Search Results - "Wong, Kin Fung"

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  1. 1

    Biogenic nanobubbles for effective oxygen delivery and enhanced photodynamic therapy of cancer by Song, Lin, Wang, Guohao, Hou, Xuandi, Kala, Shashwati, Qiu, Zhihai, Wong, Kin Fung, Cao, Fei, Sun, Lei

    Published in Acta biomaterialia (01-05-2020)
    “…Tumor hypoxia is believed to be a factor limiting successful outcomes of oxygen-consuming cancer therapy, thereby reducing patient survival. A key strategy to…”
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    Journal Article
  2. 2

    Behavioral and Functional Assessment of Ultrasound Neuromodulation on Caenorhabditis Elegans by Xian, Quanxiang, Qiu, Zhihai, Kala, Shashwati, Wong, Kin Fung, Guo, Jinghui, Sun, Lei

    “…Ultrasound brain stimulation is a promising modality for probing brain function and treating brain diseases. However, its mechanism is as yet unclear, and in…”
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  3. 3

    Nanobubble-actuated ultrasound neuromodulation for selectively shaping behavior in mice by Hou, Xuandi, Jing, Jianing, Jiang, Yizhou, Huang, Xiaohui, Xian, Quanxiang, Lei, Ting, Zhu, Jiejun, Wong, Kin Fung, Zhao, Xinyi, Su, Min, Li, Danni, Liu, Langzhou, Qiu, Zhihai, Sun, Lei

    Published in Nature communications (13-03-2024)
    “…Ultrasound is an acoustic wave which can noninvasively penetrate the skull to deep brain regions, enabling neuromodulation. However, conventional ultrasound’s…”
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  4. 4

    Precise Ultrasound Neuromodulation in a Deep Brain Region Using Nano Gas Vesicles as Actuators by Hou, Xuandi, Qiu, Zhihai, Xian, Quanxiang, Kala, Shashwati, Jing, Jianing, Wong, Kin Fung, Zhu, Jiejun, Guo, Jinghui, Zhu, Ting, Yang, Minyi, Sun, Lei

    Published in Advanced science (01-11-2021)
    “…Ultrasound is a promising new modality for non‐invasive neuromodulation. Applied transcranially, it can be focused down to the millimeter or centimeter range…”
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    Journal Article
  5. 5

    The mechanosensitive ion channel Piezo1 modulates the migration and immune response of microglia by Zhu, Ting, Guo, Jinghui, Wu, Yong, Lei, Ting, Zhu, Jiejun, Chen, Hui, Kala, Shashwati, Wong, Kin Fung, Cheung, Chi Pong, Huang, Xiaohui, Zhao, Xinyi, Yang, Minyi, Sun, Lei

    Published in iScience (17-02-2023)
    “…Microglia are the brain’s resident immune cells, performing surveillance to promote homeostasis and healthy functioning. While microglial chemical signaling is…”
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  6. 6

    Photonic Nanojet‐Mediated Optogenetics by Guo, Jinghui, Wu, Yong, Gong, Zhiyong, Chen, Xixi, Cao, Fei, Kala, Shashwati, Qiu, Zhihai, Zhao, Xinyi, Chen, Jun‐jiang, He, Dongming, Chen, Taiheng, Zeng, Rui, Zhu, Jiejun, Wong, Kin Fung, Murugappan, Suresh, Zhu, Ting, Xian, Quanxiang, Hou, Xuandi, Ruan, Ye Chun, Li, Baojun, Li, Yu Chao, Zhang, Yao, Sun, Lei

    Published in Advanced science (01-04-2022)
    “…Optogenetics has become a widely used technique in neuroscience research, capable of controlling neuronal activity with high spatiotemporal precision and…”
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    Journal Article
  7. 7

    Metformin accelerates zebrafish heart regeneration by inducing autophagy by Xie, Fangjing, Xu, Shisan, Lu, Yingying, Wong, Kin Fung, Sun, Lei, Hasan, Kazi Md Mahmudul, Ma, Alvin C. H., Tse, Gary, Manno, Sinai H. C., Tian, Li, Yue, Jianbo, Cheng, Shuk Han

    Published in npj Regenerative medicine (08-10-2021)
    “…Metformin is one of the most widely used drugs for type 2 diabetes and it also exhibits cardiovascular protective activity. However, the underlying mechanism…”
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  8. 8
  9. 9

