Christopher P L H, Kasiman, Katherine, Thalamuthu, Anbupalam, Ng, Seok-Shin, Foo, Jia-Nee, Chang, Hui-Meng, Wong, Meng-Cheong, Tai, E-Shyong, Liu, Jianjun

“…The effect of genetic factors, apart from 5,10-methylenetetrahydrofolate reductase (MTHFR) polymorphisms, on elevated plasma homocysteine levels and increasing…”
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Analysis of 14 LRRK2 mutations in Parkinson's plus syndromes and late-onset Parkinson's disease by Tan, E.K., Skipper, Lisa, Chua, Eva, Wong, Meng-Cheong, Pavanni, Ratnagopal, Bonnard, Carine, Kolatkar, Prasanna, Liu, Jian-Jun

“…The pleomorphic pathology of postmortem LRRK2‐positive patients and the frequent association with late‐onset Parkinson's disease (LOPD) symptoms suggest that…”
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Differing Associations of White Matter Lesions and Lacunar Infarction with Retinal Microvascular Signs by Liew, Gerald, Baker, Michelle L., Wong, Tien Y., Hand, Peter J., Wang, Jie Jin, Mitchell, Paul, De Silva, Deidre A., Wong, Meng-Cheong, Rochtchina, Elena, Lindley, Richard I., Wardlaw, Joanna M., Hankey, Graeme J.

“…Background White matter lesions (WML) and lacunar infarcts (LI) are believed to have microvascular etiologies but the exact microvascular changes occurring in…”
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Comprehensive evaluation of common genetic variation within LRRK2 reveals evidence for association with sporadic Parkinson's disease by Skipper, Lisa, Li, Yi, Bonnard, Carine, Pavanni, Ratnagopal, Yih, Yuen, Chua, Eva, Sung, Wing-Kin, Tan, Louis, Wong, Meng-Cheong, Tan, Eng-King, Liu, Jianjun

“…Parkinson's disease (PD) is a complex neurodegenerative disorder whose aetiologies are largely unknown. To date, mutations in six genes have been found causal…”
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Genetic analysis of SCA 2 and 3 repeat expansions in essential tremor and atypical Parkinsonism by Tan, Eng-King, Tong, Justina, Pavanni, Ratnagopal, Wong, Meng-Cheong, Zhao, Yi

“…Anecdotal reports suggest that patients with spinocerebellar ataxia (SCA 2) patients can present with postural tremor with ataxia. We determined the prevalence…”
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Case-control study of UCHL1 S18Y variant in Parkinson's disease by Tan, Eng-King, Puong, Kim-Yoong, Fook-Chong, Stephanie, Chua, Eva, Shen, Hui, Yuen, Yih, Pavanni, Ratnagopal, Wong, Meng-Cheong, Puvan, Kathiravelu, Zhao, Yi

“…A recent meta‐analysis observed a greater significant inverse association of the ubiquitin carboxy‐terminal hydrolase L1 (UCHL1) S18Y variant with Parkinson's…”
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Analysis of LRRK2 Gly2385Arg genetic variant in non-Chinese Asians by Tan, Eng-King, Zhao, Yi, Tan, Louis, Lim, Hui-Qin, Lee, Jasinda, Yuen, Yih, Pavanni, Ratnagopal, Wong, Meng-Cheong, Fook-Chong, Stephanie, Liu, Jian-Jun

“…A common LRRK2 missense variant, Gly2385Arg, has been found to be a genetic risk factor for Parkinson's disease (PD) in ethnic Chinese and Japanese. However,…”
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High Plasma Cyst(e)ine Level May Indicate Poor Clinical Outcome in Patients With Acute Stroke: Possible Involvement of Hydrogen Sulfide by Wong, Peter T. H, Qu, Kun, Chimon, Ghislain N, Seah, Alvin B. H, Chang, Hui Meng, Wong, Meng Cheong, Ng, Yee Kong, Rumpel, Helmut, Halliwell, Barry, Chen, Christopher P. L. H

“…ABSTRACTCysteine is known to cause neuronal cell death and has been reported to be elevated in brain ischemia, but it has not been studied in clinical stroke…”
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Microvascular Structure and Network in the Retina of Patients With Ischemic Stroke by Ong, Yi-Ting, De Silva, Deidre A, Cheung, Carol Y, Chang, Hui-Meng, Chen, Christopher P, Wong, Meng Cheong, Wong, Tien Yin, Ikram, Mohammad Kamran

“…BACKGROUND AND PURPOSE—Microvascular disease has been implicated in the pathogenesis of stroke. The retina provides a window to assess microcirculation…”
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Acute ataxia, Graves' disease, and stiff person syndrome by Chia, Su-Ynn, Chua, Richard, Lo, Yew-Long, Wong, Meng-Cheong, Chan, Ling-Ling, Tan, Eng-King

“…Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's…”
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Comparison of Small Volume Infarcts of Lacunar and Non-Lacunar Etiologies by De Silva, Deidre A., Omar, Eunizar, Manzano, Jennifer J. F., Christensen, Soren, Allen, John C., Bath, Phillip M. W., Chang, Hui-Meng, Wong, Meng-Cheong, Chen, Christopher P. L. H.

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Deep vein thrombosis following ischemic stroke among Asians by De Silva, Deidre Anne, Pey, Huey Bee, Wong, Meng Cheong, Chang, Hui Meng, Chen, Christopher P L H

“…Deep vein thrombosis (DVT) is perceived as uncommon among Asian stroke patients. However, there is a paucity of published data, and thus, we studied the…”
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Metabolic Syndrome Is Associated with Intracranial Large Artery Disease among Ethnic Chinese Patients with Stroke by De Silva, Deidre Anne, MBBS, MRCP, Woon, Fung-Peng, MSc, Lee, Moi-Pin, RVT, Chen, Christopher Li-Hsian, MRCP, FAMS, Chang, Hui-Meng, MBBS, MRCP, Wong, Meng-Cheong, MBBS, MRCP

“…Background The association of metabolic syndrome (MetS) and intracranial large artery disease (ICLAD) has been described, but only in cohorts of ethnic Korean…”
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The Prognostic Effects of Poststroke Cognitive Impairment No Dementia and Domain-Specific Cognitive Impairments in Nondisabled Ischemic Stroke Patients by NARASIMHALU, Kaavya, ANG, Sandy, DE SILVA, Deidre Anne, WONG, Meng-Cheong, CHANG, Hui-Meng, CHIA, Kee-Seng, AUCHUS, Alexander P, CHEN, Christopher P

“…There is some evidence that poststroke dementia, cognitive impairment no dementia (CIND), and mild cognitive impairment predict for poor outcomes such as…”
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Lower incidence of vascular events following small artery ischemic stroke by De Silva, Deidre Anne, Manzano, Jennifer Justice Frogozo, Toh, April, Woon, Fung-Peng, Liu, Erica Yang, Omar, Eunizar, Wong, Wan-Xin, Wong, Tien-Yin, Chen, Christopher P. L. H., Chang, Hui-Meng, Wong, Meng-Cheong

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