Search Results - "Wong, C B"

Multi-species single-cell transcriptomic analysis of ocular compartment regulons by Gautam, Pradeep, Hamashima, Kiyofumi, Chen, Ying, Zeng, Yingying, Makovoz, Bar, Parikh, Bhav Harshad, Lee, Hsin Yee, Lau, Katherine Anne, Su, Xinyi, Wong, Raymond C. B., Chan, Woon-Khiong, Li, Hu, Blenkinsop, Timothy A., Loh, Yuin-Han

“…The retina is a widely profiled tissue in multiple species by single-cell RNA sequencing studies. However, integrative research of the retina across species is…”
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Drusen in patient-derived hiPSC-RPE models of macular dystrophies by Galloway, Chad A., Dalvi, Sonal, Hung, Sandy S. C., MacDonald, Leslie A., Latchney, Lisa R., Wong, Raymond C. B., Guymer, Robyn H., Mackey, David A., Williams, David S., Chung, Mina M., Gamm, David M., Pébay, Alice, Hewitt, Alex W., Singh, Ruchira

“…Age-related macular degeneration (AMD) and related macular dystrophies (MDs) are a major cause of vision loss. However, the mechanisms underlying their…”
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Author Correction: NMNAT2 is a druggable target to drive neuronal NAD production by Tribble, James R., Jöe, Melissa, Varricchio, Carmine, Otmani, Amin, Canovai, Alessio, Habchi, Baninia, Daskalakis, Evangelia, Chaleckis, Romanas, Loreto, Andrea, Gilley, Jonathan, Wheelock, Craig E., Jóhannesson, Gauti, Wong, Raymond C. B., Coleman, Michael P., Brancale, Andrea, Williams, Pete A.

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NMNAT2 is a druggable target to drive neuronal NAD production by Tribble, James R., Jöe, Melissa, Varricchio, Carmine, Otmani, Amin, Canovai, Alessio, Habchi, Baninia, Daskalakis, Evangelia, Chaleckis, Romanas, Loreto, Andrea, Gilley, Jonathan, Wheelock, Craig E., Jóhannesson, Gauti, Wong, Raymond C. B., Coleman, Michael P., Brancale, Andrea, Williams, Pete A.

“…Maintenance of NAD pools is critical for neuronal survival. The capacity to maintain NAD pools declines in neurodegenerative disease. We identify that low…”
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Development of a CRISPRi Human Retinal Pigmented Epithelium Model for Functional Study of Age-Related Macular Degeneration Genes by Wang, Jiang-Hui, Urrutia-Cabrera, Daniel, Lees, Jarmon G, Mesa Mora, Santiago, Nguyen, Tu, Hung, Sandy S C, Hewitt, Alex W, Lim, Shiang Y, Edwards, Thomas L, Wong, Raymond C B

“…Age-related macular degeneration (AMD) is a blinding disease characterised by dysfunction of the retinal pigmented epithelium (RPE) which culminates in…”
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AAV2-mediated gene therapy for Bietti crystalline dystrophy provides functional CYP4V2 in multiple relevant cell models by Wang, Jiang-Hui, Lidgerwood, Grace E., Daniszewski, Maciej, Hu, Monica L., Roberts, Georgina E., Wong, Raymond C. B., Hung, Sandy S. C., McClements, Michelle E., Hewitt, Alex W., Pébay, Alice, Hickey, Doron G., Edwards, Thomas L.

“…Bietti crystalline dystrophy (BCD) is an inherited retinal disease (IRD) caused by mutations in the CYP4V2 gene. It is a relatively common cause of IRD in east…”
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Outcomes of adults hospitalised with severe influenza by Lee, N, Choi, K W, Chan, P K S, Hui, D S C, Lui, G C Y, Wong, B C K, Wong, R Y K, Sin, W Y, Hui, W M, Ngai, K L K, Cockram, C S, Lai, R W M, Sung, J J Y

“…The aim of this study was to investigate factors affecting clinical outcomes of adults hospitalised with severe seasonal influenza. A prospective,…”
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A Prospective Intervention Study on Higher-Dose Oseltamivir Treatment in Adults Hospitalized With Influenza A and B Infections by Lee, N., Hui, D. S. C., Zuo, Z., Ngai, K. L. K., Lui, G. C. Y., Wo, S. K., Tam, W. W. S., Chan, M. C. W., Wong, B. C. K., Wong, R. Y. K., Choi, K. W., Sin, W. W. Y., Lee, E. L. Y., Tomlinson, B., Hayden, F. G., Chan, P. K. S.

