Search Results - "Wong, Ashley"

Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine by Kavanagh, Madeline E., Horning, Benjamin D., Khattri, Roli, Roy, Nilotpal, Lu, Justine P., Whitby, Landon R., Ye, Elva, Brannon, Jaclyn C., Parker, Albert, Chick, Joel M., Eissler, Christie L., Wong, Ashley J., Rodriguez, Joe L., Rodiles, Socorro, Masuda, Kim, Teijaro, John R., Simon, Gabriel M., Patricelli, Matthew P., Cravatt, Benjamin F.

“…The Janus tyrosine kinase (JAK) family of non-receptor tyrosine kinases includes four isoforms (JAK1, JAK2, JAK3, and TYK2) and is responsible for signal…”
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NAD+ Repletion Rescues Female Fertility during Reproductive Aging by Bertoldo, Michael J., Listijono, Dave R., Ho, Wing-Hong Jonathan, Riepsamen, Angelique H., Goss, Dale M., Richani, Dulama, Jin, Xing L., Mahbub, Saabah, Campbell, Jared M., Habibalahi, Abbas, Loh, Wei-Guo Nicholas, Youngson, Neil A., Maniam, Jayanthi, Wong, Ashley S.A., Selesniemi, Kaisa, Bustamante, Sonia, Li, Catherine, Zhao, Yiqing, Marinova, Maria B., Kim, Lynn-Jee, Lau, Laurin, Wu, Rachael M., Mikolaizak, A. Stefanie, Araki, Toshiyuki, Le Couteur, David G., Turner, Nigel, Morris, Margaret J., Walters, Kirsty A., Goldys, Ewa, O’Neill, Christopher, Gilchrist, Robert B., Sinclair, David A., Homer, Hayden A., Wu, Lindsay E.

“…Reproductive aging in female mammals is an irreversible process associated with declining oocyte quality, which is the rate-limiting factor to fertility. Here,…”
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Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency by Cagnone, Gael L. M., Tsai, Te-Sha, Makanji, Yogeshwar, Matthews, Pamela, Gould, Jodee, Bonkowski, Michael S., Elgass, Kirstin D., Wong, Ashley S. A., Wu, Lindsay E., McKenzie, Matthew, Sinclair, David A., John, Justin C. St

“…An increasing number of women fail to achieve pregnancy due to either failed fertilization or embryo arrest during preimplantation development. This often…”
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Selenium and Metabolic Disorders: An Emphasis on Type 2 Diabetes Risk by Ogawa-Wong, Ashley N, Berry, Marla J, Seale, Lucia A

“…Selenium (Se) is a micronutrient that maintains biological functions through the action of Se containing proteins known as selenoproteins. Due to the known…”
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An update on the pharmacodynamics, pharmacokinetics, safety and clinical efficacy of nivolumab in the treatment of solid cancers by Wong, Ashley C Y, Ma, Brigette

“…Nivolumab is a programmed cell death 1 (PD-1) inhibitor that has been approved for treatment of advanced melanoma, non-small cell lung carcinoma, renal cell…”
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Major Short-term Complications of Arterial Cannulation for Monitoring in Children by Gleich, Stephen J., Wong, Ashley V., Handlogten, Kathryn S., Thum, Daniel E., Nemergut, Michael E.

“…BACKGROUND:Perioperative arterial cannulation in children is routinely performed. Based on clinical observation of several complications related to femoral…”
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Impact of the COVID-19 pandemic on sports and exercise by Wong, Ashley Ying-Ying, Ling, Samuel Ka-Kin, Louie, Lobo Hung-Tak, Law, George Ying-Kan, So, Raymond Chi-Hung, Lee, Daniel Chi-Wo, Yau, Forrest Chung-Fai, Yung, Patrick Shu-Hang

“…COVID-19 is a droplet-transmitted potentially fatal coronavirus pandemic affecting the world in 2020. The WHO recommended social distancing and human-to-human…”
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Leadless pacemaker implantation for pediatric patients through internal jugular vein approach: A case series of under 30 kg by Siddeek, Hani, Alabsi, Sarah, Wong, Ashley, Cortez, Daniel

“…We demonstrate a case series of 8 pediatric patients, all under 30 kg, who had leadless pacemaker implants via the internal jugular vein. A retrospective…”
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SIRT2 transgenic over‐expression does not impact lifespan in mice by Wu, Lindsay E., Fiveash, Corrine E., Bentley, Nicholas L., Kang, Myung‐Jin, Govindaraju, Hemna, Barbour, Jayne A., Wilkins, Brendan P., Hancock, Sarah E., Madawala, Romanthi, Das, Abhijit, Massudi, Hassina, Li, Catherine, Kim, Lynn‐Jee, Wong, Ashley S. A., Marinova, Maria B., Sultani, Ghazal, Das, Abhirup, Youngson, Neil A., Le Couteur, David G., Sinclair, David A., Turner, Nigel

