Search Results - "Wong, Chin Piow"
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Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood
Published in Nature communications (17-01-2022)“…2-(2-Phenylethyl)chromones (PECs) are the principal constituents contributing to the distinctive fragrance of agarwood. How PECs are biosynthesized is…”
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2
Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3
Published in Angewandte Chemie International Edition (08-01-2018)“…The cyanobacterial prenyltransferase AmbP3 catalyzes the reverse prenylation of the tetracyclic indole alkaloid hapalindole U at its C‐2 position…”
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Umezawamides, new bioactive polycyclic tetramate macrolactams isolated from a combined-culture of Umezawaea sp. and mycolic acid-containing bacterium
Published in Journal of antibiotics (01-07-2018)“…New polycyclic tetramate macrolactams, Umezawamides A ( 1 ) and B ( 2 ) were isolated from a combined-culture of Umezawaea sp. RD066910 and mycolic-acid…”
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4
Cliniatines A–C, new Amaryllidaceae alkaloids from Clivia miniata, inhibiting Acetylcholinesterase
Published in Journal of natural medicines (01-01-2022)“…Cliniatines A–C ( 1 – 3 ), three new Amaryllidaceae alkaloids, consisting of 2,6-dimetylpyridine and lycorine-type and/or galanthamine-type were isolated from…”
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Two new quassinoids and other constituents from Picrasma javanica wood, and their biological activities
Published in Journal of natural medicines (01-06-2019)“…Picrasma javanica Blume (Simaroubaceae) is a medium-sized tree that is distributed widely in tropical Asia. In our previous study, we isolated quassinoids from…”
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Antimelanogenic Activity of Ocotillol‐Type Saponins from Panax vietnamensis
Published in Chemistry & biodiversity (01-05-2020)“…The ocotillol (OCT)‐type saponins have been known as a tetracyclic triterpenoid, possessing five‐ or six‐membered epoxy ring in the side chain. Interestingly,…”
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Ceramicines M–P from Chisocheton ceramicus: isolation and structure–activity relationship study
Published in Journal of natural medicines (01-01-2018)“…Ceramicines are a series of limonoids which were isolated from the bark of Malaysian Chisocheton ceramicus (Meliaceae) and show various biological activities…”
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Mirilactams C–E, Novel Polycyclic Macrolactams Isolated from Combined-Culture of Actinosynnema mirum NBRC 14064 and Mycolic Acid-Containing Bacterium
Published in Chemical & pharmaceutical bulletin (01-06-2018)“…Mycolic acid-containing bacteria (MACB) are known to activate cryptic natural product biosynthesis in co-cultures with actinobacteria. We cultured…”
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9
New cytotoxic polyacetylene alcohols from the Egyptian marine sponge Siphonochalina siphonella
Published in Journal of natural medicines (01-03-2020)“…Three new polyacetylenic alcohols, siphonellanols A–C ( 1 – 3 ), together with two known polyacetylenic alcohols ( 4 – 5 ), were isolated from the CHCl 3…”
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10
Walsogynes H–O from Walsura chrysogyne
Published in Journal of natural medicines (01-01-2022)“…Eight new limonoids, walsogynes H–O ( 1 – 8 ) were isolated from the barks of Walsura chrysogyne , and their structures were determined on the basis of the 1D…”
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Three new quassinoids isolated from the wood of Picrasma javanica and their anti-Vpr activities
Published in Journal of natural medicines (01-06-2020)“…Three new quassinoids, javanicinols A and B ( 1 and 2 ) and 4-keto-(16 S )-methoxyjavanicin B ( 3 ), together with three known quassinoids ( 4–6 ) were…”
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Reinereins A and B, new onocerane triterpenoids from Reinwardtiodendron cinereum
Published in Journal of natural medicines (01-03-2018)“…Bioactivity guided separation of Reinwardtiodendron cinereum barks methanol extract led to the isolation of two new onocerane triterpenoids, reinereins A and B…”
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13
How structural subtleties lead to molecular diversity for the type III polyketide synthases
Published in The Journal of biological chemistry (11-10-2019)“…Type III polyketide synthases (PKSs) produce an incredibly diverse group of plant specialized metabolites with medical importance despite their structural…”
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14
Plant natural products as an anti-lipid droplets accumulation agent
Published in Journal of natural medicines (01-04-2014)“…Recently people often suffer from unhealthy energy metabolism balance as they tend to take more energy than required. Normally, excess energy taken in is…”
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Anti-melanin deposition activity and active constituents of Jatropha multifida stems
Published in Journal of natural medicines (01-09-2019)“…Jatropha multifida is a medicinal plant that belongs to the Euphorbiaceae family. Our investigation revealed that the chloroform extract of J. multifida stems…”
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Sabiperones A-F, New Diterpenoids from Juniperus sabina
Published in Chemical & pharmaceutical bulletin (01-01-2012)“…Six new diterpenoids, sabiperones A-F (1-6) have been isolated from the aerial part of Juniperus sabina. Their structures were elucidated by spectroscopic…”
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Rupestines F-M, New Guaipyridine Sesquiterpene Alkaloids from Artemisia rupestris
Published in Chemical & pharmaceutical bulletin (2012)“…Eight new guaipyridine sesquiterpene alkaloids, rupestines F-M (1-8) were isolated from the leaves of Artemisia rupestris and their structures were elucidated…”
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Ceramicines E—I, New Limonoids from Chisocheton ceramicus
Published in Chemical & Pharmaceutical Bulletin (2011)“…Five new limonoids, ceramicines E—I (1—5), have been isolated from the bark of Chisocheton ceramicus. The structures and relative stereochemistry of them were…”
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Dysosesquiflorins A and B, sesquiterpenoids from Dysoxylum densiflorum
Published in Journal of natural medicines (01-07-2015)“…Two new aromadendrane sesquiterpenoids, dysosesquiflorins A and B ( 1 and 2 ), were isolated from Dysoxylum densiflorum bark, and their structures were…”
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Four new Amaryllidaceae alkaloids from Zephyranthes candida
Published in Journal of natural medicines (01-07-2014)“…Four new Amaryllidaceae alkaloids (1–4) possessing a homolycorine-type or a crinine-type skeleton have been isolated from the aerial part of Zephyranthes…”
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