Search Results - "Won, Kyu Chang"

Ferroptosis Signaling in Pancreatic β-Cells: Novel Insights & Therapeutic Targeting by Elumalai, Suma, Karunakaran, Udayakumar, Moon, Jun-Sung, Won, Kyu-Chang

“…Metabolic stress impairs pancreatic β-cell survival and function in diabetes. Although the pathophysiology of metabolic stress is complex, aberrant tissue…”
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CD36 Signal Transduction in Metabolic Diseases: Novel Insights and Therapeutic Targeting by Karunakaran, Udayakumar, Elumalai, Suma, Moon, Jun-Sung, Won, Kyu-Chang

“…The cluster of differentiation 36 (CD36) is a scavenger receptor present on various types of cells and has multiple biological functions that may be important…”
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NADPH Oxidase (NOX) Targeting in Diabetes: A Special Emphasis on Pancreatic β-Cell Dysfunction by Elumalai, Suma, Karunakaran, Udayakumar, Moon, Jun-Sung, Won, Kyu-Chang

“…In type 2 diabetes, metabolic stress has a negative impact on pancreatic β-cell function and survival (T2D). Although the pathogenesis of metabolic stress is…”
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Low alanine aminotransferase levels predict low muscle strength in older patients with diabetes: A nationwide cross‐sectional study in Korea by Chung, Seung Min, Moon, Jun Sung, Yoon, Ji Sung, Won, Kyu Chang, Lee, Hyoung Woo

“…Aim Low alanine aminotransferase (ALT) level is associated with frailty in the older adult population. We investigated the usefulness of ALT in predicting low…”
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Endoplasmic Reticulum Stress-Induced Activation of Activating Transcription Factor 6 Decreases Insulin Gene Expression via Up-Regulation of Orphan Nuclear Receptor Small Heterodimer Partner by Seo, Hye-Young, Kim, Yong Deuk, Lee, Kyeong-Min, Min, Ae-Kyung, Kim, Mi-Kyung, Kim, Hye-Soon, Won, Kyu-Chang, Park, Joong-Yeol, Lee, Ki-Up, Choi, Hueng-Sik, Park, Keun-Gyu, Lee, In-Kyu

“…The highly developed endoplasmic reticulum (ER) structure of pancreatic β-cells is a key factor in β-cell function. Here we examined whether ER stress-induced…”
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Evaluation and Management of Patients with Diabetes and Heart Failure: A Korean Diabetes Association and Korean Society of Heart Failure Consensus Statement by Lee, Kyu-Sun, Noh, Junghyun, Park, Seong-Mi, Choi, Kyung Mook, Kang, Seok-Min, Won, Kyu-Chang, Cho, Hyun-Jai, Moon, Min Kyong

“…Diabetes mellitus is a major risk factor for the development of heart failure. Furthermore, the prognosis of heart failure is worse in patients with diabetes…”
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Deficiency of Clusterin Exacerbates High-Fat Diet-Induced Insulin Resistance in Male Mice by Kwon, Min Jung, Ju, Tae-jin, Heo, Jung-Yoon, Kim, Yong-Woon, Kim, Jong-Yeon, Won, Kyu-Chang, Kim, Jae-Ryong, Bae, Young Kyung, Park, In-Sun, Min, Bon-Hong, Lee, In-Kyu, Park, So-Young

“…The present study examined the role of clusterin in insulin resistance in high fat-fed wild-type and clusterin knockout (KO) mice. The plasma levels of glucose…”
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Evaluation and Management of Patients With Diabetes and Heart Failure: A Korean Diabetes Association and Korean Society of Heart Failure Consensus Statement by Lee, Kyu-Sun, Noh, Junghyun, Park, Seong-Mi, Choi, Kyung Mook, Kang, Seok-Min, Won, Kyu-Chang, Cho, Hyun-Jai, Moon, Min Kyong

“…Diabetes mellitus is a major risk factor for the development of heart failure. Furthermore, the prognosis of heart failure is worse in patients with diabetes…”
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Clinical Impact of Dysglycemia in Patients with an Acute Myocardial Infarction by Chung, Jae-Wook, Park, Yeong-Seon, Seo, Jeong-Eon, Son, Yeseul, Oh, Cheol-Woo, Lee, Chan-Hee, Nam, Jong-Ho, Lee, Jung-Hee, Son, Jang-Won, Kim, Ung, Park, Jong-Seon, Won, Kyu-Chang, Shin, Dong-Gu

“…This study aimed to determine the impact of dysglycemia on myocardial injury and cardiac dysfunction in acute myocardial infarctions (AMIs). From 2005 to 2016,…”
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Association between diabetes-related factors and clinical periodontal parameters in type-2 diabetes mellitus by Kim, Eun-Kyong, Lee, Sang Gyu, Choi, Youn-Hee, Won, Kyu-Chang, Moon, Jun Sung, Merchant, Anwar T, Lee, Hee-Kyung

