Search Results - "Wong, Francisca Siu Yin"
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Potential role of Lycium barbarum polysaccharides in glaucoma management: evidence from preclinical in vivo studies
Published in Neural regeneration research (01-12-2023)“…In recent years, the pharmacological benefits of herbal extracts have been revisited for their potential neuroprotective effects in glaucoma. The…”
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Lycium barbarum glycopeptide promotes neuroprotection in ET-1 mediated retinal ganglion cell degeneration
Published in Journal of translational medicine (05-08-2024)“…Vascular dysregulation is one of the major risk factors of glaucoma, and endothelin-1 (ET-1) may have a role in the pathogenesis of vascular-related glaucoma…”
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Selective blue-filtering spectacle lens protected primary porcine RPE cells against light emitting diode-induced cell damage
Published in PloS one (24-05-2022)“…This study aimed to investigate whether use of a selective-blue-filtering (S-BF) lens can protect cultured primary porcine RPE cells against photo-irradiation…”
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Longitudinal outcomes of circumlimbal suture model-induced chronic ocular hypertension in Sprague-Dawley albino rats
Published in Graefe's archive for clinical and experimental ophthalmology (01-12-2020)“…Purpose To characterise longitudinal structural and functional changes in albino Sprague-Dawley rats following circumlimbal suture ocular hypertension (OHT)…”
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Lycium Barbarum Polysaccharides Rescue Neurodegeneration in an Acute Ocular Hypertension Rat Model Under Pre- and Posttreatment Conditions
Published in Investigative ophthalmology & visual science (01-05-2019)“…To investigate the posttreatment neuronal rescue effects of Lycium barbarum polysaccharides (LBP) in an acute ocular hypertensive (AOH) model. Intraocular…”
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Subclinical Decrease in Central Inner Retinal Activity Is Associated With Myopia Development in Children
Published in Investigative ophthalmology & visual science (01-08-2017)“…To investigate the characteristics of retinal electrophysiological activity in relation to early myopia development in children. Fifty-six children aged 6 to 9…”
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Lycium barbarum Polysaccharide Suppresses Expression of Fibrotic Proteins in Primary Human Corneal Fibroblasts
Published in Journal of clinical medicine (06-11-2020)“…(1) Objective: To study the anti-fibrotic effects of Lycium barbarum polysaccharides (LBP) on corneal stromal fibroblasts and assess LBP’s effect on cell…”
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Both non-coated and polyelectrolytically-coated intraocular collagen-alginate composite gels enhanced photoreceptor survival in retinal degeneration
Published in Biomaterials (01-02-2023)“…Treatments of vision-threatening retinal diseases are often hampered by drug delivery difficulties. Polyelectrolytically-coated alginate encapsulated-cell…”
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Long-Term Effects on Retinal Structure and Function in a Mouse Endothelin-1 Model of Retinal Ganglion Cell Degeneration
Published in Investigative ophthalmology & visual science (01-08-2023)“…To study the long-term effects of endothelin-1 (ET-1)-induced retinal pathologies in mouse, using clinically relevant tools. Adult C57BL/6 mice (7-9 weeks old)…”
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Injectable cell-encapsulating composite alginate-collagen platform with inducible termination switch for safer ocular drug delivery
Published in Biomaterials (01-05-2019)“…Effective retinal drug delivery remains a challenge for treating vision-threatening diseases. Encapsulated-cell therapy (ECT) can provide local drug delivery…”
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Posttreatment Intervention With Lycium Barbarum Polysaccharides is Neuroprotective in a Rat Model of Chronic Ocular Hypertension
Published in Investigative ophthalmology & visual science (01-11-2019)“…To investigate the neuroprotective effects of Lycium barbarum polysaccharides (LBP) against chronic ocular hypertension (OHT) in rats and to consider if…”
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Childhood exposure to constricted living space: a possible environmental threat for myopia development
Published in Ophthalmic & physiological optics (01-09-2017)“…Purpose People in Hong Kong generally live in a densely populated area and their homes are smaller compared with most other cities worldwide. Interestingly,…”
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13
Selective blue-filtering spectacle lens protected primary porcine RPE cells against light emitting diode-induced cell damage
Published in PloS one (01-01-2022)“…This study aimed to investigate whether use of a selective-blue-filtering (S-BF) lens can protect cultured primary porcine RPE cells against photo-irradiation…”
Get full text
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