Search Results - "Wolter, Franziska"

Licensing of Orphan Medicinal Products—Use of Real-World Data and Other External Data on Efficacy Aspects in Marketing Authorization Applications Concluded at the European Medicines Agency Between 2019 and 2021 by Naumann-Winter, Frauke, Wolter, Franziska, Hermes, Ulrike, Malikova, Eva, Lilienthal, Nils, Meier, Tania, Kalland, Maria Elisabeth, Magrelli, Armando

“…Background: Reference to so-called real-world data is more often made in marketing authorization applications for medicines intended to diagnose, prevent or…”
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Alterations of the NK cell pool in HIV/HCV co-infection by Kaczmarek, Dominik J, Kokordelis, Pavlos, Krämer, Benjamin, Glässner, Andreas, Wolter, Franziska, Goeser, Felix, Lutz, Philipp, Schwarze-Zander, Carolynne, Boesecke, Christoph, Strassburg, Christian P, Rockstroh, Jürgen K, Spengler, Ulrich, Nattermann, Jacob

“…A relevant proportion of human immunodeficiency virus (HIV) infected patients is co-infected with the hepatitis C virus (HCV). HCV co-infection in HIV-positive…”
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Hypoxia impairs anti-viral activity of natural killer (NK) cells but has little effect on anti-fibrotic NK cell functions in hepatitis C virus infection by Wolter, Franziska, Glässner, Andreas, Krämer, Benjamin, Kokordelis, Pavlos, Finnemann, Claudia, Kaczmarek, Dominik J, Goeser, Felix, Lutz, Philipp, Nischalke, Hans Dieter, Strassburg, Christian P, Spengler, Ulrich, Nattermann, Jacob

“…Graphical abstract…”
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IL-28B Genetic Variants Determine the Extent of Monocyte-Induced Activation of NK Cells in Hepatitis C by Krämer, Benjamin, Finnemann, Claudia, Sastre, Beatriz, Lutz, Philipp, Glässner, Andreas, Wolter, Franziska, Goeser, Felix, Kokordelis, Pavlos, Kaczmarek, Dominik, Nischalke, Hans-Dieter, Strassburg, Christian P, Spengler, Ulrich, Nattermann, Jacob

“…Immuno-genetic studies suggest a functional link between NK cells and λ-IFNs. We recently showed that NK cells are negative for the IFN-λ receptor IFN-λR1 and…”
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Influence of the CXCL1 rs4074 A allele on alcohol induced cirrhosis and HCC in patients of European descent by Nischalke, Hans Dieter, Berger, Cordula, Lutz, Philipp, Langhans, Bettina, Wolter, Franziska, Eisenhardt, Marianne, Krämer, Benjamin, Kokordelis, Pavlos, Glässner, Andreas, Müller, Tobias, Rosendahl, Jonas, Fischer, Janett, Berg, Thomas, Grünhage, Frank, Leifeld, Ludger, Soyka, Michael, Nattermann, Jacob, Sauerbruch, Tilman, Stickel, Felix, Spengler, Ulrich

“…CXCL1 (CXC chemokine-ligand-1) is a ligand for CXC chemokine receptor 2 expressed on hepatic stellate cells (HSC). Thus, CXCL1 might contribute to HSC…”
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TRAIL receptor I (DR4) polymorphisms C626G and A683C are associated with an increased risk for hepatocellular carcinoma (HCC) in HCV-infected patients by Körner, Christian, Riesner, Katarina, Krämer, Benjamin, Eisenhardt, Marianne, Glässner, Andreas, Wolter, Franziska, Berg, Thomas, Müller, Tobias, Sauerbruch, Tilman, Nattermann, Jacob, Spengler, Ulrich, Nischalke, Hans Dieter

“…Tumour surveillance via induction of TRAIL-mediated apoptosis is a key mechanism, how the immune system prevents malignancy. To determine if gene variants in…”
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Impaired CD4+ T cell stimulation of NK cell anti-fibrotic activity may contribute to accelerated liver fibrosis progression in HIV/HCV patients by Glässner, Andreas, Eisenhardt, Marianne, Kokordelis, Pavlos, Krämer, Benjamin, Wolter, Franziska, Nischalke, Hans Dieter, Boesecke, Christoph, Sauerbruch, Tilman, Rockstroh, Jürgen K, Spengler, Ulrich, Nattermann, Jacob