“…The NAD+‐dependent deacylase family of sirtuin enzymes have been implicated in biological ageing, late‐life health and overall lifespan, though of these…”
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Labor Analgesia in a Patient with Severe Dystrophic Calcinosis Cutis by Wong, Ashley V, Abcejo, Arnoley S, Dahl, Ashley R D, Sharpe, Emily E

“…Abstract Introduction Calcinosis cutis is a condition characterized by pathologic calcium deposition into superficial dermal skin layers. It is often…”
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Prospects for the computational humanization of antibodies and nanobodies by Gordon, Gemma L, Raybould, Matthew I J, Wong, Ashley, Deane, Charlotte M

“…To be viable therapeutics, antibodies must be tolerated by the human immune system. Rational approaches to reduce the risk of unwanted immunogenicity involve…”
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The timing of initiation of pharmacotherapy for women with gestational diabetes mellitus by Harrison, Rachel K, Cruz, Meredith, Wong, Ashley, Davitt, Caroline, Palatnik, Anna

“…The decision to initiate pharmacotherapy is integral in the care for pregnant women with gestational diabetes mellitus (GDM). We sought to compare pregnancy…”
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LETTER TO THE EDITOR Re: First live birth after fertility preservation using vitrification of oocytes in a woman with mosaic Turner syndrome by Bamba, Vaneeta, Levitsky, Lynne L., Wong, Ashley W., Rivera-Cruz, Greysha, Scurlock, Cindy, Lin, Angela E.

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An additional patient with SMAD4‐Juvenile Polyposis‐Hereditary hemorrhagic telangiectasia and connective tissue abnormalities: SMAD4 loss‐of‐function and gain‐of‐function pathogenic variants result in contrasting phenotypes by Gheewalla, Gregory M., Luther, Jay, Das, Saumya, Kreher, Jeffrey B., Scimone, Eleanor R., Wong, Ashley W., Lindsay, Mark E., Lin, Angela E.

“…Loss‐of‐function pathogenic variants in somatic and germline cells in SMAD4 may cause cancer and juvenile polyposis‐Hereditary Hemorrhagic Telangiectasia…”
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Optimizing pediatric periprocedural pain management part II-Adjunct therapies to support the use of infiltrative anesthetics by Henkel, Emily D, Haller, Courtney N, Diaz, Lucia Z, Ricles, Victoria, Wong Grossman, Ashley V, Nemergut, Michael E, Krakowski, Andrew C

“…Pediatric procedure-related pain management is often incompletely understood, inadequately addressed, and critical in influencing a child's lifelong…”
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SEXUAL DIMORPHISM IN SELENIUM METABOLISM AND SELENOPROTEINS by Seale, Lucia A., Ogawa-Wong, Ashley N., Berry, Marla J.

“…Sexual dimorphism, the condition in which males and females in a species differ beyond the morphology of sex organs, delineates critical aspects of the biology…”
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Selenoproteins in Nervous System Development and Function by Pitts, Matthew W., Byrns, China N., Ogawa-Wong, Ashley N., Kremer, Penny, Berry, Marla J.

“…Selenoproteins are a distinct class of proteins that are characterized by the co-translational incorporation of selenium (Se) in the form of the 21st amino…”
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Nucleation and Crystal Growth of Nanocrystalline Anatase and Rutile Phase TiO2 from a Water-Soluble Precursor by Kinsinger, Nichola M, Wong, Ashley, Li, Dongsheng, Villalobos, Fabian, Kisailus, David

“…Titanium dioxide (TiO2) has been widely used as an advanced semiconductor and as a white pigment for many years. In recent years, TiO2 has gained much more…”
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Sexual Dimorphism in the Selenocysteine Lyase Knockout Mouse by Ogawa-Wong, Ashley N, Hashimoto, Ann C, Ha, Herena, Pitts, Matthew W, Seale, Lucia A, Berry, Marla J

“…Selenium (Se) is an essential micronutrient known for its antioxidant properties and health benefits, attributed to its presence in selenoproteins as the amino…”
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Comparison of the in vivo kinematics between robotic‐assisted Bi‐cruciate retaining and Bi‐cruciate stabilised total knee arthroplasty by Wong, Ashley Ying‐Ying, Ong, Michael Tim‐Yun, Choi, Tsz Lung, Lam, Gloria Yan‐Ting, He, Xin, Yu, Mingqian, Choi, Ben Chi‐Yin, Fong, Daniel T. P., Yung, Patrick Shu‐Hang

“…Background Up to 20% of patients remain unsatisfied after total knee arthroplasty (TKA), prompting the development of new implants. Bi‐Cruciate Retaining (BCR)…”
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