Search Results - "Wong, Jin Huei"

Hypoculoside, a sphingoid base-like compound from Acremonium disrupts the membrane integrity of yeast cells by Alfatah, Mohammad, Wong, Jin Huei, Nge, Choy Eng, Kong, Kiat Whye, Low, Kia Ngee, Leong, Chung Yan, Crasta, Sharon, Munusamy, Madhaiyan, Chang, Amanda Mun Leng, Hoon, Shawn, Ng, Siew Bee, Kanagasundaram, Yoganathan, Arumugam, Prakash

“…We have isolated Hypoculoside, a new glycosidic amino alcohol lipid from the fungus Acremonium sp. F2434 belonging to the order Hypocreales and determined its…”
Get full text

TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae by Alfatah, Mohammad, Wong, Jin Huei, Krishnan, Vidhya Gomathi, Lee, Yong Cheow, Sin, Quan Feng, Goh, Corinna Jie Hui, Kong, Kiat Whye, Lee, Wei Ting, Lewis, Jacqueline, Hoon, Shawn, Arumugam, Prakash

“…Target of Rapamycin Complex 1 (TORC1) is a highly conserved eukaryotic protein complex that couples the presence of growth factors and nutrients in the…”
Get full text

Diethyl phthalate (DEP) perturbs nitrogen metabolism in Saccharomyces cerevisiae by Goh, Corinna Jie Hui, Cui, Liang, Wong, Jin Huei, Lewis, Jacqueline, Goh, Megan, Kong, Kiat Whye, Yang, Lay Kien, Alfatah, Mohammad, Kanagasundaram, Yoganathan, Hoon, Shawn, Arumugam, Prakash

“…Phthalates are ubiquitously used as plasticizers in various consumer care products. Diethyl phthalate (DEP), one of the main phthalates, elicits developmental…”
Get full text

Chemogenomic profiling in yeast reveals antifungal mode-of-action of polyene macrolactam auroramycin by Wong, Jin Huei, Alfatah, Mohammad, Kong, Kiat Whye, Hoon, Shawn, Yeo, Wan Lin, Ching, Kuan Chieh, Jie Hui Goh, Corinna, Zhang, Mingzi M, Lim, Yee Hwee, Wong, Fong Tian, Arumugam, Prakash

“…In this study, we report antifungal activity of auroramycin against Candida albicans, Candida tropicalis, and Cryptococcus neoformans. Auroramycin, a potent…”
Get full text

A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53 by Wong, Jin Huei, Alfatah, Mohammad, Sin, Mei Fang, Sim, Hong May, Verma, Chandra S, Lane, David P, Arumugam, Prakash

“…Protein-protein interactions (PPIs) are fundamental to the growth and survival of cells and serve as excellent targets to develop inhibitors of biological…”
Get full text

Correction: Chemogenomic profiling in yeast reveals antifungal mode-of-action of polyene macrolactam auroramycin by Wong, Jin Huei, Alfatah, Mohammad, Kong, Kiat Whye, Hoon, Shawn, Yeo, Wan Lin, Ching, Kuan Chieh, Goh, Corinna Jie Hui, Zhang, Mingzi M, Lim, Yee Hwee, Wong, Fong Tian, Arumugam, Prakash

“…[This corrects the article DOI: 10.1371/journal.pone.0218189.]…”
Get full text

Chemical-genetic interaction landscape of mono-(2-ethylhexyl)-phthalate using chemogenomic profiling in yeast by Alfatah, Mohammad, Wong, Jin Huei, Kong, Kiat Whye, Utama, Felix, Hoon, Shawn, Arumugam, Prakash

“…Integration of chemical-genetic interaction data with biological functions provides a mechanistic understanding of how toxic compounds affect cells…”
Get full text

Metabolism of glucose activates TORC1 through multiple mechanisms in Saccharomyces cerevisiae by Alfatah, Mohammad, Cui, Liang, Goh, Corinna Jie Hui, Cheng, Trishia Yi Ning, Zhang, Yizhong, Naaz, Arshia, Wong, Jin Huei, Lewis, Jacqueline, Poh, Wei Jie, Arumugam, Prakash

“…Target of Rapamycin Complex 1 (TORC1) is a conserved eukaryotic protein complex that links the presence of nutrients with cell growth. In Saccharomyces…”
Get full text

PP2ACdc55’s role in reductional chromosome segregation during achiasmate meiosis in budding yeast is independent of its FEAR function by Kerr, Gary W., Wong, Jin Huei, Arumugam, Prakash

“…PP2A Cdc55 is a highly conserved serine-threonine protein phosphatase that is involved in diverse cellular processes. In budding yeast, meiotic cells lacking…”
Get full text

