Search Results - "Wong, Jack"
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Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications
Published in Marine Drugs (14-08-2015)“…Chitosan is a natural polycationic linear polysaccharide derived from chitin. The low solubility of chitosan in neutral and alkaline solution limits its…”
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Marine Peptides: Bioactivities and Applications
Published in Marine Drugs (29-06-2015)“…Peptides are important bioactive natural products which are present in many marine species. These marine peptides have high potential nutraceutical and…”
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3
LncRNAs with miRNAs in regulation of gastric, liver, and colorectal cancers: updates in recent years
Published in Applied microbiology and biotechnology (01-06-2019)“…Long noncoding RNA (lncRNA) is a kind of RNAi molecule composed of hundreds to thousands of nucleotides. There are several major types of functional lncRNAs…”
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4
Induced endothelial cells from peripheral arterial disease patients and neonatal fibroblasts have comparable angiogenic properties
Published in PloS one (10-08-2021)“…Induced endothelial cells (iECs) generated from neonatal fibroblasts via transdifferentiation have been shown to have pro-angiogenic properties and are a…”
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Down‐regulation of TIMP2 by HIF‐1α/miR‐210/HIF‐3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma
Published in Hepatology (Baltimore, Md.) (01-08-2016)“…Cancer metastasis is a multistep process that involves a series of tumor‐stromal interaction, including extracellular matrix (ECM) remodeling, which requires a…”
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6
Diversity of potentially exploitable pharmacological activities of the highly prized edible medicinal fungus Antrodia camphorata
Published in Applied microbiology and biotechnology (01-10-2019)“…Antrodia camphorata , also known as A. cinnamomea , is a precious medicinal basidiomycete fungus endemic to Taiwan. This article summarizes the recent advances…”
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A comparison of the pro-angiogenic potential of human induced pluripotent stem cell derived endothelial cells and induced endothelial cells in a murine model of peripheral arterial disease
Published in International journal of cardiology (01-05-2017)“…Abstract Background Endothelial cells derived from human induced pluripotent stem cells (iPSC-ECs) promote angiogenesis, and more recently induced endothelial…”
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Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical trials
Published in Applied microbiology and biotechnology (01-06-2020)“…This article reviews mushrooms with anti-breast cancer activity. The mushrooms covered which are better known include the following: button mushroom Agaricus…”
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Marine natural products with anti-inflammatory activity
Published in Applied microbiology and biotechnology (01-02-2016)“…Chronic inflammation is believed to play crucial roles in the pathogenesis of various diseases. Several types of drugs are used to treat inflammatory…”
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Endocytic Pathways Downregulate the L1-type Cell Adhesion Molecule Neuroglian to Promote Dendrite Pruning in Drosophila
Published in Developmental cell (25-08-2014)“…Pruning of unnecessary axons and/or dendrites is crucial for maturation of the nervous system. However, little is known about cell adhesion molecules (CAMs)…”
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Therapeutic potentials of short interfering RNAs
Published in Applied microbiology and biotechnology (01-10-2017)“…Short interfering RNA (siRNA) is one of the members of the family of RNA interference (RNAi). Coupled with the RNA-induced silencing complex (RISC), siRNA is…”
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Cathelicidins: peptides with antimicrobial, immunomodulatory, anti-inflammatory, angiogenic, anticancer and procancer activities
Published in Current protein & peptide science (01-09-2013)“…The family of peptides designated as cathelicidins was identified over a decade ago. Cathelicidins have since gained increasing recognition, both as endogenous…”
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Marine lectins and their medicinal applications
Published in Applied microbiology and biotechnology (01-05-2015)“…Marine organisms have been extensively explored for the last several decades as potential sources of novel biologically active compounds, and extensive…”
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Drugs for Targeted Therapies of Alzheimer's Disease
Published in Current medicinal chemistry (01-01-2019)“…Alzheimer's disease (AD) is one type of neurodegenerative diseases, which is prevalent in the elderly. Beta-amyloid (Aβ) plaques and phosphorylated tau-induced…”
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Axon Death Pathways Converge on Axundead to Promote Functional and Structural Axon Disassembly
Published in Neuron (Cambridge, Mass.) (05-07-2017)“…Axon degeneration is a hallmark of neurodegenerative disease and neural injury. Axotomy activates an intrinsic pro-degenerative axon death signaling cascade…”
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Antiviral activities of whey proteins
Published in Applied microbiology and biotechnology (01-09-2015)“…Milk contains an array of proteins with useful bioactivities. Many milk proteins encompassing native or chemically modified casein, lactoferrin,…”
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Mannose Binding Lectin: A Potential Biomarker for Many Human Diseases
Published in Current medicinal chemistry (01-10-2016)“…The innate immune system plays a modulatory role in producing an inflammatory response during microbial infection and tissue regeneration. Mannose-binding…”
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A Ribonuclease Isolated from Wild Ganoderma Lucidum Suppressed Autophagy and Triggered Apoptosis in Colorectal Cancer Cells
Published in Frontiers in pharmacology (25-07-2016)“…The mushroom Ganoderma lucidum (G. lucidum) has been consumed in China as a medicine for promoting health and longevity for thousands of years. Due to its…”
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Recent progress in research on ribosome inactivating proteins
Published in Current protein & peptide science (01-02-2010)“…The intent of this article is to review recent literature on ribosome inactivating proteins (RIPs) including isolation and characterization of new RIPs,…”
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A review of defensins of diverse origins
Published in Current protein & peptide science (01-10-2007)“…Defensins are a family of peptides with potent antimicrobial activity. They are found in various organisms. The intent of this article is to review the…”
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