Search Results - "Wong, Annette T.Y."
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Nonalcoholic Fatty Liver Disease as the Transducer of Hepatic Oversecretion of Very-Low-Density Lipoprotein–Apolipoprotein B-100 in Obesity
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2010)“…OBJECTIVE—To examine the association between liver fat content and very low-density lipoprotein (VLDL)–apolipoprotein (apo) B-100 kinetics and the…”
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Process evaluation of TXT2BFiT: a multi-component mHealth randomised controlled trial to prevent weight gain in young adults
Published in The international journal of behavioral nutrition and physical activity (19-01-2016)“…BACKGROUND: TXT2BFiT was one of the first few innovative mHealth programs designed for young adults (18–35 years) with demonstrated efficacy in weight…”
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Apolipoprotein B-48 as a determinant of endothelial function in obese subjects with type 2 diabetes mellitus: Effect of fenofibrate treatment
Published in Atherosclerosis (01-04-2012)“…Highlights ► Elevated triglyceride-rich lipoproteins may contribute to endothelial dysfunction. ► We examine the effect of fenofibrate on triglyceride-rich…”
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Regression of Peritubular Capillaries Coincides with Angiogenesis and Renal Cyst Growth in Experimental Polycystic Kidney Disease
Published in International journal of nephrology and renovascular disease (01-01-2020)“…The natural history of the renal microvasculature changes in PKD is not known. The aim of this study was to test the hypothesis that angiogenesis is coupled…”
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Apolipoprotein A-II and adiponectin as determinants of very low-density lipoprotein apolipoprotein B-100 metabolism in nonobese men
Published in Metabolism, clinical and experimental (01-10-2011)“…Abstract Data from cellular systems and transgenic animal models suggest a role of apolipoprotein (apo) A-II in the regulation of very low-density lipoprotein…”
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Up-Regulation of DNA Damage Response Signaling in Autosomal Dominant Polycystic Kidney Disease
Published in The American journal of pathology (01-05-2021)“…DNA damage and alterations in DNA damage response (DDR) signaling could be one of the molecular mechanisms mediating focal kidney cyst formation in autosomal…”
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Effectiveness of a mHealth Lifestyle Program With Telephone Support (TXT2BFiT) to Prevent Unhealthy Weight Gain in Young Adults: Randomized Controlled Trial
Published in JMIR mHealth and uHealth (15-06-2015)“…Weight gained in young adulthood often persists throughout later life with associated chronic disease risk. Despite this, current population prevention…”
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Increased water intake reduces long-term renal and cardiovascular disease progression in experimental polycystic kidney disease
Published in PloS one (02-01-2019)“…Polycystic kidney disease (PKD) is the most common inherited cause of kidney failure and currently has limited treatment options. Increasing water intake…”
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Clinical characteristics and outcomes of hyponatraemia associated with oral water intake in adults: a systematic review
Published in BMJ open (09-12-2021)“…IntroductionExcessive water intake is rarely associated with life-threatening hyponatraemia. The aim of this study was to determine the clinical…”
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Role of cyclin-dependent kinase 2 in the progression of mouse juvenile cystic kidney disease
Published in Laboratory investigation (01-05-2020)“…A hallmark of polycystic kidney diseases (PKDs) is aberrant proliferation, which leads to the formation and growth of renal cysts. Proliferation is mediated by…”
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Long-term dietary nitrate supplementation does not reduce renal cyst growth in experimental autosomal dominant polycystic kidney disease
Published in PloS one (22-04-2021)“…Augmentation of endogenous nitric oxide (NO) synthesis, either by the classical L-arginine-NO synthase pathway, or the recently discovered entero-salivary…”
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Inter-relationships between proprotein convertase subtilisin/kexin type 9, apolipoprotein C-III and plasma apolipoprotein B-48 transport in obese subjects: a stable isotope study in the postprandial state
Published in Clinical science (1979) (01-03-2015)“…Postprandial lipaemia, due to elevated plasma apolipoprotein (apo) B-48 concentrations, contributes to increased cardiovascular (CV) risk in obesity…”
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Plasma Apolipoprotein B-48 Transport in Obese Men: A New Tracer Kinetic Study in the Postprandial State
Published in The journal of clinical endocrinology and metabolism (01-01-2014)“…Context: The mechanisms responsible for impaired chylomicron metabolism have not been adequately investigated in obese subjects. Objective: We aimed to compare…”
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Randomised controlled trial to determine the efficacy and safety of prescribed water intake to prevent kidney failure due to autosomal dominant polycystic kidney disease (PREVENT-ADPKD)
Published in BMJ open (01-01-2018)“…IntroductionMaintaining fluid intake sufficient to reduce arginine vasopressin (AVP) secretion has been hypothesised to slow kidney cyst growth in autosomal…”
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The role of DNA damage as a therapeutic target in autosomal dominant polycystic kidney disease
Published in Expert reviews in molecular medicine (26-11-2019)“…Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic kidney disease and is caused by heterozygous germ-line mutations in either…”
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Effect of ω-3 Fatty Acid Ethyl Esters on Apolipoprotein B-48 Kinetics in Obese Subjects on a Weight-Loss Diet: A New Tracer Kinetic Study in the Postprandial State
Published in The journal of clinical endocrinology and metabolism (01-08-2014)“…Context: Dysregulated chylomicron metabolism may account for hypertriglyceridemia and increased risk of cardiovascular disease in obese subjects…”
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Effect of Early and Delayed Commencement of Paricalcitol in Combination with Enalapril on the Progression of Experimental Polycystic Kidney Disease
Published in Journal of cardiovascular development and disease (29-10-2021)“…Vitamin D secosteroids are intranuclear regulators of cellular growth and suppress the renin-angiotensin system. The aim of this study was to test the…”
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Supplementation with n3 fatty acid ethyl esters increases large and small artery elasticity in obese adults on a weight loss diet
Published in The Journal of nutrition (01-04-2013)“…Increased arterial stiffness is associated with enhanced risk of cardiovascular disease in obese individuals. Whether n3 fatty acid ethyl ester (FAEE)…”
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Assessment of Dietary Sodium Intake Using the Scored Salt Questionnaire in Autosomal Dominant Polycystic Kidney Disease
Published in Nutrients (02-11-2020)“…The excess intake of dietary sodium is a key modifiable factor for reducing disease progression in autosomal dominant polycystic kidney disease (ADPKD). The…”
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Omega-3 fatty acid ethyl ester supplementation decreases very-low-density lipoprotein triacylglycerol secretion in obese men
Published in Clinical science (1979) (01-07-2013)“…Dysregulated VLDL-TAG (very-low-density lipoprotein triacylglycerol) metabolism in obesity may account for hypertriacylglycerolaemia and increased…”
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