Search Results - "Wolters, Anouk H G"
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A Kinase Interacting Protein 1 regulates mitochondrial protein levels in energy metabolism and promotes mitochondrial turnover after exercise
Published in Scientific reports (01-11-2023)“…A Kinase Interacting Protein 1 (AKIP1) is a signalling adaptor that promotes mitochondrial respiration and attenuates mitochondrial oxidative stress in…”
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A Kinase Interacting Protein 1 (AKIP1) promotes cardiomyocyte elongation and physiological cardiac remodelling
Published in Scientific reports (10-03-2023)“…A Kinase Interacting Protein 1 (AKIP1) is a signalling adaptor that promotes physiological hypertrophy in vitro. The purpose of this study is to determine if…”
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Large-scale electron microscopy database for human type 1 diabetes
Published in Nature communications (18-05-2020)“…Autoimmune β-cell destruction leads to type 1 diabetes, but the pathophysiological mechanisms remain unclear. To help address this void, we created an…”
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mScarlet3: a brilliant and fast-maturing red fluorescent protein
Published in Nature methods (01-04-2023)“…We report the evolution of mScarlet3, a cysteine-free monomeric red fluorescent protein with fast and complete maturation, as well as record brightness,…”
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Presence of immunogenic alternatively spliced insulin gene product in human pancreatic delta cells
Published in Diabetologia (01-05-2023)“…Aims/hypothesis Transcriptome analyses revealed insulin-gene-derived transcripts in non-beta endocrine islet cells. We studied alternative splicing of human…”
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Guanine quadruplex structures localize to heterochromatin
Published in Nucleic acids research (08-01-2016)“…Increasing amounts of data support a role for guanine quadruplex (G4) DNA and RNA structures in various cellular processes. We stained different organisms with…”
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Connections between Exoproteome Heterogeneity and Virulence in the Oral Pathogen Aggregatibacter actinomycetemcomitans
Published in mSystems (28-06-2022)“…Aggregatibacter actinomycetemcomitans is a Gram-negative bacterial pathogen associated with severe periodontitis and nonoral diseases. Clinical isolates of A…”
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Integrated Array Tomography for 3D Correlative Light and Electron Microscopy
Published in Frontiers in molecular biosciences (19-01-2022)“…Volume electron microscopy (EM) of biological systems has grown exponentially in recent years due to innovative large-scale imaging approaches. As a standalone…”
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Early Upper Aerodigestive Tract Cancer Detection Using Electron Microscopy to Reveal Chromatin Packing Alterations in Buccal Mucosa Cells
Published in Microscopy and microanalysis (01-08-2021)“…A profound characteristic of field cancerization is alterations in chromatin packing. This study aimed to quantify these alterations using electron microscopy…”
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Synergistic antifungal effects of the preservative ammonium propionate and medium chain fatty acids against dormant and germinating conidia, germ tubes and hyphae of Aspergillus chevalieri, a feed spoilage fungus
Published in International journal of food microbiology (16-09-2024)“…In feed, propionic acid is the weak organic acid of choice to prevent growth of spoilage fungi. For safe and easy industrial handling this antifungal agent is…”
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DWORF Extends Life Span in a PLN-R14del Cardiomyopathy Mouse Model by Reducing Abnormal Sarcoplasmic Reticulum Clusters
Published in Circulation research (08-12-2023)“…The p.Arg14del variant of the (phospholamban) gene causes cardiomyopathy, leading to severe heart failure. Calcium handling defects and perinuclear PLN…”
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A novel flatworm-specific gene implicated in reproduction in Macrostomum lignano
Published in Scientific reports (16-02-2018)“…Free-living flatworms, such as the planarian Schmidtea mediterranea , are extensively used as model organisms to study stem cells and regeneration. The…”
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The erythropoietin receptor expressed in skeletal muscle is essential for mitochondrial biogenesis and physiological exercise
Published in Pflügers Archiv (01-08-2021)“…Erythropoietin (EPO) is a haematopoietic hormone that regulates erythropoiesis, but the EPO-receptor (EpoR) is also expressed in non-haematopoietic tissues…”
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Flexible and Extended Linker Domains Support Efficient Targeting of Heh2 to the Inner Nuclear Membrane
Published in Structure (London) (04-02-2020)“…The nuclear pore complex (NPC) is embedded in the nuclear envelope and forms the main gateway to the nuclear interior including the inner nuclear membrane…”
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Large-scale Scanning Transmission Electron Microscopy (Nanotomy) of Healthy and Injured Zebrafish Brain
Published in Journal of visualized experiments (25-05-2016)“…Large-scale 2D electron microscopy (EM), or nanotomy, is the tissue-wide application of nanoscale resolution electron microscopy. Others and we previously…”
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Guanine quadruplex structures localize to heterochromatin
Published in Nucleic acids research (02-06-2017)Get full text
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Selection of polymers for application in scaffolds applicable for human pancreatic islet transplantation
Published in Biomedical materials (Bristol) (13-05-2016)“…The liver is currently the site for transplantation of islets in humans. This is not optimal for islets, but alternative sites in humans are not available…”
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Optimization of negative stage bias potential for faster imaging in large-scale electron microscopy
Published in Journal of structural biology. X (01-01-2021)“…[Display omitted] •The use of a negative bias potential was empirically optimized for tissue imaging with SEM.•Optimized bias potential leads to a factor 20…”
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Large-scale Scanning Transmission Electron Microscopy (Nanotomy) of Healthy and Injured Zebrafish Brain
Published in Journal of visualized experiments (25-05-2016)Get full text
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Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain
Published in Life science alliance (01-07-2023)“…In age-related neurodegenerative diseases, like Alzheimer's and Parkinson's, disease-specific proteins become aggregation-prone and form amyloid-like deposits…”
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