Search Results - "Wong, John Y.F"
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Neurochemical changes in dopamine D1, D3 and D1/D3 receptor knockout mice
Published in European journal of pharmacology (04-07-2003)“…Neurochemical changes were examined in dopamine D1 receptor knockout (D1 −/−), dopamine D3 receptor knockout (D3 −/−) and dopamine D1/D3 receptor double…”
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Proconvulsant-induced seizures in α4 nicotinic acetylcholine receptor subunit knockout mice
Published in Neuropharmacology (01-07-2002)Get full text
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Activated Macrophages and Microglia Induce Dopaminergic Sprouting in the Injured Striatum and Express Brain-Derived Neurotrophic Factor and Glial Cell Line-Derived Neurotrophic Factor
Published in The Journal of neuroscience (01-03-1999)“…Nigrostriatal dopaminergic neurons undergo sprouting around the margins of a striatal wound. The mechanism of this periwound sprouting has been unclear. In…”
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Phenotypic Characterization of an α4 Neuronal Nicotinic Acetylcholine Receptor Subunit Knock-Out Mouse
Published in The Journal of neuroscience (01-09-2000)“…Neuronal nicotinic acetylcholine receptors (nAChR) are present in high abundance in the nervous system ( Decker et al., 1995 ). There are a large number of…”
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Essential conservation of D1 mutant phenotype at the level of individual topographies of behaviour in mice lacking both D1 and D3 dopamine receptors
Published in Psychopharmacologia (01-05-2003)“…In the absence of agonists and antagonists evidencing appropriate selectivities, individual and interactive properties of D(1) and D(3) dopamine receptors…”
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Targeted Expression of a Toxin Gene to D1 Dopamine Receptor Neurons by Cre-Mediated Site-Specific Recombination
Published in The Journal of neuroscience (01-12-1998)“…Idiopathic Parkinson's disease involves the loss of midbrain dopaminergic neurons, resulting in the presynaptic breakdown of dopaminergic transmission in the…”
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Effect of Chronic Angiotensin‐Converting Enzyme Inhibition on Striatal Dopamine Content in the MPTP‐Treated Mouse
Published in Journal of neurochemistry (01-07-1999)“…: We have previously shown that chronic treatment with the angiotensin‐converting enzyme inhibitor perindopril increased striatal dopamine levels by 2.5‐fold…”
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Proconvulsant-induced seizures in α 4 nicotinic acetylcholine receptor subunit knockout mice
Published in Neuropharmacology (2002)“…The genetic basis of a number of epilepsy syndromes has been identified but the precise mechanism whereby these mutations produce seizures is unknown. Three…”
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Dopaminergic responses to striatal damage
Published in Journal of the neurological sciences (01-07-1996)“…The improvements obtained by grafting dopamine-rich tissues into the striatum of patients with Parkinson's disease are generally attributed to production and…”
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Expression of glial cell line-derived neurotrophic factor (GDNF) mRNA following mechanical injury to mouse striatum
Published in Neuroreport (01-09-1997)Get full text
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Surgical damage stimulates proliferation of dopamine uptake sites in normal mouse brain
Published in Brain research (17-09-1993)“…To test the hypothesis that proliferation of host dopaminergic tissue in response to injury plays an important role in the response to intrastriatal grafting,…”
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Leukaemia inhibitory factor prevents injury induced proliferation of striatal dopamine uptake sites
Published in Neuroreport (02-10-1995)“…The injury associated with implantation of an inert gelatin matrix (gel foam) into normal mouse striatum induces a long-lived increase in binding of…”
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