Search Results - "Wong, C. T"

Examining the impact of digital technologies on students' higher education outcomes: the case of the virtual learning environment and social media by Lacka, Ewelina, Wong, T. C.

“…Digital natives is a term used to describe current higher education (HE) students, whose lives are proliferated by digital technologies. To cater to the needs…”
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MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription by Chahrour, Maria, Jung, Sung Yun, Shaw, Chad, Zhou, Xiaobo, Wong, Stephen T.C, Qin, Jun, Zoghbi, Huda Y

“…Mutations in the gene encoding the transcriptional repressor methyl-CpG binding protein 2 (MeCP2) cause the neurodevelopmental disorder Rett syndrome. Loss of…”
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Cellular and molecular processes in ovarian cancer metastasis. A Review in the Theme: Cell and Molecular Processes in Cancer Metastasis by Yeung, Tsz-Lun, Leung, Cecilia S, Yip, Kay-Pong, Au Yeung, Chi Lam, Wong, Stephen T C, Mok, Samuel C

“…Ovarian cancer is the most lethal gynecological malignancy. It is usually diagnosed at a late stage, with a 5-yr survival rate of <30%. The majority of ovarian…”
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Combining deep learning and coherent anti-Stokes Raman scattering imaging for automated differential diagnosis of lung cancer by Weng, Sheng, Xu, Xiaoyun, Li, Jiasong, Wong, Stephen T. C

“…Lung cancer is the most prevalent type of cancer and the leading cause of cancer-related deaths worldwide. Coherent anti-Stokes Raman scattering (CARS) is…”
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Decreased dopamine activity predicts relapse in methamphetamine abusers by Wang, G J, Smith, L, Volkow, N D, Telang, F, Logan, J, Tomasi, D, Wong, C T, Hoffman, W, Jayne, M, Alia-Klein, N, Thanos, P, Fowler, J S

“…Studies in methamphetamine (METH) abusers showed that the decreases in brain dopamine (DA) function might recover with protracted detoxification. However, the…”
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Computational Identification of MoRFs in Protein Sequences Using Hierarchical Application of Bayes Rule by Malhis, Nawar, Wong, Eric T C, Nassar, Roy, Gsponer, Jörg

“…Intrinsically disordered regions of proteins play an essential role in the regulation of various biological processes. Key to their regulatory function is…”
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Semi-supervised drug-protein interaction prediction from heterogeneous biological spaces by Xia, Zheng, Wu, Ling-Yun, Zhou, Xiaobo, Wong, Stephen T C

“…Predicting drug-protein interactions from heterogeneous biological data sources is a key step for in silico drug discovery. The difficulty of this prediction…”
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Modeling daily patient arrivals at Emergency Department and quantifying the relative importance of contributing variables using artificial neural network by Xu, M., Wong, T.C., Chin, K.S.

“…Emergency Department (ED) plays a critical role in healthcare systems by providing emergency care to patients in need. The quality of ED services, measured by…”
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Randomized clinical trial of hepatic resection versus radiofrequency ablation for early‐stage hepatocellular carcinoma by Ng, K. K. C., Chok, K. S. H., Chan, A. C. Y., Cheung, T. T., Wong, T. C. L., Fung, J. Y. Y., Yuen, J., Poon, R. T. P., Fan, S. T., Lo, C. M.

“…Background Hepatic resection and radiofrequency ablation (RFA) are treatment options for early‐stage hepatocellular carcinoma (HCC). Whether tumour recurrence…”
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Targeting ribosome biogenesis as a novel therapeutic approach to overcome EMT-related chemoresistance in breast cancer by Ban, Yi, Zou, Yue, Liu, Yingzhuo, Lee, Sharrel, Bednarczyk, Robert B, Sheng, Jianting, Cao, Yuliang, Wong, Stephen T C, Gao, Dingcheng

“…Epithelial-to-mesenchymal transition (EMT) contributes significantly to chemotherapy resistance and remains a critical challenge in treating advanced breast…”
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Bringing CLARITY to the human brain: visualization of Lewy pathology in three dimensions by Liu, A. K. L., Hurry, M. E. D., Ng, O.T. W., DeFelice, J., Lai, H. M., Pearce, R. K. B., Wong, G. T-C., Chang, R. C-C., Gentleman, S. M.

