Search Results - "Wolfson, M F"

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells by Black, Roy A, Rauch, Charles T, Kozlosky, Carl J, Peschon, Jacques J, Slack, Jennifer L, Wolfson, Martin F, Castner, Beverly J, Stocking, Kim L, Reddy, Pranitha, Srinivasan, Subhashini, Nelson, Nicole, Boiani, Norman, Schooley, Kenneth A, Gerhart, Mary, Davis, Raymond, Fitzner, Jeffrey N, Johnson, Richard S, Paxton, Raymond J, March, Carl J, Cerretti, Douglas Pat

“…Mammalian cells proteolytically release (shed) the extracellular domains of many cell-surface proteins. Modification of the cell surface in this way can alter…”
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Crystal Structure of the Catalytic Domain of Human Tumor Necrosis factor-α -converting Enzyme by Maskos, Klaus, Fernandez-Catalan, Carlos, Huber, Robert, Bourenkov, Gleb P., Bartunik, Hans, Ellestad, George A., Reddy, Pranitha, Wolfson, Martin F., Rauch, Charles T., Castner, Beverly J., Davis, Raymond, Howard R. G. Clarke, Petersen, Melissa, Fitzner, Jeffrey N., Cerretti, Douglas Pat, March, Carl J., Paxton, Raymond J., Black, Roy A., Bode, Wolfram

“…Tumor necrosis factor-α (TNFα ) is a cytokine that induces protective inflammatory reactions and kills tumor cells but also causes severe damage when produced…”
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Further evidence for a common mechanism for shedding of cell surface proteins by Müllberg, Jürgen, Rauch, Charles T, Wolfson, Martin F, Castner, Beverly, Fitzner, Jeffrey N, Otten-Evans, Carol, Mohler, Kendall M, Cosman, David, Black, Roy A

“…Pro-TNFα, Steel factor, type II IL-1R and IL-2Rα were expressed in COS-7 cells and the generation of their soluble forms was examined. The release of all four…”
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An Essential Role for Ectodomain Shedding in Mammalian Development by Peschon, Jacques J., Slack, Jennifer L., Reddy, Pranitha, Stocking, Kim L., Sunnarborg, Susan W., Lee, David C., Russell, William E., Castner, Beverly J., Johnson, Richard S., Fitzner, Jeffrey N., Boyce, Rogely W., Nelson, Nicole, Kozlosky, Carl J., Wolfson, Martin F., Rauch, Charles T., Cerretti, Douglas Pat, Paxton, Raymond J., March, Carl J., Black, Roy A.

“…The ectodomains of numerous proteins are released from cells by proteolysis to yield soluble intercellular regulators. The responsible protease, tumor necrosis…”
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Expression and purification of correctly processed, active human TACE catalytic domain in Saccharomyces cerevisiae by Clarke, H R, Wolfson, M F, Rauch, C T, Castner, B J, Huang, C P, Gerhart, M J, Johnson, R S, Cerretti, D P, Paxton, R J, Price, V L, Black, R A

“…Human tumor necrosis factor-alpha (TNF alpha) converting enzyme (TACE) releases soluble TNF alpha from cells. It is a member of the adamalysin family of…”
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Nectin-like Protein 2 Defines a Subset of T-cell Zone Dendritic Cells and Is a Ligand for Class-I-restricted T-cell-associated Molecule by Galibert, Laurent, Diemer, Geoffrey S., Liu, Zhi, Johnson, Richard S., Smith, Jeffrey L., Walzer, Thierry, Comeau, Michael R., Rauch, Charles T., Wolfson, Martin F., Sorensen, Rick A., Van der Vuurst de Vries, Anne-Renée, Branstetter, Daniel G., Koelling, Raymond M., Scholler, John, Fanslow, William C., Baum, Peter R., Derry, Jonathan M., Yan, Wei

“…Dendritic cells (DCs) are a phenotypically and functionally heterogenous population of leukocytes with distinct subsets serving a different set of specialized…”
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Carboxylmethylation affects the proteolysis of myelin basic protein by Staphylococcus aureus V8 proteinase by Sellinger, O Z, Wolfson, M F

“…Bovine myelin basic protein (MBP), charge isoform 1 (C1) was carboxylmethylated by the enzyme D-aspartyl/L-isoaspartyl protein methyltransferase (EC. 2.1.1.77)…”
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