Search Results - "Wong, Marcus"

Critical considerations in the formulation development of parenteral biologic drugs by Muralidhara, Bilikallahalli K., Wong, Marcus

“…•Biologic drugs, in general, provide exceptional target specificity and less off-target effects compared to small molecule therapies.•Development and…”
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Emergence of Clinical Salmonella enterica Serovar Typhimurium Isolates with Concurrent Resistance to Ciprofloxacin, Ceftriaxone, and Azithromycin by HO YIN WONG, Marcus, MEIYING YAN, WAI CHI CHAN, Edward, KAN BIAO, SHENG CHEN

“…Salmonella infection is an important public health issue for which the needs of antimicrobial treatment are increasing. A total of 546 human clinical S…”
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Azimuthal decomposition of the radiated noise from supersonic shock-containing jets by Wong, Marcus H., Kirby, Rhiannon, Jordan, Peter, Edgington-Mitchell, Daniel

“…Acoustic measurements of unheated supersonic underexpanded jets with ideally expanded Mach numbers of 1.14, 1.38, and 1.50 are presented. Of the three…”
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The inflammasome pathway is activated by dengue virus non-structural protein 1 and is protective during dengue virus infection by Wong, Marcus P, Juan, Evan Y W, Pahmeier, Felix, Chelluri, Sai S, Wang, Phoebe, Castillo-Rojas, Bryan, Blanc, Sophie F, Biering, Scott B, Vance, Russell E, Harris, Eva

“…Dengue virus (DENV) is a medically important flavivirus causing an estimated 50-100 million dengue cases annually, some of whom progress to severe disease…”
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IS26-mediated formation of a virulence and resistance plasmid in Salmonella Enteritidis by Wong, Marcus Ho-Yin, Chan, Edward Wai-Chi, Chen, Sheng

“…To characterize a novel virulence-resistance plasmid pSE380T carried by a Salmonella enterica serotype Enteritidis clinical strain SE380. The plasmid pSE380T…”
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Evolution and dissemination of OqxAB-like efflux pumps, an emerging quinolone resistance determinant among members of Enterobacteriaceae by Wong, Marcus Ho Yin, Chan, Edward Wai Chi, Chen, Sheng

“…The OqxAB efflux pump, a plasmid-mediated quinolone resistance (PMQR) determinant, has become increasingly prevalent among members of Enterobacteriaceae over…”
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First Detection of AmpC β-Lactamase blaCMY-2 on a Conjugative IncA/C Plasmid in a Vibrio parahaemolyticus Isolate of Food Origin by Li, Ruichao, Lin, Dachuan, Chen, Kaichao, Wong, Marcus Ho Yin, Chen, Sheng

“…Vibrio parahaemolyticus is an important causative agent of gastroenteritis, with the consumption of contaminated seafood being the major transmission route…”
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Chlorogenic Acid Exhibits Cholesterol Lowering and Fatty Liver Attenuating Properties by Up-regulating the Gene Expression of PPAR-α in Hypercholesterolemic Rats Induced with a High-Cholesterol Diet by Wan, Chun-Wai, Wong, Candy Ngai-Yan, Pin, Wing-Kwan, Wong, Marcus Ho-Yin, Kwok, Ching-Yee, Chan, Robbie Yat-Kan, Yu, Peter Hoi-Fu, Chan, Shun-Wan

“…Hypercholesterolemia is a major risk factor for the development of cardiovascular disease and nonalcoholic fatty liver disease. Natural compounds have been…”
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Grapevine waste in sustainable hybrid particleboard production by Wong, Marcus C., Hendrikse, Simone I.S., Sherrell, Peter C., Ellis, Amanda V.

“…[Display omitted] •Hybrid particleboards with mixed cores of grapevine and pine were fabricated.•10% grapevine/90% pine particleboards passed all global…”
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Over-Expression of ISAba1-Linked Intrinsic and Exogenously Acquired OXA Type Carbapenem-Hydrolyzing-Class D-ß-Lactamase-Encoding Genes Is Key Mechanism Underlying Carbapenem Resistance in Acinetobacter baumannii by Wong, Marcus Ho-yin, Chan, Bill Kwan-wai, Chan, Edward Wai-chi, Chen, Sheng

“…Acinetobacter baumannii is an important clinical pathogen which often causes fatal infections among seriously ill patients. Treatment options for managing…”
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Molecular Determinants of Tissue Specificity of Flavivirus Nonstructural Protein 1 Interaction with Endothelial Cells by Lo, Nicholas T N, Roodsari, Susan Z, Tin, Nicole L, Wong, Marcus P, Biering, Scott B, Harris, Eva