“…Evidence consistently shows that diabetes is a risk factor for increased prevalence of gingivitis and periodontitis. But there is a controversy about the…”
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Changes in the Quality of Life in Patients with Type 2 Diabetes Mellitus According to Physician and Patient Behaviors by Kim, Young Joo, Jeong, In Kyung, Kim, Sin Gon, Cho, Dong Hyeok, Kim, Chong Hwa, Kim, Chul Sik, Lee, Won Young, Won, Kyu Chang, Cha, Jin Hye, Lee, Juneyoung, Kim, Doo Man

“…Diabetes mellitus (DM) is the most common chronic metabolic disorder with an increasing prevalence worldwide. According to a previous study, physicians'…”
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Hemorheologic Alterations in Patients with Type 2 Diabetes Mellitus Presented with an Acute Myocardial Infarction by Park, Kyu Hwan, Kim, Ung, Choi, Kang Un, Nam, Jong Ho, Lee, Jung Hee, Lee, Chan Hee, Son, Jang Won, Park, Jong Seon, Shin, Dong Gu, Won, Kyu Chang, Moon, Jun Sung, Kim, Yu Kyung, Suh, Jang Soo

“…Hemorheologic indices are known to be related to vascular complications in variable clinical settings. However, little is known about the associations between…”
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Impact of carotid atherosclerosis detection on physician and patient behavior in the management of type 2 diabetes mellitus: a prospective, observational, multicenter study by Jeong, In-Kyung, Kim, Sin-Gon, Cho, Dong Hyeok, Kim, Chong Hwa, Kim, Chul Sik, Lee, Won-Young, Won, Kyu-Chang, Kim, Doo-Man

“…This study compared carotid ultrasound (CUS) and traditional risk calculations in determining cardiovascular disease (CVD) risk in patients with type 2…”
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CD36 dependent redoxosomes promotes ceramide-mediated pancreatic β-cell failure via p66Shc activation by Karunakaran, Udayakumar, Elumalai, Suma, Moon, Jun Sung, Won, Kyu Chang

“…Altered metabolism is implicated in the pathogenesis of beta-cell failure in type 2 diabetes (T2D). Plasma and tissue levels of ceramide species play positive…”
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Diabetes Fact Sheet in Korea 2021 by Bae, Jae Hyun, Han, Kyung-Do, Ko, Seung-Hyun, Yang, Ye Seul, Choi, Jong Han, Choi, Kyung Mook, Kwon, Hyuk-Sang, Won, Kyu Chang

“…This study aimed to investigate the prevalence and management of diabetes mellitus, risk-factor control, and comorbidities among Korean adults. We conducted a…”
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Corrigendum: Hemorheologic Alterations in Patients with Type 2 Diabetes Mellitus Presented with an Acute Myocardial Infarction by Park, Kyu Hwan, Kim, Ung, Choi, Kang Un, Nam, Jong Ho, Lee, Jung Hee, Lee, Chan Hee, Son, Jang Won, Park, Jong Seon, Shin, Dong Gu, Won, Kyu Chang, Moon, Jun Sung, Kim, Yu Kyung, Suh, Jang Soo

“…This corrects the article on p. 155 in vol. 42, PMID: 29676545…”
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Lack of Inducible Nitric Oxide Synthase Prevents Lipid-Induced Skeletal Muscle Insulin Resistance Without Attenuating Cytokine Level by Cha, Hye-Na, Song, Seung Eun, Kim, Yong-Woon, Kim, Jong-Yeon, Won, Kyu-Chang, Park, So-Young

“…We examined whether deletion of inducible nitric oxide synthase (iNOS) could prevent lipid infusion-induced insulin resistance in iNOS-knockout and wild-type…”
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COMP-angiopoietin-1 enhances skeletal muscle blood flow and insulin sensitivity in mice by Sung, Hoon-Ki, Sung, H K, Kim, Yong-Woon, Choi, Soo Jeong, Kim, Jong-Yeon, Jeune, Kyung Hee, Won, Kyu-Chang, Kim, Jason K, Koh, Gou Young, Koh, Gyu Young, Park, So-Young

“…To test whether chronic enhanced blood flow alters insulin-stimulated glucose uptake, we measured skeletal muscle glucose uptake in chow-fed and high-fat-fed…”
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Glucose metabolism partially regulates β‐cell function through epigenomic changes by Kim, Yong Kyung, Won, Kyu Chang, Sussel, Lori

“…The β‐cell relies predominantly on glucose utilization to generate adenosine triphosphate, which is crucial for both cell viability and insulin secretion. The…”
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Effects of Diabetes on Motor Recovery After Cerebral Infarct: A Diffusion Tensor Imaging Study by Moon, Jun Sung, Chung, Seung Min, Jang, Sung Ho, Won, Kyu Chang, Chang, Min Cheol

“…Abstract Objective Little is known about the effects of diabetes on motor recovery after cerebral infarct. To address this question, we recruited patients with…”
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