“…Background. It is unclear if higher-dose oseltamivir provides benefit beyond the standard dose in influenza patients who require hospitalization. Methods. A…”
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Electrical Stimulation Promotes Cardiac Differentiation of Human Induced Pluripotent Stem Cells by Shepherd, Robert K., Dusting, Gregory J., Lim, Shiang Y., Hung, Sandy S. C., Liang, Helena, Hewitt, Alex W., Crombie, Duncan E., Wong, Raymond C. B., Sivakumaran, Priyadharshini, Millard, Rodney, Hernández, Damián, Pébay, Alice

“…Background. Human induced pluripotent stem cells (iPSCs) are an attractive source of cardiomyocytes for cardiac repair and regeneration. In this study, we aim…”
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Traditional Chinese medicine causing hepatotoxicity in patients with chronic hepatitis B infection: a 1‐year prospective study by YUEN, M.‐F., TAM, S., FUNG, J., WONG, D. K.‐H., WONG, B. C.‐Y., LAI, C.‐L.

“…Summary Background Safety of traditional Chinese medicine in patients with chronic hepatitis B is unknown. Aim To study the clinical outcome of traditional…”
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Clinical features, biochemical parameters, and virological profiles of patients with hepatocellular carcinoma in Hong Kong by CHEUNG, T.‐K., LAI, C.‐L., WONG, B. C.‐Y., FUNG, J., YUEN, M.‐F.

“…Summary Background  Clinical features of hepatocellular carcinoma patients are changing because of screening. Aim  To examine the clinical features of…”
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Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancer by Chan, A O-O, Lam, S-K, Wong, B C-Y, Wong, W-M, Yuen, M-F, Yeung, Y-H, Hui, W-M, Rashid, A, Kwong, Y-L

“…Background:E-cadherin is an adhesion molecule involved in tumour invasion/metastasis. Silencing of E-cadherin by promoter CpG methylation has been shown in…”
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Eradication of Helicobacter pylori infection reverses E-cadherin promoter hypermethylation by Chan, A O O, Peng, J Z, Lam, S K, Lai, K C, Yuen, M F, Cheung, H K L, Kwong, Y L, Rashid, A, Chan, C K, Wong, B C-Y

“…Background: E-cadherin methylation is important in gastric carcinogenesis. Reversing hypermethylation may halt the carcinogenic process. We have previously…”
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Prevalence, clinical spectrum and health care utilization of gastro‐oesophageal reflux disease in a Chinese population: a population‐based study by Wong, W. M., Lai, K. C., Lam, K. F., Hui, W. M., Hu, W. H. C., Lam, C. L. K., Xia, H. H. X., Huang, J. Q., Chan, C. K., Lam, S. K., Wong, B. C. Y.

“…Summary Background : Population‐based data on gastro‐oesophageal reflux disease in Chinese are lacking. The prevalence, clinical spectrum and health…”
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Different physiological properties of human-residential and non-human-residential bifidobacteria in human health by Wong, C B, Sugahara, H, Odamaki, T, Xiao, J Z

“…Bifidobacteria have increasingly been shown to exert positive health benefits to humans, which are clearly reflected by their application in various…”
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Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer by Dai, Y, Wilson, G, Huang, B, Peng, M, Teng, G, Zhang, D, Zhang, R, Ebert, M P A, Chen, J, Wong, B C Y, Chan, K W, George, J, Qiao, L

“…Dysregulated Notch signaling has a critical role in the tumorigenesis. Jagged1, a Notch ligand, is overexpressed in various human cancers. Recent studies…”
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Enriched retinal ganglion cells derived from human embryonic stem cells by Gill, Katherine P., Hung, Sandy S. C., Sharov, Alexei, Lo, Camden Y., Needham, Karina, Lidgerwood, Grace E., Jackson, Stacey, Crombie, Duncan E., Nayagam, Bryony A., Cook, Anthony L., Hewitt, Alex W., Pébay, Alice, Wong, Raymond C. B.

“…Optic neuropathies are characterised by a loss of retinal ganglion cells (RGCs) that lead to vision impairment. Development of cell therapy requires a better…”
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Inhibition of Staphylococcus aureus by crude and fractionated extract from lactic acid bacteria by Wong, C-B, Khoo, B-Y, Sasidharan, S, Piyawattanametha, W, Kim, S H, Khemthongcharoen, N, Ang, M-Y, Chuah, L-O, Liong, M-T

“…Increasing levels of antibiotic resistance by Staphylococcus aureus have posed a need to search for non-antibiotic alternatives. This study aimed to assess the…”
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Role of Gap Junctions in Embryonic and Somatic Stem Cells by Wong, Raymond C. B., Pera, Martin F., Pébay, Alice

“…Stem cells provide an invaluable tool to develop cell replacement therapies for a range of serious disorders caused by cell damage or degeneration. Much…”
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Effects of ethylene glycol dimethacrylate as cross-linker in ionic liquid gel polymer electrolyte based on poly(glycidyl methacrylate) by Wong, B. C. F., Ahmad, A., Hanifah, S. A., Hassan, N. H.

“…In this study, modified poly(glycidyl methacrylate)-based films for gel electrolyte were prepared by an in situ UV photopolymerization technique. The effects…”
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