Search Results - "Womble, Paige D"

Neocortical and cerebellar malformations affect flurothyl-induced seizures in female C57BL/6J mice by Keever, Katherine M, Li, Ying, Womble, Paige D, Sullens, D Gregory, Otazu, Gonzalo H, Lugo, Joaquin N, Ramos, Raddy L

“…Brain malformations cause cognitive disability and seizures in both human and animal models. Highly laminated structures such as the neocortex and cerebellum…”
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Neuronal deletion of phosphatase and tensin homolog in mice results in spatial dysregulation of adult hippocampal neurogenesis by Latchney, Sarah E, Ruiz Lopez, Brayan R, Womble, Paige D, Blandin, Katherine J, Lugo, Joaquin N

“…Adult neurogenesis is a persistent phenomenon in mammals that occurs in select brain structures in both healthy and diseased brains. The tumor suppressor gene,…”
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The effects of ketamine on sexual behavior, anxiety, and locomotion in female rats by Guarraci, Fay A., Gonzalez, Chantal M.F., Lucero, Devon, Womble, Paige D., Abdel-Rahim, Heba, DeVore, Jennie, Kunkel, Marcela Nicole, Quadlander, Emma, Stinnett, Morgan, Boyette-Davis, Jessica

“…The present study characterized the effects of ketamine on sexual behavior and anxiety in female rats. In Experiment 1, female subjects received an injection…”
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Lipopolysaccharide‐induced sickness behavior is not altered in male Fmr1‐deficient mice by Santana‐Coelho, Danielle, Hodges, Samantha L., Quintero, Saul I., Womble, Paige D., Sullens, D. Greg, Narvaiz, David A., Herrera, Rebecca, Sekeres, Melanie J., Lugo, Joaquin N.

“…Objectives Fragile X syndrome is the main monogenetic cause of intellectual disability and autism. Alterations in the immune system are commonly found in these…”
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A Two-Hit Approach Inducing Flurothyl Seizures in Fmr1 Knockout Mice Impacts Anxiety and Repetitive Behaviors by Blandin, Katherine J, Narvaiz, David A, Sullens, Donald Gregory, Womble, Paige D, Hodges, Samantha L, Binder, Matthew S, Faust, Amanda, Nguyen, Phuoc H, Pranske, Zachary J, Lugo, Joaquin N

“…Fragile X Syndrome (FXS) is the leading monogenetic cause of autism spectrum disorder (ASD) and is associated with seizures. We examined the impact of repeated…”
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Brain Malformations in C57BL/6 Mice Affect Seizure Onset by Keever, Katherine M., Li, Ying, Womble, Paige D., Sullens, D. Greg, Lugo, Joaquin N., Ramos, Raddy L.

“…Background Brain malformations are known to cause cognitive delay and seizures in both humans and mice. It has been demonstrated that the neocortex and…”
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NS-Pten knockout mice exhibit sex and hippocampal subregion-specific increases in microglia/macrophage density by Narvaiz, David A., Blandin, Katherine J., Sullens, D. Gregory, Womble, Paige D., Pilcher, Jacob B., O’Neill, Grace, Wiley, Taylor A., Kwok, Eliesse M., Chilukuri, Srikhar V., Lugo, Joaquin N.

“…Seizures induce hippocampal subregion dependent enhancements in microglia/macrophage phagocytosis and cytokine release that may contribute to the development…”
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Agomelatine Is Unable to Attenuate Kainic Acid–Induced Deficits in Early Life Communicative Behavior by Binder, Matthew S., Pranske, Zachary J., Hodges, Samantha L., Womble, Paige D., Kwok, Eliesse M., Quintero, Saul I., Kim, Andrew D., Narvaiz, David A., Lugo, Joaquin N.

“…ABSTRACT Early life seizures are associated with a variety of behavioral comorbidities. Among the most prevalent of these are deficits in communication…”
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Neonatal immune stimulation results in sex‐specific changes in ultrasonic vocalizations but does not affect seizure susceptibility in neonatal mice by Santana‐Coelho, Danielle, Pranske, Zachary J., Nolan, Suzanne O., Hodges, Samantha L., Binder, Matthew S., Womble, Paige D., Narvaiz, David A., Muhammad, Ilyasah, Lugo, Joaquin N.