“…Aims CLARITY is a novel technique which enables three‐dimensional visualization of immunostained tissue for the study of circuitry and spatial interactions…”
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Statins reduce the risk of liver decompensation and death in chronic viral hepatitis: a propensity score weighted landmark analysis by Wong, J. C.‐T., Chan, H. L.‐Y., Tse, Y.‐K., Yip, T. C.‐F., Wong, V. W.‐S., Wong, G. L.‐H.

“…Summary Background Decompensated liver disease due to portal hypertension leads to significant morbidity and mortality. Statins can modulate intrahepatic…”
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Application of droplet digital PCR in minimal residual disease monitoring of rare fusion transcripts and mutations in haematological malignancies by Ip, Beca B. K., Wong, Anthony T. C., Law, Janet Hei Yin, Au, Chun Hang, Ma, Shing Yan, Chim, James C. S., Liang, Raymond H. S., Leung, Anskar Y. H., Wan, Thomas S. K., Ma, Edmond S. K.

“…Leukaemia of various subtypes are driven by distinct chromosomal rearrangement or genetic abnormalities. The leukaemogenic fusion transcripts or genetic…”
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On the importance of polar interactions for complexes containing intrinsically disordered proteins by Wong, Eric T C, Na, Dokyun, Gsponer, Jörg

“…There is a growing recognition for the importance of proteins with large intrinsically disordered (ID) segments in cell signaling and regulation. ID segments…”
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An AI-driven clinical care pathway to reduce 30-day readmission for chronic obstructive pulmonary disease (COPD) patients by Wang, Lin, Li, Guihua, Ezeana, Chika F., Ogunti, Richard, Puppala, Mamta, He, Tiancheng, Yu, Xiaohui, Wong, Solomon S. Y., Yin, Zheng, Roberts, Aaron W., Nezamabadi, Aryan, Xu, Pingyi, Frost, Adaani, Jackson, Robert E., Wong, Stephen T. C.

“…Healthcare regulatory agencies have mandated a reduction in 30-day hospital readmission rates and have targeted COPD as a major contributor to 30-day…”
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Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer's disease by Faridar, Alireza, Vasquez, Matthew, Thome, Aaron D, Yin, Zheng, Xuan, Hui, Wang, Jing Hong, Wen, Shixiang, Li, Xuping, Thonhoff, Jason R, Zhao, Weihua, Zhao, Hong, Beers, David R, Wong, Stephen T C, Masdeu, Joseph C, Appel, Stanley H

“…Regulatory T cells (Tregs) play a neuroprotective role by suppressing microglia and macrophage-mediated inflammation and modulating adaptive immune reactions…”
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Geriatric Nutritional Risk Index, a Simplified Nutritional Screening Index, Is a Strong Predictor of Handgrip Strength in Renal Transplant Recipients by Lin, I.-H., Wong, T.-C., Nien, S.-W., Wang, H.-H., Chiang, Y.-J., Yang, S.-H.

“…The Geriatric Nutritional Risk Index (GNRI) is a useful predictor of prognosis in older patients and those receiving hemodialysis. However, the predictive…”
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Medical teachers' experience of emergency remote teaching during the COVID-19 pandemic: a cross-institutional study by Chan, Enoch, Khong, Mei Li, Torda, Adrienne, Tanner, Julian A, Velan, Gary M, Wong, Gordon T C

“…The COVID-19 pandemic and the consequent social distancing measures caused unprecedented disruption for medical and healthcare education. This study examined…”
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Old Drug New Use―Amoxapine and Its Metabolites as Potent Bacterial β-Glucuronidase Inhibitors for Alleviating Cancer Drug Toxicity by REN KONG, LIU, Timothy, XIAOPING ZHU, AHMAD, Syed, WILLIAMS, Alfred L, PHAN, Alexandria T, HONG ZHAO, SCOTT, John E, YEH, Li-An, WONG, Stephen T. C

“…Irinotecan (CPT-11) induced diarrhea occurs frequently in patients with cancer and limits its usage. Bacteria β-glucuronidase (GUS) enzymes in intestines…”
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Remanufacturing: A potential sustainable solution for increasing medical equipment availability by Eze, Solomon, Ijomah, Winifred, Wong, T. C

“…The availability of medical equipment contributes significantly to the stability and sustainability of health care systems. However, in some countries,…”
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