Search Results - "Wong, Annette T.Y."

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    Nonalcoholic Fatty Liver Disease as the Transducer of Hepatic Oversecretion of Very-Low-Density Lipoprotein–Apolipoprotein B-100 in Obesity by Chan, Dick C, Watts, Gerald F, Gan, SengKhee, Wong, Annette T.Y, Ooi, Esther M.M, Barrett, P Hugh R

    “…OBJECTIVE—To examine the association between liver fat content and very low-density lipoprotein (VLDL)–apolipoprotein (apo) B-100 kinetics and the…”
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    Apolipoprotein B-48 as a determinant of endothelial function in obese subjects with type 2 diabetes mellitus: Effect of fenofibrate treatment by Chan, Dick C, Wong, Annette T.Y, Yamashita, S, Watts, Gerald F

    Published in Atherosclerosis (01-04-2012)
    “…Highlights ► Elevated triglyceride-rich lipoproteins may contribute to endothelial dysfunction. ► We examine the effect of fenofibrate on triglyceride-rich…”
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    Regression of Peritubular Capillaries Coincides with Angiogenesis and Renal Cyst Growth in Experimental Polycystic Kidney Disease by O'Brien, Kristal, Saravanabavan, Sayanthooran, Zhang, Jennifer Q J, Wong, Annette T Y, Munt, Alexandra, Burgess, Jane S, Rangan, Gopala K

    “…The natural history of the renal microvasculature changes in PKD is not known. The aim of this study was to test the hypothesis that angiogenesis is coupled…”
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    Apolipoprotein A-II and adiponectin as determinants of very low-density lipoprotein apolipoprotein B-100 metabolism in nonobese men by Chan, Dick C, Watts, Gerald F, Ooi, Esther M.M, Chan, Doris T, Wong, Annette T.Y, Barrett, P. Hugh R

    Published in Metabolism, clinical and experimental (01-10-2011)
    “…Abstract Data from cellular systems and transgenic animal models suggest a role of apolipoprotein (apo) A-II in the regulation of very low-density lipoprotein…”
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    Up-Regulation of DNA Damage Response Signaling in Autosomal Dominant Polycystic Kidney Disease by Zhang, Jennifer Q.J., Saravanabavan, Sayanthooran, Chandra, Ashley N., Munt, Alexandra, Wong, Annette T.Y., Harris, Peter C., Harris, David C.H., McKenzie, Paul, Wang, Yiping, Rangan, Gopala K.

    Published in The American journal of pathology (01-05-2021)
    “…DNA damage and alterations in DNA damage response (DDR) signaling could be one of the molecular mechanisms mediating focal kidney cyst formation in autosomal…”
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    Increased water intake reduces long-term renal and cardiovascular disease progression in experimental polycystic kidney disease by Sagar, Priyanka S, Zhang, Jennifer, Luciuk, Magda, Mannix, Carly, Wong, Annette T Y, Rangan, Gopala K

    Published in PloS one (02-01-2019)
    “…Polycystic kidney disease (PKD) is the most common inherited cause of kidney failure and currently has limited treatment options. Increasing water intake…”
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    Role of cyclin-dependent kinase 2 in the progression of mouse juvenile cystic kidney disease by Zhang, Jennifer Qin Jing, Burgess, Jane, Stepanova, Daria, Saravanabavan, Sayanthooran, Wong, Annette T.Y., Kaldis, Philipp, Rangan, Gopala K.

    Published in Laboratory investigation (01-05-2020)
    “…A hallmark of polycystic kidney diseases (PKDs) is aberrant proliferation, which leads to the formation and growth of renal cysts. Proliferation is mediated by…”
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    Long-term dietary nitrate supplementation does not reduce renal cyst growth in experimental autosomal dominant polycystic kidney disease by Zhang, Jennifer Q J, Saravanabavan, Sayanthooran, Cheng, Kai Man, Raghubanshi, Aarya, Chandra, Ashley N, Munt, Alexandra, Rayner, Benjamin, Zhang, Yunjia, Chau, Katrina, Wong, Annette T Y, Rangan, Gopala K

    Published in PloS one (22-04-2021)
    “…Augmentation of endogenous nitric oxide (NO) synthesis, either by the classical L-arginine-NO synthase pathway, or the recently discovered entero-salivary…”
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    Inter-relationships between proprotein convertase subtilisin/kexin type 9, apolipoprotein C-III and plasma apolipoprotein B-48 transport in obese subjects: a stable isotope study in the postprandial state by Chan, Dick C, Wong, Annette T Y, Pang, Jing, Barrett, P Hugh R, Watts, Gerald F

    Published in Clinical science (1979) (01-03-2015)
    “…Postprandial lipaemia, due to elevated plasma apolipoprotein (apo) B-48 concentrations, contributes to increased cardiovascular (CV) risk in obesity…”
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    Plasma Apolipoprotein B-48 Transport in Obese Men: A New Tracer Kinetic Study in the Postprandial State by Wong, Annette T. Y, Chan, Dick C, Pang, Jing, Watts, Gerald F, Barrett, P. Hugh R

    “…Context: The mechanisms responsible for impaired chylomicron metabolism have not been adequately investigated in obese subjects. Objective: We aimed to compare…”
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    The role of DNA damage as a therapeutic target in autosomal dominant polycystic kidney disease by Zhang, Jennifer Q J, Saravanabavan, Sayanthooran, Munt, Alexandra, Wong, Annette T Y, Harris, David C, Harris, Peter C, Wang, Yiping, Rangan, Gopala K

    Published in Expert reviews in molecular medicine (26-11-2019)
    “…Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic kidney disease and is caused by heterozygous germ-line mutations in either…”
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    Effect of ω-3 Fatty Acid Ethyl Esters on Apolipoprotein B-48 Kinetics in Obese Subjects on a Weight-Loss Diet: A New Tracer Kinetic Study in the Postprandial State by Wong, Annette T. Y, Chan, Dick C, Barrett, P. Hugh R, Adams, Leon A, Watts, Gerald F

    “…Context: Dysregulated chylomicron metabolism may account for hypertriglyceridemia and increased risk of cardiovascular disease in obese subjects…”
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    Effect of Early and Delayed Commencement of Paricalcitol in Combination with Enalapril on the Progression of Experimental Polycystic Kidney Disease by Sagar, Priyanka S., Saravanabavan, Sayanthooran, Munt, Alexandra, Wong, Annette T. Y., Rangan, Gopala K.

    “…Vitamin D secosteroids are intranuclear regulators of cellular growth and suppress the renin-angiotensin system. The aim of this study was to test the…”
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    Supplementation with n3 fatty acid ethyl esters increases large and small artery elasticity in obese adults on a weight loss diet by Wong, Annette T Y, Chan, Dick C, Barrett, P Hugh R, Adams, Leon A, Watts, Gerald F

    Published in The Journal of nutrition (01-04-2013)
    “…Increased arterial stiffness is associated with enhanced risk of cardiovascular disease in obese individuals. Whether n3 fatty acid ethyl ester (FAEE)…”
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    Omega-3 fatty acid ethyl ester supplementation decreases very-low-density lipoprotein triacylglycerol secretion in obese men by Wong, Annette T Y, Chan, Dick C, Ooi, Esther M M, Ng, Theodore W K, Watts, Gerald F, Barrett, P Hugh R

    Published in Clinical science (1979) (01-07-2013)
    “…Dysregulated VLDL-TAG (very-low-density lipoprotein triacylglycerol) metabolism in obesity may account for hypertriacylglycerolaemia and increased…”
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