“…Background & Aims HIV/HCV co-infection is characterized by a faster progression to liver fibrosis compared to HCV mono-infection. Epidemiologic studies found…”
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Visual detection of diminutive floral guides in the bumblebee Bombus terrestris and in the honeybee Apis mellifera by Lunau, Klaus, Unseld, Katrin, Wolter, Franziska

“…Many flowers display colour patterns comprising a large peripheral colour area that serves to attract flower visitors from some distance, and a small central,…”
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Assessment of significant benefit for orphan medicinal products by European regulators may support subsequent relative effectiveness assessments by health technology assessment organizations by Vreman, Rick A., de Ruijter, Angela S., Zawada, Anna, Tafuri, Giovanni, Stoyanova-Beninska, Violeta, O’Connor, Daniel, Naumann-Winter, Frauke, Wolter, Franziska, Mantel-Teeuwisse, Aukje K., Leufkens, Hubert G.M., Sidiropoulos, Iordanis, Larsson, Kristina, Goettsch, Wim G.

“…•The Committee for Orphan Medicinal Products performs significant benefit assessments.•Health technology assessment organizations perform relative…”
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An effective interferon‐gamma‐mediated inhibition of hepatitis C virus replication by natural killer cells is associated with spontaneous clearance of acute hepatitis C in human immunodeficiency virus‐positive patients by Kokordelis, Pavlos, Krämer, Benjamin, Körner, Christian, Boesecke, Christoph, Voigt, Esther, Ingiliz, Patrick, Glässner, Andreas, Eisenhardt, Marianne, Wolter, Franziska, Kaczmarek, Dominik, Nischalke, Hans Dieter, Rockstroh, Jürgen K., Spengler, Ulrich, Nattermann, Jacob

“…Hepatitis C virus (HCV) coinfection is an increasing health problem in human immunodeficiency virus‐positive (HIV+) individuals. However, a considerable…”
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The ratio of calprotectin to total protein as a diagnostic and prognostic marker for spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites by Lutz, Philipp, Pfarr, Kenneth, Nischalke, Hans Dieter, Krämer, Benjamin, Goeser, Felix, Glässner, Andreas, Wolter, Franziska, Kokordelis, Pavlos, Nattermann, Jacob, Sauerbruch, Tilman, Hoerauf, Achim, Strassburg, Christian P, Spengler, Ulrich

“…Diagnosis of spontaneous bacterial peritonitis (SBP) is based on a differential ascites leukocyte count which does not provide prognostic information. We…”
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CD3(+)CD56(+) Natural Killer-Like T Cells Display Anti-HCV Activity but Are Functionally Impaired in HIV(+) Patients With Acute Hepatitis C by Kokordelis, Pavlos, Krämer, Benjamin, Boesecke, Christoph, Voigt, Esther, Ingiliz, Patrick, Glässner, Andreas, Wolter, Franziska, Srassburg, Christian P, Spengler, Ulrich, Rockstroh, Jürgen K, Nattermann, Jacob

“…OBJECTIVE:To analyze the role of CD3(+)CD56(+) natural killer (NK)-like T cells in HIV(+) patients with acute hepatitis C. DESIGN:Frequency, phenotype, and…”
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HIV mono-infection is associated with an impaired anti-hepatitis C virus activity of natural killer cells by Goeser, Felix, Glässner, Andreas, Kokordelis, Pavlos, Wolter, Franziska, Lutz, Philipp, Kaczmarek, Dominik J, Schwarze-Zander, Carolynne, Boesecke, Christoph, Strassburg, Christian P, Rockstroh, Jürgen K, Spengler, Ulrich, Krämer, Benjamin, Nattermann, Jacob

