Search Results - "Wong, Annette T Y"

Increased water intake reduces long-term renal and cardiovascular disease progression in experimental polycystic kidney disease by Sagar, Priyanka S, Zhang, Jennifer, Luciuk, Magda, Mannix, Carly, Wong, Annette T Y, Rangan, Gopala K

“…Polycystic kidney disease (PKD) is the most common inherited cause of kidney failure and currently has limited treatment options. Increasing water intake…”
Get full text

Long-term dietary nitrate supplementation does not reduce renal cyst growth in experimental autosomal dominant polycystic kidney disease by Zhang, Jennifer Q J, Saravanabavan, Sayanthooran, Cheng, Kai Man, Raghubanshi, Aarya, Chandra, Ashley N, Munt, Alexandra, Rayner, Benjamin, Zhang, Yunjia, Chau, Katrina, Wong, Annette T Y, Rangan, Gopala K

“…Augmentation of endogenous nitric oxide (NO) synthesis, either by the classical L-arginine-NO synthase pathway, or the recently discovered entero-salivary…”
Get full text

Role of cyclin-dependent kinase 2 in the progression of mouse juvenile cystic kidney disease by Zhang, Jennifer Qin Jing, Burgess, Jane, Stepanova, Daria, Saravanabavan, Sayanthooran, Wong, Annette T.Y., Kaldis, Philipp, Rangan, Gopala K.

“…A hallmark of polycystic kidney diseases (PKDs) is aberrant proliferation, which leads to the formation and growth of renal cysts. Proliferation is mediated by…”
Get full text

Inter-relationships between proprotein convertase subtilisin/kexin type 9, apolipoprotein C-III and plasma apolipoprotein B-48 transport in obese subjects: a stable isotope study in the postprandial state by Chan, Dick C, Wong, Annette T Y, Pang, Jing, Barrett, P Hugh R, Watts, Gerald F

“…Postprandial lipaemia, due to elevated plasma apolipoprotein (apo) B-48 concentrations, contributes to increased cardiovascular (CV) risk in obesity…”
Get more information

Plasma Apolipoprotein B-48 Transport in Obese Men: A New Tracer Kinetic Study in the Postprandial State by Wong, Annette T. Y, Chan, Dick C, Pang, Jing, Watts, Gerald F, Barrett, P. Hugh R

“…Context: The mechanisms responsible for impaired chylomicron metabolism have not been adequately investigated in obese subjects. Objective: We aimed to compare…”
Get full text

Process evaluation of TXT2BFiT: a multi-component mHealth randomised controlled trial to prevent weight gain in young adults by Partridge, Stephanie R, Allman-Farinelli, Margaret, McGeechan, Kevin, Balestracci, Kate, Wong, Annette T.Y, Hebden, Lana, Harris, Mark F, Bauman, Adrian, Phongsavan, Philayrath

“…BACKGROUND: TXT2BFiT was one of the first few innovative mHealth programs designed for young adults (18–35 years) with demonstrated efficacy in weight…”
Get full text

Effect of ω-3 Fatty Acid Ethyl Esters on Apolipoprotein B-48 Kinetics in Obese Subjects on a Weight-Loss Diet: A New Tracer Kinetic Study in the Postprandial State by Wong, Annette T. Y, Chan, Dick C, Barrett, P. Hugh R, Adams, Leon A, Watts, Gerald F

“…Context: Dysregulated chylomicron metabolism may account for hypertriglyceridemia and increased risk of cardiovascular disease in obese subjects…”
Get full text

Effect of Early and Delayed Commencement of Paricalcitol in Combination with Enalapril on the Progression of Experimental Polycystic Kidney Disease by Sagar, Priyanka S., Saravanabavan, Sayanthooran, Munt, Alexandra, Wong, Annette T. Y., Rangan, Gopala K.

“…Vitamin D secosteroids are intranuclear regulators of cellular growth and suppress the renin-angiotensin system. The aim of this study was to test the…”
Get full text

Supplementation with n3 fatty acid ethyl esters increases large and small artery elasticity in obese adults on a weight loss diet by Wong, Annette T Y, Chan, Dick C, Barrett, P Hugh R, Adams, Leon A, Watts, Gerald F

“…Increased arterial stiffness is associated with enhanced risk of cardiovascular disease in obese individuals. Whether n3 fatty acid ethyl ester (FAEE)…”
Get more information

Apolipoprotein B-48 as a determinant of endothelial function in obese subjects with type 2 diabetes mellitus: Effect of fenofibrate treatment by Chan, Dick C, Wong, Annette T.Y, Yamashita, S, Watts, Gerald F

“…Highlights ► Elevated triglyceride-rich lipoproteins may contribute to endothelial dysfunction. ► We examine the effect of fenofibrate on triglyceride-rich…”
Get full text

Assessment of Dietary Sodium Intake Using the Scored Salt Questionnaire in Autosomal Dominant Polycystic Kidney Disease by Wong, Annette T Y, Munt, Alexandra, Allman-Farinelli, Margaret, Badve, Sunil V, Boudville, Neil, Coolican, Helen, Chandra, Ashley N, Coulshed, Susan, Fernando, Mangalee, Grantham, Jared, Haloob, Imad, Harris, David C H, Hawley, Carmel M, Holt, Jane, Johnson, David W, Kumar, Karthik, Lee, Vincent W, Lonergan, Maureen, Mai, Jun, Rangan, Anna, Roger, Simon D, Saravanabavan, Sayanthooran, Sud, Kamal, Torres, Vicente E, Vilayur, Eswari, Zhang, Jennifer Q J, Rangan, Gopala K

