Search Results - "Wolfsberg, Tyra"

A diversity profile of the human skin microbiota by Grice, Elizabeth A, Kong, Heidi H, Renaud, Gabriel, Young, Alice C, Bouffard, Gerard G, Blakesley, Robert W, Wolfsberg, Tyra G, Turner, Maria L, Segre, Julia A

“…The many layers and structures of the skin serve as elaborate hosts to microbes, including a diversity of commensal and pathogenic bacteria that contribute to…”
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The Genome of the Ctenophore Mnemiopsis leidyi and Its Implications for Cell Type Evolution by Ryan, Joseph F., Pang, Kevin, Schnitzler, Christine E., Nguyen, Anh-Dao, Moreland, R. Travis, Simmons, David K., Koch, Bernard J., Francis, Warren R., Havlak, Paul, Smith, Stephen A., Putnam, Nicholas H., Haddock, Steven H. D., Dunn, Casey W., Wolfsberg, Tyra G., Mullikin, James C., Martindale, Mark Q., Baxevanis, Andreas D.

“…An understanding of ctenophore biology is critical for reconstructing events that occurred early in animal evolution. Toward this goal, we have sequenced,…”
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Clinical Genomic Database by Solomon, Benjamin D., Nguyen, Anh-Dao, Bear, Kelly A., Wolfsberg, Tyra G.

“…Technological advances have greatly increased the availability of human genomic sequencing. However, the capacity to analyze genomic data in a clinically…”
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De novo assembly of the goldfish ( Carassius auratus ) genome and the evolution of genes after whole-genome duplication by Chen, Zelin, Omori, Yoshihiro, Koren, Sergey, Shirokiya, Takuya, Kuroda, Takuo, Miyamoto, Atsushi, Wada, Hironori, Fujiyama, Asao, Toyoda, Atsushi, Zhang, Suiyuan, Wolfsberg, Tyra G, Kawakami, Koichi, Phillippy, Adam M, Mullikin, James C, Burgess, Shawn M

“…For over a thousand years, the common goldfish ( ) was raised throughout Asia for food and as an ornamental pet. As a very close relative of the common carp (…”
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Genotype first: Clinical genomics research through a reverse phenotyping approach by Wilczewski, Caralynn M., Obasohan, Justice, Paschall, Justin E., Zhang, Suiyuan, Singh, Sumeeta, Maxwell, George L., Similuk, Morgan, Wolfsberg, Tyra G., Turner, Clesson, Biesecker, Leslie G., Katz, Alexander E.

“…Although genomic research has predominantly relied on phenotypic ascertainment of individuals affected with heritable disease, the falling costs of sequencing…”
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MLV integration site selection is driven by strong enhancers and active promoters by LaFave, Matthew C, Varshney, Gaurav K, Gildea, Derek E, Wolfsberg, Tyra G, Baxevanis, Andreas D, Burgess, Shawn M

“…Retroviruses integrate into the host genome in patterns specific to each virus. Understanding the causes of these patterns can provide insight into viral…”
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A chromosome-scale epigenetic map of the Hydra genome reveals conserved regulators of cell state by Cazet, Jack F, Siebert, Stefan, Little, Hannah Morris, Bertemes, Philip, Primack, Abby S, Ladurner, Peter, Achrainer, Matthias, Fredriksen, Mark T, Moreland, R Travis, Singh, Sumeeta, Zhang, Suiyuan, Wolfsberg, Tyra G, Schnitzler, Christine E, Baxevanis, Andreas D, Simakov, Oleg, Hobmayer, Bert, Juliano, Celina E

“…The epithelial and interstitial stem cells of the freshwater polyp are the best-characterized stem cell systems in any cnidarian, providing valuable insight…”
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A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies by Nalls, Michael A, Duran, Raquel, Lopez, Grisel, Kurzawa-Akanbi, Marzena, McKeith, Ian G, Chinnery, Patrick F, Morris, Christopher M, Theuns, Jessie, Crosiers, David, Cras, Patrick, Engelborghs, Sebastiaan, De Deyn, Peter Paul, Van Broeckhoven, Christine, Mann, David M A, Snowden, Julie, Pickering-Brown, Stuart, Halliwell, Nicola, Davidson, Yvonne, Gibbons, Linda, Harris, Jenny, Sheerin, Una-Marie, Bras, Jose, Hardy, John, Clark, Lorraine, Marder, Karen, Honig, Lawrence S, Berg, Daniela, Maetzler, Walter, Brockmann, Kathrin, Gasser, Thomas, Novellino, Fabiana, Quattrone, Aldo, Annesi, Grazia, De Marco, Elvira Valeria, Rogaeva, Ekaterina, Masellis, Mario, Black, Sandra E, Bilbao, Juan M, Foroud, Tatiana, Ghetti, Bernardino, Nichols, William C, Pankratz, Nathan, Halliday, Glenda, Lesage, Suzanne, Klebe, Stephan, Durr, Alexandra, Duyckaerts, Charles, Brice, Alexis, Giasson, Benoit I, Trojanowski, John Q, Hurtig, Howard I, Tayebi, Nahid, Landazabal, Claudia, Knight, Melanie A, Keller, Margaux, Singleton, Andrew B, Wolfsberg, Tyra G, Sidransky, Ellen

