Search Results - "Wong, EE Ming"

DNA methylation‐based biological aging and cancer risk and survival: Pooled analysis of seven prospective studies by Dugué, Pierre‐Antoine, Bassett, Julie K., Joo, JiHoon E., Jung, Chol‐Hee, Ming Wong, Ee, Moreno‐Betancur, Margarita, Schmidt, Daniel, Makalic, Enes, Li, Shuai, Severi, Gianluca, Hodge, Allison M., Buchanan, Daniel D., English, Dallas R., Hopper, John L., Southey, Melissa C., Giles, Graham G., Milne, Roger L.

“…The association between aging and cancer is complex. Recent studies have developed measures of biological aging based on DNA methylation and called them “age…”
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Epigenome-wide association study of short-term temperature fluctuations based on within-sibship analyses in Australian females by Wu, Yao, Xu, Rongbin, Li, Shanshan, Ming Wong, Ee, Southey, Melissa C., Hopper, John L., Abramson, Michael J., Li, Shuai, Guo, Yuming

“…•This is the first study to assess the epigenetic impact of short-term temperature fluctuations.•Significant changes in methylation levels in 14…”
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Residential surrounding greenness and DNA methylation: An epigenome-wide association study by Xu, Rongbin, Li, Shuai, Li, Shanshan, Wong, Ee Ming, Southey, Melissa C., Hopper, John L., Abramson, Michael J., Guo, Yuming

“…[Display omitted] •Greenspace was associated with DNA methylation of multiple human genome loci.•Those loci are mapped to many genes related to many human…”
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Wildfire-related PM2.5 and DNA methylation: An Australian twin and family study by Xu, Rongbin, Li, Shanshan, Wu, Yao, Yue, Xu, Wong, Ee Ming, Southey, Melissa C., Hopper, John L., Abramson, Michael J., Li, Shuai, Guo, Yuming

“…[Display omitted] •Wildfire PM2.5 was associated with DNA methylation of many human genome loci.•Those loci were mapped to 47 genes related to many human…”
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Smoking and blood DNA methylation: an epigenome-wide association study and assessment of reversibility by Dugué, Pierre-Antoine, Jung, Chol-Hee, Joo, Jihoon E, Wang, Xiaochuan, Wong, Ee Ming, Makalic, Enes, Schmidt, Daniel F, Baglietto, Laura, Severi, Gianluca, Southey, Melissa C, English, Dallas R, Giles, Graham G, Milne, Roger L

“…We conducted a genome-wide association study of blood DNA methylation and smoking, attempted replication of previously discovered associations, and assessed…”
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Detection of differentially methylated CpGs between tumour and adjacent benign cells in diagnostic prostate cancer samples by FitzGerald, Liesel M., Jung, Chol-hee, Wong, Ee Ming, Joo, JiHoon E., Bassett, Julie K., Dowty, James G., Wang, Xiaoyu, Dai, James Y., Stanford, Janet L., O’Callaghan, Neil, Nottle, Tim, Pedersen, John, Giles, Graham G., Southey, Melissa C.

“…Differentially methylated CpG sites (dmCpGs) that distinguish prostate tumour from adjacent benign tissue could aid in the diagnosis and prognosis of prostate…”
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Causal effect of smoking on DNA methylation in peripheral blood: a twin and family study by Li, Shuai, Wong, Ee Ming, Bui, Minh, Nguyen, Tuong L, Joo, Ji-Hoon Eric, Stone, Jennifer, Dite, Gillian S, Giles, Graham G, Saffery, Richard, Southey, Melissa C, Hopper, John L

“…Smoking has been reported to be associated with peripheral blood DNA methylation, but the causal aspects of the association have rarely been investigated. We…”
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VTRNA2-1 : Genetic Variation, Heritable Methylation and Disease Association by Dugué, Pierre-Antoine, Yu, Chenglong, McKay, Timothy, Wong, Ee Ming, Joo, Jihoon Eric, Tsimiklis, Helen, Hammet, Fleur, Mahmoodi, Maryam, Theys, Derrick, kConFab, Hopper, John L, Giles, Graham G, Milne, Roger L, Steen, Jason A, Dowty, James G, Nguyen-Dumont, Tu, Southey, Melissa C

“…is a metastable epiallele with accumulating evidence that methylation at this region is heritable, modifiable and associated with disease including risk and…”
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Does genetic predisposition modify the effect of lifestyle-related factors on DNA methylation? by Yu, Chenglong, Hodge, Allison M, Wong, Ee Ming, Joo, Jihoon E, Makalic, Enes, Schmidt, Daniel F, Buchanan, Daniel D, Severi, Gianluca, Hopper, John L, English, Dallas R, Giles, Graham G, Milne, Roger L, Southey, Melissa C, Dugué, Pierre-Antoine

“…Lifestyle-related phenotypes have been shown to be heritable and associated with DNA methylation. We aimed to investigate whether genetic predisposition to…”
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The utility of DNA extracted from saliva for genome-wide molecular research platforms by Bruinsma, Fiona J, Joo, Jihoon E, Wong, Ee Ming, Giles, Graham G, Southey, Melissa C

“…The study aimed to investigate the suitability of DNA extracted from saliva for high throughput molecular genotyping and DNA methylation platforms by comparing…”
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Early life affects late-life health through determining DNA methylation across the lifespan: A twin study by Li, Shuai, Ye, Zhoufeng, Mather, Karen A., Nguyen, Tuong L., Dite, Gillian S., Armstrong, Nicola J., Wong, Ee Ming, Thalamuthu, Anbupalam, Giles, Graham G., Craig, Jeffrey M., Saffery, Richard, Southey, Melissa C., Tan, Qihua, Sachdev, Perminder S., Hopper, John L.

