Search Results - "Wolschek, Markus F"
-
1
The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis
Published in Oncogene (02-10-2003)“…Hepatocytes adopt an invasive and metastatic phenotype caused by the cooperation of transforming growth factor (TGF)-beta and oncogenic Ha-Ras. In the initial…”
Get full text
Journal Article -
2
Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice
Published in Hepatology (Baltimore, Md.) (01-11-2002)“…Systemic tumor-targeted gene delivery is attracting increasing attention as a promising alternative to conventional therapeutical strategies. To be considered…”
Get full text
Journal Article -
3
Mcl-1 Antisense Therapy Chemosensitizes Human Melanoma in a SCID Mouse Xenotransplantation Model
Published in Journal of investigative dermatology (01-06-2003)“…It is well established that high expression of the antiapoptotic Bcl-2 family proteins Bcl-2 and Bcl-xL can significantly contribute to chemoresistance in a…”
Get full text
Journal Article -
4
Mcl-1 is a novel therapeutic target for human sarcoma: Synergistic inhibition of human sarcoma xenotransplants by a combination of Mcl-1 antisense oligonucleotides with low-dose cyclophosphamide
Published in Clinical cancer research (15-06-2004)“…Little is known about the role that Mcl-1, an antiapoptotic Bcl-2 family member, plays in solid tumor biology and susceptibility to anticancer therapy. We…”
Get full text
Journal Article -
5
Tumor-targeted gene delivery of tumor necrosis factor-α induces tumor necrosis and tumor regression without systemic toxicity
Published in Cancer gene therapy (01-08-2002)“…We have recently developed surface-shielded transferrin-polyethylenimine (Tf-PEI)/DNA delivery systems that target reporter gene expression to distant tumors…”
Get full text
Journal Article -
6
Trehalose-6-phosphate synthase A affects citrate accumulation by Aspergillus niger under conditions of high glycolytic flux
Published in FEMS microbiology letters (15-06-1996)“…Accumulation of citric acid by Aspergillus niger depends on a high flux through glycolysis. We have investigated the possibility of control of this flux by…”
Get full text
Journal Article -
7
Mcl-1 Is a Novel Therapeutic Target for Human Sarcoma
Published in Clinical cancer research (15-06-2004)“…Purpose: Little is known about the role that Mcl-1, an antiapoptotic Bcl-2 family member, plays in solid tumor biology and susceptibility to anticancer…”
Get full text
Journal Article -
8
The Filamentous Fungus Aspergillus niger Contains Two “Differentially Regulated” Trehalose-6-phosphate Synthase-encoding Genes, tpsA and tpsB
Published in The Journal of biological chemistry (31-01-1997)“…Two genes encoding trehalose-6-phosphate synthase were cloned from Aspergillus niger. tpsA was cloned using the Saccharomyces cerevisiae GGS1/TPS1 gene as a…”
Get full text
Journal Article -
9
Heterogeneous expression and regulation of CD40 in human hepatocellular carcinoma
Published in European journal of gastroenterology & hepatology (01-02-2003)“…OBJECTIVECD40, a member of the tumour necrosis factor receptor family, plays a major role in adaptive immune responses and contributes to cancer surveillance…”
Get full text
Journal Article -
10
Trehalose-6-phosphate synthase A affects citrate accumulation by Aspergillus niger under conditions of high glycolytic flux
Published in FEMS microbiology letters (01-06-1996)“…Abstract Accumulation of citric acid by Aspergillus niger depends on a high flux through glycolysis. We have investigated the possibility of control of this…”
Get full text
Journal Article -
11
Elevated serum concentrations of the angiogenesis inhibitor endostatin in preeclamptic women
Published in Journal of the Society for Gynecologic Investigation (01-10-2003)“…Changes in serum levels of angiogenic factors such as vascular endothelial growth factor or placental growth factor were associated with preeclampsia. The aim…”
Get more information
Journal Article -
12
The Filamentous Fungus Aspergillus niger Contains Two âDifferentially Regulatedâ Trehalose-6-phosphate Synthase-encoding Genes, tpsA and tpsB
Published in The Journal of biological chemistry (31-01-1997)“…Two genes encoding trehalose-6-phosphate synthase were cloned from Aspergillus niger. tpsA was cloned using the Saccharomyces cerevisiae GGS1/TPS1 gene as a…”
Get full text
Journal Article -
13
Mc1-1 antisense therapy chemosensitizes human melanoma in a SCID mouse xenotransplantation model
Published in Journal of investigative dermatology (2003)Get full text
Journal Article -
14
-
15
Cyclic AMP- and differentiation-dependent regulation of the proximal αHCG gene promoter in term villous trophoblasts
Published in Molecular human reproduction (01-06-1999)“…Although the regulatory mechanisms controlling α and β human chorionic gonadotrophin (HCG) expression have been investigated in choriocarcinoma cell model…”
Get full text
Journal Article -
16
Tumor-targeted gene delivery of tumor necrosis factor-[alpha] induces tumor necrosis and tumor regression without systemic toxicity
Published in Cancer gene therapy (01-08-2002)“…We have recently developed surface-shielded transferrin-polyethylenimine (Tf-PEI)/DNA delivery systems that target reporter gene expression to distant tumors…”
Get full text
Journal Article -
17
In situ detection of protein-DNA interactions in filamentous fungi by in vivo footprinting
Published in Nucleic acids research (15-08-1998)“…The method described here allows the detection of protein—DNA interactions in vivo in filamentous fungi. We outline culture conditions and conditions of in…”
Get full text
Journal Article -
18
Molecular aspects of pregnancy. Cyclic AMP- and differentiation-dependent regulation of the proximal [alpha]HCG gene promoter in term villous trophoblasts
Published in Molecular human reproduction (01-06-1999)“…Although the regulatory mechanisms controlling [alpha] and [beta] human chorionic gonadotrophin (HCG) expression have been investigated in choriocarcinoma cell…”
Get full text
Journal Article