Search Results - "Wong, Kah Keng"

Reduced occludin and claudin-7 expression is associated with urban locations and exposure to second-hand smoke in allergic rhinitis patients by Nur Husna, Siti Muhamad, Siti Sarah, Che Othman, Tan, Hern-Tze Tina, Md. Shukri, Norasnieda, Mohd Ashari, Noor Suryani, Wong, Kah Keng

“…The breakdown of nasal epithelial barrier occurs in allergic rhinitis (AR) patients. Impairment of cell junction molecules including tight junctions (TJs) and…”
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Th1, Th2, and Th17 cytokines in systemic lupus erythematosus by Muhammad Yusoff, Farhana, Wong, Kah Keng, Mohd Redzwan, Norhanani

“…Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the breakdown of immune tolerance leading to excessive inflammation and tissue…”
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TRPM4 is overexpressed in breast cancer associated with estrogen response and epithelial-mesenchymal transition gene sets by Wong, Kah Keng, Hussain, Faezahtul Arbaeyah

“…Ion channels form an important class of drug targets in malignancies. Transient receptor potential cation channel subfamily M member 4 (TRPM4) plays…”
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Thrombotic Management of Antiphospholipid Syndrome: Towards Novel Targeted Therapies by Islam, Md Asiful, Alam, Fahmida, Wong, Kah Keng, Kamal, Mohammad Amjad, Gan, Siew Hua

“…Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by thrombosis and/or pregnancy morbidity with persistent levels of…”
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Nasal Epithelial Barrier Integrity and Tight Junctions Disruption in Allergic Rhinitis: Overview and Pathogenic Insights by Nur Husna, Siti Muhamad, Tan, Hern-Tze Tina, Md Shukri, Norasnieda, Mohd Ashari, Noor Suryani, Wong, Kah Keng

“…Allergic rhinitis (AR) is a common disorder affecting up to 40% of the population worldwide and it usually persists throughout life. Nasal epithelial barrier…”
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Hypomethylating Agents and Immunotherapy: Therapeutic Synergism in Acute Myeloid Leukemia and Myelodysplastic Syndromes by Wong, Kah Keng, Hassan, Rosline, Yaacob, Nik Soriani

“…Decitabine and guadecitabine are hypomethylating agents (HMAs) that exert inhibitory effects against cancer cells. This includes stimulation of anti-tumor…”
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Oncogenic Roles and Inhibitors of DNMT1, DNMT3A, and DNMT3B in Acute Myeloid Leukaemia by Wong, Kah Keng, Lawrie, Charles H, Green, Tina M

“…Epigenetic alteration has been proposed to give rise to numerous classic hallmarks of cancer. Impaired DNA methylation plays a central role in the onset and…”
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Targeting dendritic cells through gold nanoparticles: A review on the cellular uptake and subsequent immunological properties by Ahmad, Suhana, Zamry, Anes Ateqah, Tan, Hern-Tze Tina, Wong, Kah Keng, Lim, JitKang, Mohamud, Rohimah

“…•Gold NPs as potential tool in immunotherapies due to their customizable size and shape, surface functionalization and unique optical properties.•Manipulation…”
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Work intensity and fat mass percentage are associated with asymptomatic morphometric vertebral fractures in knee osteoarthritis patients: A cross-sectional study by Zolkiply, Izzatul Nadiah, Wong, Kah Keng, Mohammad Sallehudin, Hakimah, Bidin, Mohammad Zulkarnain, Che Hamzah, Fahrudin, Bahari, Norafida, Wan Ghazali, Wan Syamimee

“…Knee osteoarthritis (OA) is a common condition with a prevalence of 365 million individuals globally, and it is an independent risk factor for falls and…”
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Allergic Rhinitis: A Clinical and Pathophysiological Overview by Nur Husna, Siti Muhamad, Tan, Hern-Tze Tina, Md Shukri, Norasnieda, Mohd Ashari, Noor Suryani, Wong, Kah Keng

“…Allergic rhinitis (AR) represents a global health concern where it affects approximately 400 million people worldwide. The prevalence of AR has increased over…”
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Editorial: A new frontier for traditional medicine research-Multi-omics approaches by Fu, Xianjun, Wong, Kah Keng, Tseng, Yiider