    Protocol for the sonogenetic stimulation of mouse brain by non-invasive ultrasound by Xian, Quanxiang, Qiu, Zhihai, Kala, Shashwati, Guo, Jinghui, Zhu, Jiejun, Wong, Kin Fung, Guo, Sean Shu Yi, Zhu, Ting, Hou, Xuandi, Sun, Lei

    Published in STAR protocols (18-06-2021)
    “…Manipulating specific neural activity by targeted ultrasound intervention is a powerful method to gain causal insight into brain functions and treat brain…”
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    Journal Article
  10. 10

    Surface-modified GVs as nanosized contrast agents for molecular ultrasound imaging of tumor by Wang, Guohao, Song, Lin, Hou, Xuandi, Kala, Shashwati, Wong, Kin Fung, Tang, Liya, Dai, Yunlu, Sun, Lei

    Published in Biomaterials (01-04-2020)
    “…Nanobubbles, as a kind of new ultrasound contrast agent (UCAs), have shown promise to penetrate tumor vasculature to allow for targeted imaging. However, their…”
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  11. 11

    The mechanosensitive ion channel Piezo1 contributes to ultrasound neuromodulation by Zhu, Jiejun, Xian, Quanxiang, Hou, Xuandi, Wong, Kin Fung, Zhu, Tingting, Chen, Zihao, He, Dongming, Kala, Shashwati, Murugappan, Suresh, Jing, Jianing, Wu, Yong, Zhao, Xinyi, Li, Danni, Guo, Jinghui, Qiu, Zhihai, Sun, Lei

    “…Transcranial low-intensity ultrasound is a promising neuromodulation modality, with the advantages of noninvasiveness, deep penetration, and high…”
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  12. 12

    Targeted Neurostimulation in Mouse Brains with Non-invasive Ultrasound by Qiu, Zhihai, Kala, Shashwati, Guo, Jinghui, Xian, Quanxiang, Zhu, Jiejun, Zhu, Ting, Hou, Xuandi, Wong, Kin Fung, Yang, Minyi, Wang, Haoru, Sun, Lei

    Published in Cell reports (Cambridge) (18-08-2020)
    “…Recently developed brain stimulation techniques have significantly advanced our ability to manipulate the brain’s function. However, stimulating specific…”
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  13. 13

    Gas-filled protein nanostructures as cavitation nuclei for molecule-specific sonodynamic therapy by Song, Lin, Hou, Xuandi, Wong, Kin Fung, Yang, Yaoheng, Qiu, Zhihai, Wu, Yong, Hou, Shang, Fei, Chunlong, Guo, Jinghui, Sun, Lei

    Published in Acta biomaterialia (01-12-2021)
    “…Sonodynamic therapy (SDT) is a promising alternative for cancer therapy, understood to exert cytotoxicity through cavitation and subsequent production of large…”
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  14. 14

    Activation of N-Methyl-D-aspartate receptor contributed to the ultrasonic modulation of neurons in vitro by Yong, Wu, He, Dongming, Chen, Taiheng, Rui, Zeng, Wen, Yinchuan, Wong, Kin Fung, Sun, Lei, Qi, Xiaofei, Guo, Jinghui

    “…Ultrasound stimulation is increasingly used to investigate brain function and treat brain diseases due to its high level of safety and precise spatiotemporal…”
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  15. 15

    Modulation of deep neural circuits with sonogenetics by Xian, Quanxiang, Qiu, Zhihai, Murugappan, Suresh, Kala, Shashwati, Wong, Kin Fung, Li, Danni, Li, Guofeng, Jiang, Yizhou, Wu, Yong, Su, Min, Hou, Xuandi, Zhu, Jiejun, Guo, Jinghui, Qiu, Weibao, Sun, Lei

    “…Noninvasive control of neuronal activity in the deep brain can be illuminating for probing brain function and treating dysfunctions. Here, we present a…”
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  16. 16
  17. 17

    Estrogen accelerates heart regeneration by promoting the inflammatory response in zebrafish by Xu, Shisan, Xie, Fangjing, Tian, Li, Fallah, Samane, Babaei, Fatemeh, Manno, Sinai H C, Manno, Francis A M, Zhu, Lina, Wong, Kin Fung, Liang, Yimin, Ramalingam, Rajkumar, Sun, Lei, Wang, Xin, Plumb, Robert, Gethings, Lee, Lam, Yun Wah, Cheng, Shuk Han

    Published in Journal of endocrinology (01-04-2020)
    “…Sexual differences have been observed in the onset and prognosis of human cardiovascular diseases, but the underlying mechanisms are not clear. Here, we found…”
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