Search Results - "Wolman, A."

Chemical modulation of memory formation in larval zebrafish by Wolman, Marc A, Jain, Roshan A, Liss, Laura, Granato, Michael

“…Whole organism–based small-molecule screens have proven powerful in identifying novel therapeutic chemicals, yet this approach has not been exploited to…”
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A Genome-wide Screen Identifies PAPP-AA-Mediated IGFR Signaling as a Novel Regulator of Habituation Learning by Wolman, Marc A., Jain, Roshan A., Marsden, Kurt C., Bell, Hannah, Skinner, Julianne, Hayer, Katharina E., Hogenesch, John B., Granato, Michael

“…Habituation represents a fundamental form of learning, yet the underlying molecular genetic mechanisms are not well defined. Here we report on a genome-wide…”
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A forward genetic screen identifies Dolk as a regulator of startle magnitude through the potassium channel subunit Kv1.1 by Meserve, Joy H, Nelson, Jessica C, Marsden, Kurt C, Hsu, Jerry, Echeverry, Fabio A, Jain, Roshan A, Wolman, Marc A, Pereda, Alberto E, Granato, Michael

“…The acoustic startle response is an evolutionarily conserved avoidance behavior. Disruptions in startle behavior, particularly startle magnitude, are a…”
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Modulation of cAMP and Ras Signaling Pathways Improves Distinct Behavioral Deficits in a Zebrafish Model of Neurofibromatosis Type 1 by Wolman, Marc A., de Groh, Eric D., McBride, Sean M., Jongens, Thomas A., Granato, Michael, Epstein, Jonathan A.

“…Neurofibromatosis type 1 (NF1) is a common autosomal-dominant disorder associated with attention deficits and learning disabilities. The primary known function…”
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A Cyfip2-Dependent Excitatory Interneuron Pathway Establishes the Innate Startle Threshold by Marsden, Kurt C., Jain, Roshan A., Wolman, Marc A., Echeverry, Fabio A., Nelson, Jessica C., Hayer, Katharina E., Miltenberg, Ben, Pereda, Alberto E., Granato, Michael

“…Sensory experiences dynamically modify whether animals respond to a given stimulus, but it is unclear how innate behavioral thresholds are established. Here,…”
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Pregnancy-associated plasma protein-aa supports hair cell survival by regulating mitochondrial function by Alassaf, Mroj, Daykin, Emily C, Mathiaparanam, Jaffna, Wolman, Marc A

“…To support cell survival, mitochondria must balance energy production with oxidative stress. Inner ear hair cells are particularly vulnerable to oxidative…”
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North Korean Asylum Seekers and Dual Nationality by Wolman, A.

“…In recent years an increasing number of North Korean escapees have attempted to claim asylum outside of South Korea. One of the principal legal questions that…”
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Novel roles for the radial spoke head protein 9 in neural and neurosensory cilia by Sedykh, Irina, TeSlaa, Jessica J., Tatarsky, Rose L., Keller, Abigail N., Toops, Kimberly A., Lakkaraju, Aparna, Nyholm, Molly K., Wolman, Marc A., Grinblat, Yevgenya

“…Cilia are cell surface organelles with key roles in a range of cellular processes, including generation of fluid flow by motile cilia. The axonemes of motile…”
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Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development by Shin, Jimann, Padmanabhan, Arun, de Groh, Eric D, Lee, Jeong-Soo, Haidar, Sam, Dahlberg, Suzanne, Guo, Feng, He, Shuning, Wolman, Marc A, Granato, Michael, Lawson, Nathan D, Wolfe, Scot A, Kim, Seok-Hyung, Solnica-Krezel, Lilianna, Kanki, John P, Ligon, Keith L, Epstein, Jonathan A, Look, A Thomas

“…Neurofibromatosis type 1 (NF1) is a common, dominantly inherited genetic disorder that results from mutations in the neurofibromin 1 (NF1) gene. Affected…”
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State-Dependent Pricing and the General Equilibrium Dynamics of Money and Output by Dotsey, Michael, King, Robert G., Wolman, Alexander L.