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Strobilanthes crispus elicits anti-tumor immunogenicity in in vitro and in vivo metastatic breast carcinoma by Baraya, Yusha'u Shu'aibu, Wee, Chee Lee, Mustapha, Zulkarnain, Wong, Kah Keng, Yaacob, Nik Soriani

“…Plant-based anticancer agents have the potential to stimulate the immune system to act against cancer cells. A standardized bioactive subfraction of the…”
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The oncogenic roles of TRPM ion channels in cancer by Wong, Kah Keng, Banham, Alison H., Yaacob, Nik Soriani, Nur Husna, Siti Muhamad

“…Transient receptor potential (TRP) proteins are a diverse family of ion channels present in multiple types of tissues. They function as gatekeepers for…”
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Cell Cycle Modulation of MCF-7 and MDA-MB-231 by a Sub-Fraction of Strobilanthes crispus and its Combination with Tamoxifen by Yaacob, Nik Soriani, Kamal, Nik Nursyazni Nik Mohamed, Wong, Kah Keng, Norazmi, Mohd Nor

“…Background: Cell cycle regulatory proteins are suitable targets for cancer therapeutic development since genetic alterations in many cancers also affect the…”
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IL-4/IL-13 axis as therapeutic targets in allergic rhinitis and asthma by Nur Husna, Siti Muhamad, Md Shukri, Norasnieda, Mohd Ashari, Noor Suryani, Wong, Kah Keng

“…Allergic rhinitis (AR) is a common disorder of the upper airway, while asthma is a disease affecting the lower airway and both diseases are usually comorbid…”
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Gold nanoparticles conjugated with anti-CD133 monoclonal antibody and 5-fluorouracil chemotherapeutic agent as nanocarriers for cancer cell targeting by Mohd-Zahid, Manali Haniti, Zulkifli, Siti Nadiah, Che Abdullah, Che Azurahanim, Lim, JitKang, Fakurazi, Sharida, Wong, Kah Keng, Zakaria, Andee Dzulkarnaen, Ismail, Norzila, Uskokovi, Vuk, Mohamud, Rohimah, A, Iskandar

“…The enhanced permeability and retention effect allows for passive targeting of solid tumours by nanoparticles carrying anticancer drugs. However, active…”
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Zonula occludens and nasal epithelial barrier integrity in allergic rhinitis by Siti Sarah, Che Othman, Md Shukri, Norasnieda, Mohd Ashari, Noor Suryani, Wong, Kah Keng

“…Allergic rhinitis (AR) is a common disease affecting 400 million of the population worldwide. Nasal epithelial cells form a barrier against the invasion of…”
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Cancer/testis antigen SPATA19 is frequently expressed in benign prostatic hyperplasia and prostate cancer by Wong, Kah Keng, Hussain, Faezahtul Arbaeyah, Loo, Suet Kee, López, José I.

“…Spermatogenesis‐associated 19 (SPATA19) is a cancer/testis antigen overexpressed in various cancers. However, its protein expression profile in malignant or…”
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Phylogenetic Tree Analysis of the Cold-Hot Nature of Traditional Chinese Marine Medicine for Possible Anticancer Activity by Wang, Zhenguo, Zhang, Fengcong, Li, Jiaoyang, Wong, Kah Keng, Li, Xuebo, Song, Xuxia, Fu, Xianjun, Wang, Changyun

“…Traditional Chinese Marine Medicine (TCMM) represents one of the medicinal resources for research and development of novel anticancer drugs. In this study, to…”
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Increased IL-23R+ Th Cells Population Exhibits Higher SLEDAI-2K Scores in Systemic Lupus Erythematosus Patients by Izati, Aziz Farah, Mohd Shukri, Nur Diyana, Wan Ghazali, Wan Syamimee, Che Hussin, Che Maraina, Wong, Kah Keng

“…The IL-23/IL-17 axis plays causative roles in the development and progression of systemic lupus erythematosus (SLE). However, it remains unclear if the IL-17RA…”
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