“…Neuroinflammation during the neonatal period has been linked to disorders such as autism and epilepsy. In this study, we investigated the early life behavioral…”
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Rapamycin, but not minocycline, significantly alters ultrasonic vocalization behavior in C57BL/6J pups in a flurothyl seizure model by Hodges, Samantha L., Womble, Paige D., Kwok, Eliesse M., Darner, Alyssa M., Senger, Savannah S., Binder, Matthew S., Faust, Amanda M., Condon, Siena M., Nolan, Suzanne O., Quintero, Saul I., Lugo, Joaquin N.

“…[Display omitted] •Early-life seizures increased ultrasonic vocalization (USV) quantity in female mice.•Rapamycin reduced USV emission and duration in both…”
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A vitamin D enriched diet attenuates sex-specific behavioral deficits, increases the lifespan, but does not rescue bone abnormalities in a mouse model of cortical dysplasia by Womble, Paige D., Hodges, Samantha L., Nolan, Suzanne O., Binder, Matthew S., Holley, Andrew J., Herrera, Rebecca, Senger, Savannah, Kwok, Eliesse, Narviaz, David A., Faust, Amanda, Hernandez-Zegada, Christian J., Kwon, Ronald Y., Lugo, Joaquin N.

“…[Display omitted] •Vitamin D enriched diet attenuated hypoactivity and rearing in the open-field test.•Vitamin D enriched diet increased percent survival in…”
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A flurothyl-induced seizure does not disrupt hippocampal memory reconsolidation in C57BL/6 J mice by Binder, Matthew S., Prankse, Zachary J., Kim, Andrew D., Hodges, Samantha L., Narvaiz, David A., Womble, Paige D., Lugo, Joaquin N.

“…Memory deficits are a prevalent and pervasive comorbidity of epilepsy that significantly decrease an individual’s quality of life. Numerous studies have…”
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Assessment of the effects of sex, age, and rearing condition on ultrasonic vocalizations elicited by pups during the maternal potentiation paradigm in C57BL/6J mice by Santana‐Coelho, Danielle, Womble, Paige D., Blandin, Katherine J., Pilcher, Jacob B., O'Neill, Grace M., Douglas, Leighton A., Chilukuri, Srikhar V., Tran, Doan L. K., Wiley, Taylor A., Lugo, Joaquin N.

“…Isolation‐induced ultrasonic vocalizations (USVs) are important to elicit parental retrieval. This behavior is critical for the animal's survival and can be…”
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A recreational dose of methylphenidate, but not methamphetamine, decreases anxiety-like behavior in female rats by Boyette-Davis, Jessica A., Rice, Heather R., Shoubaki, Roanne I., Gonzalez, Chantal M.F., Kunkel, Marcela N., Lucero, Devon A., Womble, Paige D., Guarraci, Fay A.

“…•MPH and METH effects on anxiety in females have not been previously studied.•Acute and chronic dosing was used to determine changes in anxiety during the…”
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Multiple Early-Life Seizures Alters Neonatal Communicative Behavior in Fmr1 Knockout Mice by Nguyen, Phuoc H, Narvaiz, David A, Womble, Paige D, Sullens, D Gregory, Binder, Matthew S, Hodges, Samantha L, Kwok, Eliesse, Lugo, Joaquin N

“…Fragile X syndrome (FXS) is the leading monogenic cause of intellectual disability and a significant contributor to Autism Spectrum Disorder. Individuals with…”
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Corrigendum to “The effects of ketamine on sexual behavior, anxiety, and locomotion in female rats” [Pharmacol. Biochem. Behav. 165 (2018) 36–44] by Guarraci, Fay A., Gonzalez, Chantal M.F., Lucero, Devon, Womble, Paige D., Abdel-Rahim, Heba, DeVore, Jennie, Gomez, Alexa, Kunkel, Marcela Nicole, Quadlander, Emma, Stinnett, Morgan, Boyette-Davis, Jessica

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