Search Results - "Wong, Gladys W"

Enforcement of γδ-lineage commitment by the pre–T-cell receptor in precursors with weak γδ-TCR signals by Zarin, Payam, Wong, Gladys W., Mohtashami, Mahmood, Wiest, David L., Zúñiga-Pflücker, Juan Carlos

“…Developing thymocytes bifurcate from a bipotent precursor into αβ- or γδ-lineage T cells. Considering this common origin and the fact that the T-cell receptor…”
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HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCRβ-selected mouse thymocytes by Wong, Gladys W., Knowles, Gisele C., Mak, Tak W., Ferrando, Adolfo A., Zúñiga-Pflücker, Juan Carlos

“…The developmental progression of immature thymocytes requires cooperative input from several pathways, with Notch signals playing an indispensable role at the…”
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Enforcement of gamma delta -lineage commitment by the pre-T-cell receptor in precursors with weak gamma delta -TCR signals by Zarin, Payam, Wong, Gladys W, Mohtashami, Mahmood, Wiest, David L, Zuniga-Pfluecker, Juan Carlos

“…Developing thymocytes bifurcate from a bipotent precursor into alpha beta - or ...-lineage T cells. Considering this common origin and the fact that the T-cell…”
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The TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specification by Coffey, Francis, Lee, Sang-Yun, Buus, Terkild B, Lauritsen, Jens-Peter Holst, Wong, Gladys W, Joachims, Michelle L, Thompson, Linda F, Zúñiga-Pflücker, Juan Carlos, Kappes, Dietmar J, Wiest, David L

“…Numerous studies indicate that γδ T cell receptor (γδTCR) expression alone does not reliably mark commitment of early thymic progenitors to the γδ fate. This…”
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γδ and αβ T cell lineage choice: Resolution by a stronger sense of being by Wong, Gladys W, Zúñiga-Pflücker, Juan Carlos

“…Abstract A common bipotent thymocyte precursor gives rise to both lineages of T cells, αβ and γδ. However, the cell intrinsic and extrinsic factors that…”
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Integration of T‐cell receptor, Notch and cytokine signals programs mouse γδ T‐cell effector differentiation by Zarin, Payam, In, Tracy SH, Chen, Edward LY, Singh, Jastaranpreet, Wong, Gladys W, Mohtashami, Mahmood, Wiest, David L, Anderson, Michele K, Zúñiga‐Pflücker, Juan Carlos

“…γδ T‐cells perform a wide range of tissue‐ and disease‐specific functions that are dependent on the effector cytokines produced by these cells. However, the…”
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Marked Induction of the Helix-Loop-Helix Protein Id3 Promotes the γδ T Cell Fate and Renders Their Functional Maturation Notch Independent by Lauritsen, Jens Peter Holst, Wong, Gladys W., Lee, Sang-Yun, Lefebvre, Juliette M., Ciofani, Maria, Rhodes, Michele, Kappes, Dietmar J., Zúñiga-Pflücker, Juan Carlos, Wiest, David L.

“…αβ and γδ T cells arise from a common thymocyte progenitor during development in the thymus. Emerging evidence suggests that the pre-T cell receptor (pre-TCR)…”
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Enforcement of [gamma][delta]-lineage commitment by the pre-T-cell receptor in precursors with weak [gamma][delta]-TCR signals by Zarin, Payam, Wong, Gladys W, Mohtashami, Mahmood, Wiest, David L, Zúñiga-Pflücker, Juan Carlos

“…Developing thymocytes bifurcate from a bipotent precursor into αβ- or ...-lineage T cells. Considering this common origin and the fact that the T-cell receptor…”
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I[sup3I and ab T cell lineage choice: Resolution by a stronger sense of being by Wong, Gladys W, Zuniga-Pfluecker, Juan Carlos

“…A common bipotent thymocyte precursor gives rise to both lineages of T cells, ab and I[sup3I. However, the cell intrinsic and extrinsic factors that influence…”
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Marked Induction of the Helix-Loop-Helix Protein Id3 Promotes the [gamma][delta] T Cell Fate and Renders Their Functional Maturation Notch Independent by Lauritsen, Jens Peter Holst, Wong, Gladys W, Lee, Sang-Yun, Lefebvre, Juliette M, Ciofani, Maria, Rhodes, Michele, Kappes, Dietmar J, Zúñiga-Pflücker, Juan Carlos, Wiest, David L

“…αβ and γδ T cells arise from a common thymocyte progenitor during development in the thymus. Emerging evidence suggests that the pre-T cell receptor (pre-TCR)…”
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Differential induction of Id3 signals lineage divergence, Notch-independent differentiation, and functional maturation of γδ T cells by Lauritsen, Jens Peter Holst, Wong, Gladys W., Lee, Sang-Yun, Lefebvre, Juliette M., Ciofani, Maria, Rhodes, Michele, Kappes, Dietmar J., Zúñiga-Pflücker, Juan Carlos, Wiest, David L.

“…αβ and γδ T-cells arise from a common thymocyte progenitor during development in the thymus. Emerging evidence suggests that the pre-T cell receptor (pre-TCR)…”
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gammadelta and alphabeta T cell lineage choice: resolution by a stronger sense of being by Wong, Gladys W, Zúñiga-Pflücker, Juan Carlos

“…A common bipotent thymocyte precursor gives rise to both lineages of T cells, alphabeta and gammadelta. However, the cell intrinsic and extrinsic factors that…”
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Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent by Lauritsen, Jens Peter Holst, Wong, Gladys W, Lee, Sang-Yun, Lefebvre, Juliette M, Ciofani, Maria, Rhodes, Michele, Kappes, Dietmar J, Zúñiga-Pflücker, Juan Carlos, Wiest, David L

“…alphabeta and gammadelta T cells arise from a common thymocyte progenitor during development in the thymus. Emerging evidence suggests that the pre-T cell…”
Get full text