Search Results - "Won, Hong‐Hee"

Association between adiposity and cardiovascular outcomes: an umbrella review and meta-analysis of observational and Mendelian randomization studies by Kim, Min Seo, Kim, Won Jun, Khera, Amit V, Kim, Jong Yeob, Yon, Dong Keon, Lee, Seung Won, Shin, Jae Il, Won, Hong-Hee

“…Abstract Aims The aim of this study was to investigate the causal relationship and evidence of an association between increased adiposity and the risk of…”
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No causal effects of serum urate levels on the risk of chronic kidney disease: A Mendelian randomization study by Jordan, Daniel M, Choi, Hyon K, Verbanck, Marie, Topless, Ruth, Won, Hong-Hee, Nadkarni, Girish, Merriman, Tony R, Do, Ron

“…Studies have shown strong positive associations between serum urate (SU) levels and chronic kidney disease (CKD) risk; however, whether the relation is causal…”
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An atlas of associations between 14 micronutrients and 22 cancer outcomes: Mendelian randomization analyses by Kim, Jong Yeob, Song, Minku, Kim, Min Seo, Natarajan, Pradeep, Do, Ron, Myung, Woojae, Won, Hong-Hee

“…Background Micronutrients, namely vitamins and minerals, are associated with cancer outcomes; however, their reported effects have been inconsistent across…”
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Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia by Khera, Amit V., MD, Won, Hong-Hee, PhD, Peloso, Gina M., PhD, Lawson, Kim S., MS, Bartz, Traci M., MS, Deng, Xuan, MSc, van Leeuwen, Elisabeth M, Natarajan, Pradeep, MD, MMSc, Emdin, Connor A., HBSc, Bick, Alexander G., PhD, Morrison, Alanna C., PhD, Brody, Jennifer A., BA, Gupta, Namrata, PhD, Nomura, Akihiro, MD, Kessler, Thorsten, MD, Duga, Stefano, PhD, Bis, Joshua C., PhD, van Duijn, Cornelia M., PhD, Cupples, L. Adrienne, PhD, Psaty, Bruce, MD, PhD, Rader, Daniel J., MD, Danesh, John, DPhil, Schunkert, Heribert, MD, McPherson, Ruth, MD, Farrall, Martin, MD, Watkins, Hugh, MD, PhD, Lander, Eric, PhD, Wilson, James G., MD, Correa, Adolfo, MD, PhD, Boerwinkle, Eric, PhD, Merlini, Piera Angelica, MD, Ardissino, Diego, MD, Saleheen, Danish, MBBS, PhD, Gabriel, Stacey, PhD, Kathiresan, Sekar, MD

“…Abstract Background Approximately 7% of American adults have severe hypercholesterolemia (untreated low-density lipoprotein [LDL] cholesterol ≥190 mg/dl),…”
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Causal effect of adiposity on the risk of 19 gastrointestinal diseases: a Mendelian randomization study by Kim, Min Seo, Song, Minku, Kim, Soyeon, Kim, Beomsu, Kang, Wonseok, Kim, Jong Yeob, Myung, Woojae, Lee, Inhyeok, Do, Ron, Khera, Amit V., Won, Hong‐Hee

“…Objective Although the association between adiposity and gastrointestinal (GI) diseases has been explored, the causal effects of adiposity on GI diseases are…”
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Association of bariatric surgery with indicated and unintended outcomes: An umbrella review and meta‐analysis for risk–benefit assessment by Kim, Min Seo, Kim, Jong Yeob, Song, Yong Shin, Hong, Seokwon, Won, Hong‐Hee, Kim, Won Jun, Kwon, Yeongkeun, Ha, Jane, Fiedorowicz, Jess G., Solmi, Marco, Shin, Jae Il, Park, Sungsoo, Rosenthal, Raul J.

“…Summary Bariatric surgery can cause numerous functional changes to recipients, some of which are unintended. However, a systematic evaluation of wide‐angled…”
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Machine learning-based prediction model for responses of bDMARDs in patients with rheumatoid arthritis and ankylosing spondylitis by Lee, Seulkee, Kang, Seonyoung, Eun, Yeonghee, Won, Hong-Hee, Kim, Hyungjin, Lee, Jaejoon, Koh, Eun-Mi, Cha, Hoon-Suk

“…Background Few studies on rheumatoid arthritis (RA) have generated machine learning models to predict biologic disease-modifying antirheumatic drugs (bDMARDs)…”
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Integration of observational and causal evidence for the association between adiposity and 17 gastrointestinal outcomes: An umbrella review and meta‐analysis by Kim, Min Seo, Lee, Inhyeok, Natarajan, Pradeep, Do, Ron, Kwon, Yeongkeun, Shin, Jae Il, Solmi, Marco, Kim, Jong Yeob, Won, Hong‐Hee, Park, Sungsoo

“…Summary We systematically reviewed observational and Mendelian randomization (MR) articles that evaluated the association between obesity and 17…”
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Association between air pollution and suicide in South Korea: a nationwide study by Kim, Youngdon, Myung, Woojae, Won, Hong-Hee, Shim, Sanghong, Jeon, Hong Jin, Choi, Junbae, Carroll, Bernard J, Kim, Doh Kwan