Macrocyclization of an all- d linear α-helical peptide imparts cellular permeability by Kannan, Srinivasaraghavan, Aronica, Pietro G. A., Ng, Simon, Gek Lian, Dawn Thean, Frosi, Yuri, Chee, Sharon, Shimin, Jiang, Yuen, Tsz Ying, Sadruddin, Ahmad, Kaan, Hung Yi Kristal, Chandramohan, Arun, Wong, Jin Huei, Tan, Yaw Sing, Chang, Zi Wei, Ferrer-Gago, Fernando J., Arumugam, Prakash, Han, Yi, Chen, Shiying, Rénia, Laurent, Brown, Christopher J., Johannes, Charles W., Henry, Brian, Lane, David P., Sawyer, Tomi K., Verma, Chandra S., Partridge, Anthony W.

“…Peptide-based molecules hold great potential as targeted inhibitors of intracellular protein–protein interactions (PPIs). Indeed, the vast diversity of…”
Get full text

Correction to: Identification of pathways modulating vemurafenib resistance in melanoma cells via a genome-wide CRISPR/Cas9 screen by Goh, Corinna Jie Hui, Wong, Jin Huei, El Farran, Chadi, Tan, Ban Xiong, Coffill, Cynthia R, Loh, Yuin-Han, Lane, David, Arumugam, Prakash

Get full text

Genome-wide analysis of mRNAs associated with mouse peroxisomes by Yarmishyn, Aliaksandr A, Kremenskoy, Maksym, Batagov, Arsen O, Preuss, Axel, Wong, Jin Huei, Kurochkin, Igor V

“…RNA is often targeted to be localized to the specific subcellular compartments. Specific localization of mRNA is believed to be an important mechanism for…”
Get full text

Identification of pathways modulating vemurafenib resistance in melanoma cells via a genome-wide CRISPR/Cas9 screen by Goh, Corinna Jie Hui, Wong, Jin Huei, El Farran, Chadi, Tan, Ban Xiong, Coffill, Cynthia R, Loh, Yuin-Han, Lane, David, Arumugam, Prakash

“…Abstract Vemurafenib is a BRAF kinase inhibitor (BRAFi) that is used to treat melanoma patients harboring the constitutively active BRAF-V600E mutation…”
Get full text

Macrocyclization of an all-d linear α-helical peptide imparts cellular permeability† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc06383h by Kannan, Srinivasaraghavan, Aronica, Pietro G. A., Ng, Simon, Gek Lian, Dawn Thean, Frosi, Yuri, Chee, Sharon, Shimin, Jiang, Yuen, Tsz Ying, Sadruddin, Ahmad, Kaan, Hung Yi Kristal, Chandramohan, Arun, Wong, Jin Huei, Tan, Yaw Sing, Chang, Zi Wei, Ferrer-Gago, Fernando J., Arumugam, Prakash, Han, Yi, Chen, Shiying, Rénia, Laurent, Brown, Christopher J., Johannes, Charles W., Henry, Brian, Lane, David P., Sawyer, Tomi K., Verma, Chandra S., Partridge, Anthony W.

“…Peptide-based molecules hold great potential as targeted inhibitors of intracellular protein–protein interactions (PPIs). Peptide-based molecules hold great…”
Get full text

PP2A(Cdc55)'s role in reductional chromosome segregation during achiasmate meiosis in budding yeast is independent of its FEAR function by Kerr, Gary W, Wong, Jin Huei, Arumugam, Prakash

“…PP2A(Cdc55) is a highly conserved serine-threonine protein phosphatase that is involved in diverse cellular processes. In budding yeast, meiotic cells lacking…”
Get full text

Macrocyclization of an all- linear α-helical peptide imparts cellular permeability by Kannan, Srinivasaraghavan, Aronica, Pietro G. A, Ng, Simon, Gek Lian, Dawn Thean, Frosi, Yuri, Chee, Sharon, Shimin, Jiang, Yuen, Tsz Ying, Sadruddin, Ahmad, Kaan, Hung Yi Kristal, Chandramohan, Arun, Wong, Jin Huei, Tan, Yaw Sing, Chang, Zi Wei, Ferrer-Gago, Fernando J, Arumugam, Prakash, Han, Yi, Chen, Shiying, Rénia, Laurent, Brown, Christopher J, Johannes, Charles W, Henry, Brian, Lane, David P, Sawyer, Tomi K, Verma, Chandra S, Partridge, Anthony W

“…Peptide-based molecules hold great potential as targeted inhibitors of intracellular protein-protein interactions (PPIs). Indeed, the vast diversity of…”
Get full text