Search Results - "Wong, Brett J."

Sensory nerves and nitric oxide contribute to reflex cutaneous vasodilation in humans by Wong, Brett J

“…We tested the hypothesis that inhibition of cutaneous sensory nerves would attenuate reflex cutaneous vasodilation in response to an increase in core…”
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Transient receptor potential vanilloid type‐1 (TRPV‐1) channels contribute to cutaneous thermal hyperaemia in humans by Wong, Brett J., Fieger, Sarah M.

“…The initial, rapid increase in skin blood flow in response to direct application of heat is thought to be mediated by an axon reflex, which is dependent on…”
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Contribution of sensory nerves to cutaneous reactive hyperaemia in non‐Hispanic Black and White young adults by Turner, Casey G., Walker, Demetria C., Wong, Brett J.

“…New Findings What is the central question of this study? Does cutaneous sensory nerve‐mediated vasodilatation differ between non‐Hispanic Black and White young…”
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Reply to Letter to the Editor in response to: Microvascular endothelial function following cessation of long‐term oral contraceptive pill use by Turner, Casey G., Stanhewicz, Anna E., Nielsen, Karen E., Wong, Brett J.

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Microvascular endothelial function following cessation of long‐term oral contraceptive pill use: A case report by Turner, Casey G., Stanhewicz, Anna E., Nielsen, Karen E., Wong, Brett J.

“…New Findings What is the main observation in this case? The main observation of this case report is substantial improvement in cutaneous microvascular…”
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Berry-Derived Polyphenols in Cardiovascular Pathologies: Mechanisms of Disease and the Role of Diet and Sex by Najjar, Rami S, Turner, Casey G, Wong, Brett J, Feresin, Rafaela G

“…Cardiovascular disease (CVD) prevalence, pathogenesis, and manifestation is differentially influenced by biological sex. Berry polyphenols target several…”
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Sensory nerve-mediated and nitric oxide-dependent cutaneous vasodilation in normotensive and prehypertensive non-Hispanic blacks and whites by Wong, Brett J, Turner, Casey G, Miller, James T, Walker, Demetria C, Sebeh, Yesser, Hayat, Matthew J, Otis, Jeffrey S, Quyyumi, Arshed A

“…The purpose of this study was to investigate the effect of race and subclinical elevations in blood pressure (i.e., prehypertension) on cutaneous sensory…”
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Female Sex Hormone Effects on the Vasculature: Considering the Validity of Restricting Study Inclusion to Low-Hormone Phases by Turner, Casey G., Stanhewicz, Anna E., Wong, Brett J.

“…Many studies of vascular function limit the testing of premenopausal female participants to periods when female sex hormones, either endogenous or exogenous,…”
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Endothelial nitric oxide synthase mediates the nitric oxide component of reflex cutaneous vasodilatation during dynamic exercise in humans by McNamara, Tanner C., Keen, Jeremy T., Simmons, Grant H., Alexander, Lacy M., Wong, Brett J.

“…Key points Increases in skin blood flow and sweating also occur during exercise; however, it is not known if the mechanisms controlling these responses are the…”
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Transient receptor potential vanilloid type 1 channels contribute to reflex cutaneous vasodilation in humans by Wong, Brett J, Fieger, Sarah M

“…Mechanisms underlying the cutaneous vasodilation in response to an increase in core temperature remain unresolved. The purpose of this study was to determine a…”
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Current concepts of active vasodilation in human skin by Wong, Brett J., Hollowed, Casey G.

“…In humans, an increase in internal core temperature elicits large increases in skin blood flow and sweating. The increase in skin blood flow serves to transfer…”
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Berries and Their Polyphenols as a Potential Therapy for Coronary Microvascular Dysfunction: A Mini-Review by Najjar, Rami S, Schwartz, Arielle M, Wong, Brett J, Mehta, Puja K, Feresin, Rafaela G

“…Ischemia with no obstructive coronary artery disease (INOCA) is a common diagnosis with a higher prevalence in women compared to men. Despite the absence of…”
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Heat therapy promotes the expression of angiogenic regulators in human skeletal muscle by Kuhlenhoelter, Alisha M, Kim, Kyoungrae, Neff, Dustin, Nie, Yaohui, Blaize, A Nicole, Wong, Brett J, Kuang, Shihuan, Stout, Julianne, Song, Qifan, Gavin, Timothy P, Roseguini, Bruno T

“…Heat therapy has been shown to promote capillary growth in skeletal muscle and in the heart in several animal models, but the effects of this therapy on…”
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Tissue Derivation and Biological Sex Uniquely Mediate Endothelial Cell Protein Expression, Redox Status, and Nitric Oxide Synthesis by Najjar, Rami S, Wong, Brett J, Feresin, Rafaela G

“…Human endothelial cells are routinely utilized in cardiovascular research to provide a translational foundation for understanding how the vascular endothelium…”
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Short-term dietary nitrate supplementation augments cutaneous vasodilatation and reduces mean arterial pressure in healthy humans by Keen, Jeremy T., Levitt, Erica L., Hodges, Gary J., Wong, Brett J.

“…Nitrate supplementation in the form of beetroot juice has been shown to increase nitric oxide (NO) where nitrate can be reduced to nitrite and, subsequently,…”
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Augmented reflex cutaneous vasodilatation following short‐term dietary nitrate supplementation in humans by Levitt, Erica L., Keen, Jeremy T., Wong, Brett J.

“…New Findings What is the central question of this study? Nitrate supplementation via beetroot juice has been shown to have several benefits in healthy humans,…”
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The effect of endothelin a receptor inhibition and biological sex on cutaneous microvascular function in non‐Hispanic Black and White young adults by Turner, Casey G., Hayat, Matthew J., Otis, Jeffrey S., Quyyumi, Arshed A., Wong, Brett J.

“…The purpose of this study was to investigate whether endothelin‐A receptor (ETAR) inhibition in non‐Hispanic Black (NHB) and White (NHW) young adults depends…”
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Increased brachial artery retrograde shear rate at exercise onset is abolished during prolonged cycling: role of thermoregulatory vasodilation by SIMMONS, Grant H, PADILLA, Jaume, YOUNG, Colin N, WONG, Brett J, LANG, James A, DAVIS, Michael J, HAROLD LAUGHLIN, M, FADEL, Paul J

“…Acute leg exercise increases brachial artery retrograde shear rate (SR), while chronic exercise improves vasomotor function. These combined observations are…”
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Inhibition of superoxide and iNOS augment cutaneous nitric oxide-dependent vasodilation in non-Hispanic black young adults by Wong, Brett J, Turner, Casey G, Hayat, Matthew J, Otis, Jeffrey S, Quyyumi, Arshed A

“…We assessed the combined effect of superoxide and iNOS inhibition on microvascular function in non-Hispanic Black and non-Hispanic White participants (n = 15…”
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Counterpoint: Investigators should not control for menstrual cycle phase when performing studies of vascular control that include women by Stanhewicz, Anna E, Wong, Brett J

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