“…Members of the mosquito-borne flavivirus genus such as dengue (DENV), West Nile (WNV), and Zika (ZIKV) viruses cause distinct diseases and affect different…”
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Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction by Biering, Scott B, Akey, David L, Wong, Marcus P, Brown, W Clay, Lo, Nicholas T N, Puerta-Guardo, Henry, Tramontini Gomes de Sousa, Francielle, Wang, Chunling, Konwerski, Jamie R, Espinosa, Diego A, Bockhaus, Nicholas J, Glasner, Dustin R, Li, Jeffrey, Blanc, Sophie F, Juan, Evan Y, Elledge, Stephen J, Mina, Michael J, Beatty, P Robert, Smith, Janet L, Harris, Eva

“…Medically important flaviviruses cause diverse disease pathologies and collectively are responsible for a major global disease burden. A contributing factor to…”
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Human immunodeficiency virus type-1 (HIV-1) evades antibody-dependent phagocytosis by Gach, Johannes S, Bouzin, Margaux, Wong, Marcus P, Chromikova, Veronika, Gorlani, Andrea, Yu, Kuan-Ting, Sharma, Brijesh, Gratton, Enrico, Forthal, Donald N

“…Fc gamma receptor (FcyR)-mediated antibody functions play a crucial role in preventing HIV infection. One such function, antibody-dependent phagocytosis (ADP),…”
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Organophosphate pesticide exposure and risk of SARS-CoV-2 infection by Lopez, Luis, Kogut, Katie, Rauch, Stephen, Gunier, Robert B., Wong, Marcus P., Harris, Eva, Deardorff, Julianna, Eskenazi, Brenda, Harley, Kim G.

“…Several studies have reported immune modulation by organophosphate (OP) pesticides, but the relationship between OP exposure and SARS-CoV-2 infection is yet to…”
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IncHI2 Plasmids Are the Key Vectors Responsible for oqxAB Transmission among Salmonella Species by Wong, Marcus Ho-Yin, Chan, Edward Wai-Chi, Xie, Liqi, Li, Ruichao, Chen, Sheng

“…This study reported and analyzed the complete sequences of two oqxAB-bearing IncHI2 plasmids harbored by a clinical Salmonella enterica serovar Typhimurium…”
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Prevalence and Clinical Profile of Severe Acute Respiratory Syndrome Coronavirus 2 Infection among Farmworkers, California, USA, June-November 2020 by Lewnard, Joseph A, Mora, Ana M, Nkwocha, Oguchi, Kogut, Katherine, Rauch, Stephen A, Morga, Norma, Hernandez, Samantha, Wong, Marcus P, Huen, Karen, Andrejko, Kristin, Jewell, Nicholas P, Parra, Kimberly L, Holland, Nina, Harris, Eva, Cuevas, Maximiliano, Eskenazi, Brenda

“…During the ongoing coronavirus disease (COVID-19) pandemic, farmworkers in the United States are considered essential personnel and continue in-person work. We…”
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Dissemination of IncI2 Plasmids That Harbor the blaCTX-M Element among Clinical Salmonella Isolates by Wong, Marcus Ho-Yin, Liu, Lizhang, Yan, Meiying, Chan, Edward Wai-Chi, Chen, Sheng

“…The extended-spectrum-β-lactamase (ESBL) determinant CTX-M-55 is increasingly prevalent in Escherichia coli but remains extremely rare in Salmonella. This…”
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PMQR genes oqxAB and aac(6')Ib-cr accelerate the development of fluoroquinolone resistance in Salmonella typhimurium by Wong, Marcus H, Chan, Edward W, Liu, Li Z, Chen, Sheng

“…Emergence of multidrug-resistant Salmonella typhimurium strains, especially the ACSSuT and nalidixic acid R types, has significantly compromised the…”
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Active maintenance of proton motive force mediates starvation-induced bacterial antibiotic tolerance in Escherichia coli by Wang, Miaomiao, Chan, Edward Wai Chi, Wan, Yingkun, Wong, Marcus Ho-yin, Chen, Sheng

“…Recent evidence suggests that metabolic shutdown alone does not fully explain how bacteria exhibit phenotypic antibiotic tolerance. In an attempt to…”
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SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling by Biering, Scott B., Gomes de Sousa, Francielle Tramontini, Tjang, Laurentia V., Pahmeier, Felix, Zhu, Chi, Ruan, Richard, Blanc, Sophie F., Patel, Trishna S., Worthington, Caroline M., Glasner, Dustin R., Castillo-Rojas, Bryan, Servellita, Venice, Lo, Nicholas T. N., Wong, Marcus P., Warnes, Colin M., Sandoval, Daniel R., Clausen, Thomas Mandel, Santos, Yale A., Fox, Douglas M., Ortega, Victoria, Näär, Anders M., Baric, Ralph S., Stanley, Sarah A., Aguilar, Hector C., Esko, Jeffrey D., Chiu, Charles Y., Pak, John E., Beatty, P. Robert, Harris, Eva

“…Severe COVID-19 is associated with epithelial and endothelial barrier dysfunction within the lung as well as in distal organs. While it is appreciated that an…”
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