Search Results - "Wong, Jerelyn"
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PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy
Published in The Journal of clinical investigation (01-04-2018)“…Intralesional therapy with oncolytic viruses (OVs) leads to the activation of local and systemic immune pathways, which may present targets for further…”
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PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy
Published in The Journal of clinical investigation (01-11-2018)Get full text
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Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy
Published in Journal for immunotherapy of cancer (01-09-2022)“…BackgroundImmune checkpoint inhibitors (ICI) have radically changed cancer therapy, but most patients with cancer are unresponsive or relapse after treatment…”
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Multiplexed quantification of proteins and transcripts in single cells
Published in Nature biotechnology (01-10-2017)“…High-throughput quantification of protein and gene expression in single cells is achieved using DNA-barcoded antibodies. We present a tool to measure gene and…”
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Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells
Published in Cancer research (Chicago, Ill.) (15-08-2017)“…GITR is a T-cell costimulatory receptor that enhances cellular and humoral immunity. The agonist anti-mouse GITR antibody DTA-1 has demonstrated efficacy in…”
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Isolation and characterization of the activated B-cell factor 1 homolog in Caenorhabditis elegans
Published in Nucleic acids research (01-11-2001)“…Members of the basic helix-loop-helix (bHLH) family of transcription factors regulate a wide array of developmental processes in many cell types, including…”
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Characterization of a basic helix-loop-helix protein, ABF-1: nuclear localization, transcriptional properties, and interaction with Id-2
Published in DNA and cell biology (01-08-2001)“…The activated B-cell factor (ABF)-1 cDNA was initially isolated from Epstein-Barr virus (EBV)-infected B cells and codes for a DNA-binding protein belonging to…”
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