“…While mutations in glucocerebrosidase (GBA1) are associated with an increased risk for Parkinson disease (PD), it is important to establish whether such…”
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Primary oxidative phosphorylation defects lead to perturbations in the human B cell repertoire by Gordon-Lipkin, Eliza M, Banerjee, Payal, Franco, Jose Luis Marin, Tarasenko, Tatiana, Kruk, Shannon, Thompson, Elizabeth, Gildea, Derek E, Zhang, Suiyuan, Wolfsberg, Tyra G, Flegel, Willy A, McGuire, Peter J

“…The majority of studies on oxidative phosphorylation in immune cells have been performed in mouse models, necessitating human translation. To understand the…”
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AniProtDB: A Collection of Consistently Generated Metazoan Proteomes for Comparative Genomics Studies by Barreira, Sofia N, Nguyen, Anh-Dao, Fredriksen, Mark T, Wolfsberg, Tyra G, Moreland, R Travis, Baxevanis, Andreas D

“…Abstract To address the void in the availability of high-quality proteomic data traversing the animal tree, we have implemented a pipeline for generating de…”
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A large-scale zebrafish gene knockout resource for the genome-wide study of gene function by Varshney, Gaurav K, Lu, Jing, Gildea, Derek E, Huang, Haigen, Pei, Wuhong, Yang, Zhongan, Huang, Sunny C, Schoenfeld, David, Pho, Nam H, Casero, David, Hirase, Takashi, Mosbrook-Davis, Deborah, Zhang, Suiyuan, Jao, Li-En, Zhang, Bo, Woods, Ian G, Zimmerman, Steven, Schier, Alexander F, Wolfsberg, Tyra G, Pellegrini, Matteo, Burgess, Shawn M, Lin, Shuo

“…With the completion of the zebrafish genome sequencing project, it becomes possible to analyze the function of zebrafish genes in a systematic way. The first…”
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Identification of neural crest and glial enhancers at the mouse Sox10 locus through transgenesis in zebrafish by Antonellis, Anthony, Huynh, Jimmy L, Lee-Lin, Shih-Queen, Vinton, Ryan M, Renaud, Gabriel, Loftus, Stacie K, Elliot, Gene, Wolfsberg, Tyra G, Green, Eric D, McCallion, Andrew S, Pavan, William J

“…Sox10 is a dynamically regulated transcription factor gene that is essential for the development of neural crest-derived and oligodendroglial populations…”
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The genome of the colonial hydroid Hydractinia reveals that their stem cells use a toolkit of evolutionarily shared genes with all animals by Schnitzler, Christine E, Chang, E Sally, Waletich, Justin, Quiroga-Artigas, Gonzalo, Wong, Wai Yee, Nguyen, Anh-Dao, Barreira, Sofia N, Doonan, Liam B, Gonzalez, Paul, Koren, Sergey, Gahan, James M, Sanders, Steven M, Bradshaw, Brian, DuBuc, Timothy Q, Febrimarsa, de Jong, Danielle, Nawrocki, Eric P, Larson, Alexandra, Klasfeld, Samantha, Gornik, Sebastian G, Moreland, R Travis, Wolfsberg, Tyra G, Phillippy, Adam M, Mullikin, James C, Simakov, Oleg, Cartwright, Paulyn, Nicotra, Matthew, Frank, Uri, Baxevanis, Andreas D