“…The excess intake of dietary sodium is a key modifiable factor for reducing disease progression in autosomal dominant polycystic kidney disease (ADPKD). The…”
Get full text

Omega-3 fatty acid ethyl ester supplementation decreases very-low-density lipoprotein triacylglycerol secretion in obese men by Wong, Annette T Y, Chan, Dick C, Ooi, Esther M M, Ng, Theodore W K, Watts, Gerald F, Barrett, P Hugh R

“…Dysregulated VLDL-TAG (very-low-density lipoprotein triacylglycerol) metabolism in obesity may account for hypertriacylglycerolaemia and increased…”
Get more information

Effect of laparoscopic sleeve gastrectomy on elevated C-reactive protein and atherogenic dyslipidemia in morbidly obese patients by Wong, Annette T.Y., Chan, Dick C., Armstrong, Jon, Watts, Gerald F.

“…To examine the effect of weight loss by laparoscopic sleeve gastrectomy (LSG) on plasma hs-CRP and lipid profiles in morbidly obese patients. A mean follow-up…”
Get full text

Regression of Peritubular Capillaries Coincides with Angiogenesis and Renal Cyst Growth in Experimental Polycystic Kidney Disease by O'Brien, Kristal, Saravanabavan, Sayanthooran, Zhang, Jennifer Q J, Wong, Annette T Y, Munt, Alexandra, Burgess, Jane S, Rangan, Gopala K

“…The natural history of the renal microvasculature changes in PKD is not known. The aim of this study was to test the hypothesis that angiogenesis is coupled…”
Get full text

Apolipoprotein A-II and adiponectin as determinants of very low-density lipoprotein apolipoprotein B-100 metabolism in nonobese men by Chan, Dick C, Watts, Gerald F, Ooi, Esther M.M, Chan, Doris T, Wong, Annette T.Y, Barrett, P. Hugh R

“…Abstract Data from cellular systems and transgenic animal models suggest a role of apolipoprotein (apo) A-II in the regulation of very low-density lipoprotein…”
Get full text

Up-Regulation of DNA Damage Response Signaling in Autosomal Dominant Polycystic Kidney Disease by Zhang, Jennifer Q.J., Saravanabavan, Sayanthooran, Chandra, Ashley N., Munt, Alexandra, Wong, Annette T.Y., Harris, Peter C., Harris, David C.H., McKenzie, Paul, Wang, Yiping, Rangan, Gopala K.

“…DNA damage and alterations in DNA damage response (DDR) signaling could be one of the molecular mechanisms mediating focal kidney cyst formation in autosomal…”
Get full text

Randomised controlled trial to determine the efficacy and safety of prescribed water intake to prevent kidney failure due to autosomal dominant polycystic kidney disease (PREVENT-ADPKD) by Wong, Annette T Y, Mannix, Carly, Grantham, Jared J, Allman-Farinelli, Margaret, Badve, Sunil V, Boudville, Neil, Byth, Karen, Chan, Jessie, Coulshed, Susan, Edwards, Marie E, Erickson, Bradley J, Fernando, Mangalee, Foster, Sheryl, Haloob, Imad, Harris, David C H, Hawley, Carmel M, Hill, Julie, Howard, Kirsten, Howell, Martin, Jiang, Simon H, Johnson, David W, Kline, Timothy L, Kumar, Karthik, Lee, Vincent W, Lonergan, Maureen, Mai, Jun, McCloud, Philip, Peduto, Anthony, Rangan, Anna, Roger, Simon D, Sud, Kamal, Torres, Vincent, Vliayuri, Eswari, Rangan, Gopala K

“…IntroductionMaintaining fluid intake sufficient to reduce arginine vasopressin (AVP) secretion has been hypothesised to slow kidney cyst growth in autosomal…”
Get full text

The role of DNA damage as a therapeutic target in autosomal dominant polycystic kidney disease by Zhang, Jennifer Q J, Saravanabavan, Sayanthooran, Munt, Alexandra, Wong, Annette T Y, Harris, David C, Harris, Peter C, Wang, Yiping, Rangan, Gopala K

“…Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic kidney disease and is caused by heterozygous germ-line mutations in either…”
Get more information

Clinical characteristics and outcomes of hyponatraemia associated with oral water intake in adults: a systematic review by Rangan, Gopala K, Dorani, Nilofar, Zhang, Miranda M, Abu-Zarour, Lara, Lau, Ho Ching, Munt, Alexandra, Chandra, Ashley N, Saravanabavan, Sayanthooran, Rangan, Anna, Zhang, Jennifer Q J, Howell, Martin, Wong, Annette TY

“…IntroductionExcessive water intake is rarely associated with life-threatening hyponatraemia. The aim of this study was to determine the clinical…”
Get full text

Nonalcoholic Fatty Liver Disease as the Transducer of Hepatic Oversecretion of Very-Low-Density Lipoprotein–Apolipoprotein B-100 in Obesity by Chan, Dick C, Watts, Gerald F, Gan, SengKhee, Wong, Annette T.Y, Ooi, Esther M.M, Barrett, P Hugh R

“…OBJECTIVE—To examine the association between liver fat content and very low-density lipoprotein (VLDL)–apolipoprotein (apo) B-100 kinetics and the…”
Get full text