“…Suggestive associations of suicide with air pollutant concentrations have been reported. Recognizing regional and temporal variability of pollutant…”
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Polygenic risk for type 2 diabetes, lifestyle, metabolic health, and cardiovascular disease: a prospective UK Biobank study by Yun, Jae-Seung, Jung, Sang-Hyuk, Shivakumar, Manu, Xiao, Brenda, Khera, Amit V, Won, Hong-Hee, Kim, Dokyoon

“…Few studies have examined associations between genetic risk for type 2 diabetes (T2D), lifestyle, clinical risk factors, and cardiovascular disease (CVD). We…”
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Association between genetic risk and adherence to healthy lifestyle for developing age-related hearing loss by Jung, Sang-Hyuk, Lee, Young Chan, Shivakumar, Manu, Kim, Jaeyoung, Yun, Jae-Seung, Park, Woong-Yang, Won, Hong-Hee, Kim, Dokyoon

“…Previous studies have shown that lifestyle/environmental factors could accelerate the development of age-related hearing loss (ARHL). However, there has not…”
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Paraquat prohibition and change in the suicide rate and methods in South Korea by Myung, Woojae, Lee, Geung-Hee, Won, Hong-Hee, Fava, Maurizio, Mischoulon, David, Nyer, Maren, Kim, Doh Kwan, Heo, Jung-Yoon, Jeon, Hong Jin

“…The annual suicide rate in South Korea is the highest among the developed countries. Paraquat is a highly lethal herbicide, commonly used in South Korea as a…”
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Predicting national suicide numbers with social media data by Won, Hong-Hee, Myung, Woojae, Song, Gil-Young, Lee, Won-Hee, Kim, Jong-Won, Carroll, Bernard J, Kim, Doh Kwan

“…Suicide is not only an individual phenomenon, but it is also influenced by social and environmental factors. With the high suicide rate and the abundance of…”
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Polygenic risk score-based phenome-wide association study of head and neck cancer across two large biobanks by Lee, Young Chan, Jung, Sang-Hyuk, Shivakumar, Manu, Cha, Soojin, Park, Woong-Yang, Won, Hong-Hee, Eun, Young-Gyu, Biobank, Penn Medicine, Kim, Dokyoon

“…Numerous observational studies have highlighted associations of genetic predisposition of head and neck squamous cell carcinoma (HNSCC) with diverse risk…”
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Genetic Variants Associated with Supernormal Coronary Arteries by Kim, Beomsu, Lee, Chan Joo, Won, Hong-Hee, Lee, Sang-Hak

“…Aims: Genetic and medical insights from studies on cardioprotective phenotypes aid the development of novel therapeutics. This study identified genetic…”
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Comprehensive characterization of distinct genetic alterations in metastatic breast cancer across various metastatic sites by Cha, Soojin, Lee, Esak, Won, Hong-Hee

“…Metastasis is the major cause of death in breast cancer patients. Although previous large-scale analyses have identified frequently altered genes specific to…”
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A cluster analysis of patients with axial spondyloarthritis using tumour necrosis factor alpha inhibitors based on clinical characteristics by Lee, Seulkee, Kang, Seonyoung, Eun, Yeonghee, Won, Hong-Hee, Kim, Hyungjin, Cha, Hoon-Suk, Koh, Eun-Mi, Lee, Jaejoon

“…This study aimed to classify the distinct group of patients with axial spondyloarthritis (SpA) on tumour necrosis factor alpha inhibitors (TNFi) according to…”
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Moyamoya Disease and Spectrums of RNF213 Vasculopathy by Bang, Oh Young, Chung, Jong-Won, Kim, Dong Hee, Won, Hong-Hee, Yeon, Je Young, Ki, Chang-Seok, Shin, Hyung Jin, Kim, Jong-Soo, Hong, Seung Chyul, Kim, Duk-Kyung, Koizumi, Akio

“…Moyamoya disease (MMD) is a rare cerebrovascular disease characterized by progressive stenosis of large intracranial arteries and a hazy network of basal…”
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hnRNPK-regulated LINC00263 promotes malignant phenotypes through miR-147a/CAPN2 by Lee, Woo Joo, Shin, Chang Hoon, Ji, Haein, Jeong, Seong Dong, Park, Mi-So, Won, Hong-Hee, Pandey, Poonam R., Tsitsipatis, Dimitrios, Gorospe, Myriam, Kim, Hyeon Ho

“…Malignant characteristics of cancers, represented by rapid cell proliferation and high metastatic potential, are a major cause of high cancer-related…”
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Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease by Won, Hong-Hee, Natarajan, Pradeep, Dobbyn, Amanda, Jordan, Daniel M, Roussos, Panos, Lage, Kasper, Raychaudhuri, Soumya, Stahl, Eli, Do, Ron

“…Large genome-wide association studies (GWAS) have identified many genetic loci associated with risk for myocardial infarction (MI) and coronary artery disease…”
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