“…is a colonial marine hydroid that shows remarkable biological properties, including the capacity to regenerate its entire body throughout its lifetime, a…”
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Predisposition to cancer caused by genetic and functional defects of mammalian Atad5 by Bell, Daphne W, Sikdar, Nilabja, Lee, Kyoo-Young, Price, Jessica C, Chatterjee, Raghunath, Park, Hee-Dong, Fox, Jennifer, Ishiai, Masamichi, Rudd, Meghan L, Pollock, Lana M, Fogoros, Sarah K, Mohamed, Hassan, Hanigan, Christin L, Zhang, Suiyuan, Cruz, Pedro, Renaud, Gabriel, Hansen, Nancy F, Cherukuri, Praveen F, Borate, Bhavesh, McManus, Kirk J, Stoepel, Jan, Sipahimalani, Payal, Godwin, Andrew K, Sgroi, Dennis C, Merino, Maria J, Elliot, Gene, Elkahloun, Abdel, Vinson, Charles, Takata, Minoru, Mullikin, James C, Wolfsberg, Tyra G, Hieter, Philip, Lim, Dae-Sik, Myung, Kyungjae

“…ATAD5, the human ortholog of yeast Elg1, plays a role in PCNA deubiquitination. Since PCNA modification is important to regulate DNA damage bypass, ATAD5 may…”
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DNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays by Crawford, Gregory E, Davis, Sean, Scacheri, Peter C, Renaud, Gabriel, Halawi, Mohamad J, Erdos, Michael R, Green, Roland, Meltzer, Paul S, Wolfsberg, Tyra G, Collins, Francis S

“…Mapping DNase I hypersensitive sites is an accurate method of identifying the location of gene regulatory elements, including promoters, enhancers, silencers…”
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Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS) by Crawford, Gregory E, Holt, Ingeborg E, Whittle, James, Webb, Bryn D, Tai, Denise, Davis, Sean, Margulies, Elliott H, Chen, YiDong, Bernat, John A, Ginsburg, David, Zhou, Daixing, Luo, Shujun, Vasicek, Thomas J, Daly, Mark J, Wolfsberg, Tyra G, Collins, Francis S

“…A major goal in genomics is to understand how genes are regulated in different tissues, stages of development, diseases, and species. Mapping DNase I…”
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The stat3/socs3a Pathway Is a Key Regulator of Hair Cell Regeneration in Zebrafish stat3/socs3a Pathway: Regulator of Hair Cell Regeneration by Liang, Jin, Wang, Dongmei, Renaud, Gabriel, Wolfsberg, Tyra G, Wilson, Alexander F, Burgess, Shawn M

“…All nonmammalian vertebrates studied can regenerate inner ear mechanosensory receptors (i.e., hair cells) (Corwin and Cotanche, 1988; Lombarte et al., 1993;…”
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Short Interfering RNAs Can Induce Unexpected and Divergent Changes in the Levels of Untargeted Proteins in Mammalian Cells by Scacheri, Peter C., Rozenblatt-Rosen, Orit, Caplen, Natasha J., Wolfsberg, Tyra G., Umayam, Lowell, Lee, Jeffrey C., Hughes, Christina M., Shanmugam, Kalai Selvi, Bhattacharjee, Arindam, Meyerson, Matthew, Collins, Francis S., Vogelstein, Bert

“…RNA interference (RNAi) mediated by short interfering RNAs (siRNAs) is a widely used method to analyze gene function. To use RNAi knockdown accurately to infer…”
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Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells by Hematti, Peiman, Hong, Bum-Kee, Ferguson, Cole, Adler, Rima, Hanawa, Hideki, Sellers, Stephanie, Holt, Ingeborg E, Eckfeldt, Craig E, Sharma, Yugal, Schmidt, Manfred, von Kalle, Christof, Persons, Derek A, Billings, Eric M, Verfaillie, Catherine M, Nienhuis, Arthur W, Wolfsberg, Tyra G, Dunbar, Cynthia E, Calmels, Boris

“…Murine leukemia virus (MLV)-derived vectors are widely used for hematopoietic stem cell (HSC) gene transfer, but lentiviral vectors such as the simian…”
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Low incidence of hepatocellular carcinoma in mice and cats treated with systemic adeno-associated viral vectors by Ferla, Rita, Alliegro, Marialuisa, Dell’Anno, Margherita, Nusco, Edoardo, Cullen, John M., Smith, Stephanie N., Wolfsberg, Tyra G., O’Donnell, Patricia, Wang, Ping, Nguyen, Anh-Dao, Chandler, Randy J., Chen, Zelin, Burgess, Shawn M., Vite, Charles H., Haskins, Mark E., Venditti, Charles P., Auricchio, Alberto

“…Adeno-associated viral (AAV) vectors have emerged as the preferred platform for in vivo gene transfer because of their combined efficacy and safety. However,…”
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