“…Economists have long suggested that nominal product prices are changed infrequently because of fixed costs. In such a setting, optimal price adjustment should…”
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A Genome-wide Screen Identifies PAPP-AA-Mediated IGFR Signaling as a Novel Regulator of Habituation Learning by Wolman, Marc A., Jain, Roshan A., Marsden, Kurt C., Bell, Hannah, Skinner, Julianne, Hayer, Katharina E., Hogenesch, John B., Granato, Michael

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Semaphorin3D Regulates Axon Axon Interactions by Modulating Levels of L1 Cell Adhesion Molecule by Wolman, Marc A, Regnery, Ann M, Becker, Thomas, Becker, Catherina G, Halloran, Mary C

“…The decision of a growing axon to selectively fasciculate with and defasciculate from other axons is critical for axon pathfinding and target innervation…”
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Molecular-genetic mapping of zebrafish mutants with variable phenotypic penetrance by Jain, Roshan A, Wolman, Marc A, Schmidt, Lauren A, Burgess, Harold A, Granato, Michael

“…Forward genetic screens in vertebrates are powerful tools to generate models relevant to human diseases, including neuropsychiatric disorders. Variability in…”
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2,4-Dichlorophenoxyacetic acid containing herbicide impairs essential visually guided behaviors of larval fish by Dehnert, Gavin K., Karasov, William H., Wolman, Marc A.

“…•2,4-D exposure reduces survival of zebrafish and perch during larval stages.•2,4-D exposure impairs essential visually guided behaviors of larval zebrafish,…”
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Transient axonal glycoprotein-1 (TAG-1) and laminin-α1 regulate dynamic growth cone behaviors and initial axon direction in vivo by Wolman, Marc A, Sittaramane, Vinoth K, Essner, Jeffrey J, Yost, H Joseph, Chandrasekhar, Anand, Halloran, Mary C

“…BACKGROUND: How axon guidance signals regulate growth cone behavior and guidance decisions in the complex in vivo environment of the central nervous system is…”
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Repulsion and Attraction of Axons by Semaphorin3D Are Mediated by Different Neuropilins In Vivo by Wolman, Marc A, Liu, Yan, Tawarayama, Hiroshi, Shoji, Wataru, Halloran, Mary C

“…Class 3 semaphorins are known to repel and/or sometimes attract axons; however, their role in guiding developing axons in the CNS in vivo is still essentially…”
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In vivo nerve-macrophage interactions following peripheral nerve injury by Rosenberg, Allison F, Wolman, Marc A, Franzini-Armstrong, Clara, Granato, Michael

“…In vertebrates, the peripheral nervous system has retained its regenerative capacity, enabling severed axons to reconnect with their original synaptic targets…”
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An evaluation of scalable application-level multicast built using peer-to-peer overlays by Castro, M., Jones, M. B., Kermarrec, A.-M., Rowstron, A., Theimer, M., Wang, H., Wolman, A.

“…Structured peer-to-peer overlay networks such as CAN, Chord, Pastry, and Tapestry can be used to implement Internet-scale application-level multicast. There…”
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The cell adhesion molecule Tag1, transmembrane protein Stbm/Vangl2, and Lamininα1 exhibit genetic interactions during migration of facial branchiomotor neurons in zebrafish by Sittaramane, Vinoth, Sawant, Anagha, Wolman, Marc A., Maves, Lisa, Halloran, Mary C., Chandrasekhar, Anand

“…Interactions between a neuron and its environment play a major role in neuronal migration. We show here that the cell adhesion molecule Transient Axonal…”
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Protocadherins control the modular assembly of neuronal columns in the zebrafish optic tectum by Cooper, Sharon R, Emond, Michelle R, Duy, Phan Q, Liebau, Brandon G, Wolman, Marc A, Jontes, James D

“…Cell-cell recognition guides the assembly of the vertebrate brain during development. δ-Protocadherins comprise a family of neural adhesion molecules that are…”
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