Search Results - "Wong, Kenny K."
-
1
Canadian Cardiovascular Society/Canadian Pediatric Cardiology Association Position Statement on Pulse Oximetry Screening in Newborns to Enhance Detection of Critical Congenital Heart Disease
Published in Canadian journal of cardiology (01-02-2017)“…Abstract Congenital heart disease is the most common congenital malformation and approximately 3 in 1000 newborns have critical congenital heart disease…”
Get full text
Journal Article -
2
From deinstitutionalization to recovery-oriented assertive community treatment in Hong Kong: What we have achieved
Published in Psychiatry research (30-08-2015)“…Abstract This paper explored the effectiveness of Assertive Community Treatment (ACT) for severely ill mental patients during a period of rapid…”
Get full text
Journal Article -
3
siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids[S]
Published in Journal of lipid research (01-06-2011)“…Increased serum apolipoprotein (apo)B and associated LDL levels are well-correlated with an increased risk of coronary disease. ApoE–/– and low density…”
Get full text
Journal Article -
4
Integrating siRNA and protein-protein interaction data to identify an expanded insulin signaling network
Published in Genome Research (01-06-2009)“…Insulin resistance is one of the dominant symptoms of type 2 diabetes (T2D). Although the molecular mechanisms leading to this resistance are largely unknown,…”
Get full text
Journal Article -
5
Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9[S]
Published in Journal of lipid research (01-04-2011)“…Reducing circulating LDL-cholesterol (LDL-c) reduces the risk of cardiovascular disease in people with hypercholesterolemia. Current approaches to reduce…”
Get full text
Journal Article -
6
Inverse relationship between LDL cholesterol and PCSK9 plasma levels in dyslipidemic cynomolgus monkeys: Effects of LDL lowering by ezetimibe in the absence of statins
Published in Atherosclerosis (01-11-2013)“…Abstract Objectives To assess the lipid-lowering efficacy of ezetimibe in dyslipidemic cynomolgus monkeys comparing two dosing methods, and to evaluate PCSK9…”
Get full text
Journal Article -
7
Trends in Pediatric Cardiology Referrals, Testing, and Satisfaction at a Canadian Tertiary Centre
Published in Canadian journal of cardiology (2015)“…Abstract Anecdotal and European evidence suggests that outpatient pediatric referrals and their diagnostic testing burden are increasing. We sought to…”
Get full text
Journal Article -
8
Quantifying apoprotein synthesis in rodents: coupling LC-MS/MS analyses with the administration of labeled water
Published in Journal of lipid research (01-06-2012)“…Stable isotope tracer studies of apoprotein flux in rodent models present difficulties as they require working with small volumes of plasma. We demonstrate the…”
Get full text
Journal Article -
9
Benign cardiac tumours, malignant arrhythmias
Published in Canadian journal of cardiology (01-02-2010)“…Four cases of pediatric cardiac tumours (PCTs) associated with ventricular arrhythmias are reported. Sudden cardiac death attributable to the tumour occurred…”
Get full text
Journal Article -
10
Inhibition of Cardiac Lipoprotein Utilization by Transgenic Overexpression of Angptl4 in the Heart
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-2005)“…To investigate the role of Angptl4, an inhibitor of lipoprotein lipase that is induced by >3-fold in the heart after rosiglitazone treatment, we generated…”
Get full text
Journal Article -
11
A genome-wide siRNA screen to identify modulators of insulin sensitivity and gluconeogenesis
Published in PloS one (09-05-2012)“…Hepatic insulin resistance impairs insulin's ability to suppress hepatic glucose production (HGP) and contributes to the development of type 2 diabetes (T2D)…”
Get full text
Journal Article -
12
Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered metabolic states
Published in Molecular pharmacology (01-08-2008)“…Adipose tissue is a metabolically responsive endocrine organ that secretes a myriad of adipokines. Antidiabetic drugs such as peroxisome proliferator-activated…”
Get more information
Journal Article -
13
Clinical Utility of Expanded Carrier Screening: Reproductive Behaviors of At-Risk Couples
Published in Journal of genetic counseling (01-06-2018)“…Expanded carrier screening (ECS) analyzes dozens or hundreds of recessive genes to determine reproductive risk. Data on the clinical utility of screening…”
Get full text
Journal Article -
14
Dietary exposure to polyaromatic hydrocarbons of the Hong Kong population
Published in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (02-08-2024)“…Polyaromatic hydrocarbons (PAHs) are ubiquitous in the environment and food. The Joint FAO/WHO Expert Committee on Food Additives concluded 13 individual PAHs…”
Get full text
Journal Article -
15
Long COVID-19: A Primer for Cardiovascular Health Professionals, on Behalf of the CCS Rapid Response Team
Published in Canadian journal of cardiology (01-08-2021)“…It is now widely recognized that COVID-19 illness can be associated with significant intermediate and potentially longer-term physical limitations. The term,…”
Get full text
Journal Article -
16
Systematic design and comparison of expanded carrier screening panels
Published in Genetics in medicine (01-01-2018)“…The recent growth in pan-ethnic expanded carrier screening (ECS) has raised questions about how such panels might be designed and evaluated systematically…”
Get full text
Journal Article -
17
Pulse oximetry screening in newborns to enhance detection of critical congenital heart disease
Published in Paediatrics & child health (01-11-2017)“…Abstract Pulse oximetry screening is safe, noninvasive, easy to perform and proven to enhance detection of critical congenital heart disease in newborns…”
Get full text
Journal Article -
18
Increased intracranial pressure in a patient with Congenital Heart Defect and Ectodermal Dysplasia (CHDED): Extension of phenotype and review of literature
Published in American journal of medical genetics. Part A (01-02-2023)“…Congenital heart defect (CHD) is a birth defect that affects the structure of the heart. Although CHD is often multifactorial, it can also be inherited as part…”
Get full text
Journal Article -
19
A Health Care Clinical Data Platform for Rapid Deployment of Artificial Intelligence and Machine Learning Algorithms for Cancer Care and Oncology Clinical Trials
Published in North Carolina medical journal (Durham, N.C.) (01-06-2024)“…The xCures platform aggregates, organizes, structures, and normalizes clinical EMR data across care sites, utilizing advanced technologies for near real-time…”
Get full text
Journal Article -
20
Preparing for CBME: How often are faculty observing residents?
Published in Paediatrics & child health (01-04-2021)“…Abstract Background The Royal College of Physicians and Surgeons of Canada officially launched ‘Competence by Design’ in July 2017, moving from time-based to…”
Get full text
Journal Article