“…Previous findings for the genetic and environmental contributions to DNA methylation variation were for limited age ranges only. We investigated the lifespan…”
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Methylation of Breast Cancer Predisposition Genes in Early-Onset Breast Cancer: Australian Breast Cancer Family Registry by Scott, Cameron M, Joo, JiHoon Eric, O'Callaghan, Neil, Buchanan, Daniel D, Clendenning, Mark, Giles, Graham G, Hopper, John L, Wong, Ee Ming, Southey, Melissa C

“…DNA methylation can mimic the effects of both germline and somatic mutations for cancer predisposition genes such as BRCA1 and p16INK4a. Constitutional DNA…”
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Repeatability of methylation measures using a QIAseq targeted methyl panel and comparison with the Illumina HumanMethylation450 assay by Yu, Chenglong, Dugué, Pierre-Antoine, Dowty, James G, Hammet, Fleur, Joo, JiHoon E, Wong, Ee Ming, Hosseinpour, Mahnaz, Giles, Graham G, Hopper, John L, Nguyen-Dumont, Tu, MacInnis, Robert J, Southey, Melissa C

“…In previous studies using Illumina Infinium methylation arrays, we have identified DNA methylation marks associated with cancer predisposition and progression…”
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Twin birth changes DNA methylation of subsequent siblings by Li, Shuai, Kim, Eunae, Wong, Ee Ming, Joo, Ji-Hoon Eric, Nguyen, Tuong L., Stone, Jennifer, Song, Yun-Mi, Flander, Louisa B., Saffery, Richard, Giles, Graham G., Southey, Melissa C., Sung, Joohon, Hopper, John L.

“…We asked if twin birth influences the DNA methylation of subsequent siblings. We measured whole blood methylation using the HumanMethylation450 array for…”
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Causes of blood methylomic variation for middle-aged women measured by the HumanMethylation450 array by Li, Shuai, Wong, Ee Ming, Nguyen, Tuong L., Joo, Ji-Hoon Eric, Stone, Jennifer, Dite, Gillian S., Giles, Graham G., Saffery, Richard, Southey, Melissa C., Hopper, John L.

“…To address the limitations in current classic twin/family research on the genetic and/or environmental causes of human methylomic variation, we measured blood…”
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Association of FOXO3 Blood DNA Methylation with Cancer Risk, Cancer Survival, and Mortality by Yu, Chenglong, Hodge, Allison M, Wong, Ee Ming, Joo, Jihoon Eric, Makalic, Enes, Schmidt, Daniel, Buchanan, Daniel D, Hopper, John L, Giles, Graham G, Southey, Melissa C, Dugué, Pierre-Antoine

“…Genetic variants in are associated with longevity. Here, we assessed whether blood DNA methylation at was associated with cancer risk, survival, and mortality…”
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Characterization of a RAD51C -silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance by Hurley, Rachel M, McGehee, Cordelia D, Nesic, Ksenija, Correia, Cristina, Weiskittel, Taylor M, Kelly, Rebecca L, Venkatachalam, Annapoorna, Hou, Xiaonan, Pathoulas, Nicholas M, Meng, X Wei, Kondrashova, Olga, Radke, Marc R, Schneider, Paula A, Flatten, Karen S, Peterson, Kevin L, Becker, Marc A, Wong, Ee Ming, Southey, Melissa S, Dobrovic, Alexander, Lin, Kevin K, Harding, Thomas C, McNeish, Iain, Ross, Christian A, Wagner, Jill M, Wakefield, Matthew J, Scott, Clare L, Haluska, Paul, Wahner Hendrickson, Andrea E, Karnitz, Larry M, Swisher, Elizabeth M, Li, Hu, Weroha, S John, Kaufmann, Scott H

“…Acquired PARP inhibitor (PARPi) resistance in - or -mutant ovarian cancer often results from secondary mutations that restore expression of functional protein…”
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Tools for translational epigenetic studies involving formalin-fixed paraffin-embedded human tissue: applying the Infinium HumanMethyation450 Beadchip assay to large population-based studies by Wong, Ee Ming, Joo, JiHoon E, McLean, Catriona A, Baglietto, Laura, English, Dallas R, Severi, Gianluca, Hopper, John L, Milne, Roger L, FitzGerald, Liesel M, Giles, Graham G, Southey, Melissa C

“…Large population-based translational epigenetic studies are emerging due to recent technological advances that have made molecular analyses possible. For…”
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Prediction of BRCA1 and BRCA2 mutation status using post-irradiation assays of lymphoblastoid cell lines is compromised by inter-cell-line phenotypic variability by LOVELOCK, Paul K, EE MING WONG, BROWN, Melissa A, CHENEVIX-TRENCH, Georgia, SPURDLE, Amanda B, MCKAY, Michael J, SPRUNG, Carl N, MARSH, Anna, HOBSON, Karen, FRENCH, Juliet D, SOUTHEY, Melissa, INVESTIGATORS, Kconfab, SCULLEY, Tom, PANDEYA, Nirmala

“…Assays to determine the pathogenicity of unclassified sequence variants in disease-associated genes include the analysis of lymphoblastoid cell lines (LCLs)…”
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Integrating DNA methylation measures to improve clinical risk assessment: are we there yet? The case of BRCA1 methylation marks to improve clinical risk assessment of breast cancer by Wong, Ee Ming, Southey, Melissa C., Terry, Mary Beth

“…Current risk prediction models estimate the probability of developing breast cancer over a defined period based on information such as family history,…”
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