“…OBJECTIVE:Hepatitis C virus (HCV) infection in HIV(+) patients is associated with faster liver disease progression compared with HCV mono-infection…”
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HIV mono-infection is associated with an impaired anti-HCV activity of NK cells by Goeser, Felix, Glässner, Andreas, Kokordelis, Pavlos, Wolter, Franziska, Lutz, Philipp, Kaczmarek, Dominik J., Schwarze-Zander, Carolynne, Boesecke, Christoph, Strassburg, Christian P., Rockstroh, Jürgen K., Spengler, Ulrich, Krämer, Benjamin, Nattermann, Jacob

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CD27(+)CD56 super(Bright) natural killer cells may be involved in spontaneous clearance of acute hepatitis C in HIV-positive patients by Eisenhardt, Marianne, Glassner, Andreas, Wolter, Franziska, Kramer, Benjamin, Kokordelis, Pavlos, Nischalke, Hans-Dieter, Boesecke, Christoph, Rockstroh, Jurgen K, Spengler, Ulrich, Nattermann, Jacob

“…Objective: The objective of this study was to analyse the potential role of CD27 in natural killer (NK) cell-mediated control of hepatitis C virus (HCV)…”
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CD27(+)CD56Bright natural killer cells may be involved in spontaneous clearance of acute hepatitis C in HIV-positive patients by EISENHARDT, Marianne, GLÄSSNER, Andreas, WOLTER, Franziska, KRÄMER, Benjamin, KOKORDELIS, Pavlos, NISCHALKE, Hans-Dieter, BOESECKE, Christoph, ROCKSTROH, Jürgen K, SPENGLER, Ulrich, NATTERMANN, Jacob

“…The objective of this study was to analyse the potential role of CD27 in natural killer (NK) cell-mediated control of hepatitis C virus (HCV) infection in…”
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Effect of gabapentin-lactam and gamma-aminobutyric acid/lactam analogs on proliferation and phenotype of ovine mesenchymal stem cells by Sauerbier, Sebastian, Gutwald, Ralf, Wiedmann-Al-Ahmad, Margit, Wolkewitz, Martin, Haberstroh, Jörg, Obermeyer, Julia, Kuenz, Arne, Betz, Helene, Wolter, Franziska, Duttenhoefer, Fabian, Schmelzeisen, Rainer, Nagursky, Heiner, Proksch, Susanne, Al-Ahmad, Ali

“…Classic tissue engineering consists of three components: scaffold, cells, and growth or differentiation factors. Currently, expensive bone morphogenetic…”
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TRAIL receptor I by Krämer, Benjamin, Nischalke, Hans Dieter, Sauerbruch, Tilman, Spengler, Ulrich, Wolter, Franziska, Berg, Thomas, Glässner, Andreas, Müller, Tobias, Körner, Christian, Riesner, Katarina, Eisenhardt, Marianne, Nattermann, Jacob

“…Background Tumour surveillance via induction of TRAIL-mediated apoptosis is a key mechanism, how the immune system prevents malignancy. To determine if gene…”
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TRAIL receptor I in HCV-infected patients by Körner, Christian, Riesner, Katarina, Krämer, Benjamin, Eisenhardt, Marianne, Glässner, Andreas, Wolter, Franziska, Berg, Thomas, Müller, Tobias, Sauerbruch, Tilman, Nattermann, Jacob, Spengler, Ulrich, Nischalke, Hans Dieter

“…Background Tumour surveillance via induction of TRAIL-mediated apoptosis is a key mechanism, how the immune system prevents malignancy. To determine if gene…”
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Influence of the CXCL1 rs4074 A Allele on Alcohol Induced Cirrhosis and HCC in Patients of European Descent: e80848 by Nischalke, Hans Dieter, Berger, Cordula, Lutz, Philipp, Langhans, Bettina, Wolter, Franziska, Eisenhardt, Marianne, Kraemer, Benjamin, Kokordelis, Pavlos, Glaessner, Andreas, Mueller, Tobias

“…Background and Aims CXCL1 (CXC chemokine-ligand-1) is a ligand for CXC chemokine receptor 2 expressed on hepatic stellate cells (HSC). Thus, CXCL1 might…”
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