Search Results - "Wolfs, Esther"
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Optimization of whole slide imaging scan settings for computer vision using human lung cancer tissue
Published in PloS one (09-09-2024)“…Digital pathology has become increasingly popular for research and clinical applications. Using high-quality microscopes to produce Whole Slide Images of tumor…”
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The Effect of Leukocyte- and Platelet-Rich Fibrin on Central and Peripheral Nervous System Neurons—Implications for Biomaterial Applicability
Published in International journal of molecular sciences (01-09-2023)“…Leukocyte- and Platelet-Rich Fibrin (L-PRF) is a second-generation platelet concentrate that is prepared directly from the patient’s own blood. It is widely…”
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Adult Neurogenesis in the Subventricular Zone and Its Regulation After Ischemic Stroke: Implications for Therapeutic Approaches
Published in Translational stroke research (01-02-2020)“…Adult neurogenesis in the subventricular zone is a topic of intense research, since it has vast implications for the fundamental understanding of the…”
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Stem Cell-Based Therapies for Ischemic Stroke: Preclinical Results and the Potential of Imaging-Assisted Evaluation of Donor Cell Fate and Mechanisms of Brain Regeneration
Published in Medicinal research reviews (01-11-2016)“…Stroke is the second most common cause of death and is a major cause of permanent disability. Given the current demographic trend of an ageing population and…”
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The Angiogenic Potential of DPSCs and SCAPs in an In Vivo Model of Dental Pulp Regeneration
Published in Stem Cells International (01-01-2017)“…Adequate vascularization, a restricting factor for the survival of engineered tissues, is often promoted by the addition of stem cells or the appropriate…”
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The Influence of Lysosomal Stress on Dental Pulp Stem Cell-Derived Schwann Cells
Published in Biomolecules (Basel, Switzerland) (01-04-2024)“…Dysregulation of the endo-lysosomal-autophagy pathway has been identified as a critical factor in the pathology of various demyelinating neurodegenerative…”
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SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells
Published in Stem cell reports (13-02-2018)“…Scarce access to primary samples and lack of efficient protocols to generate oligodendrocytes (OLs) from human pluripotent stem cells (hPSCs) are hampering our…”
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Pyridoxamine Attenuates Doxorubicin-Induced Cardiomyopathy without Affecting Its Antitumor Effect on Rat Mammary Tumor Cells
Published in Cells (Basel, Switzerland) (01-01-2024)“…Doxorubicin (DOX) is commonly used in cancer treatment but associated with cardiotoxicity. Pyridoxamine (PM), a vitamin B6 derivative, could be a…”
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Advances and challenges in modeling inherited peripheral neuropathies using iPSCs
Published in Experimental & molecular medicine (01-06-2024)“…Inherited peripheral neuropathies (IPNs) are a group of diseases associated with mutations in various genes with fundamental roles in the development and…”
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Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
Published in Stem cell reports (10-11-2015)“…Tools for rapid and efficient transgenesis in “safe harbor” loci in an isogenic context remain important to exploit the possibilities of human pluripotent stem…”
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Angiogenic Capacity of Periodontal Ligament Stem Cells Pretreated with Deferoxamine and/or Fibroblast Growth Factor-2
Published in PloS one (09-12-2016)“…Periodontal ligament stem cells (PDLSCs) represent a good source of multipotent cells for cell-based therapies in regenerative medicine. The success rate of…”
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The Neurovascular Properties of Dental Stem Cells and Their Importance in Dental Tissue Engineering
Published in Stem cells international (01-01-2016)“…Within the field of tissue engineering, natural tissues are reconstructed by combining growth factors, stem cells, and different biomaterials to serve as a…”
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Optimization of multimodal imaging of mesenchymal stem cells using the human sodium iodide symporter for PET and Cerenkov luminescence imaging
Published in PloS one (01-04-2014)“…The use of stably integrated reporter gene imaging provides a manner to monitor the in vivo fate of engrafted cells over time in a non-invasive manner. Here,…”
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Preconditioning of Human Dental Pulp Stem Cells with Leukocyte- and Platelet-Rich Fibrin-Derived Factors Does Not Enhance Their Neuroregenerative Effect
Published in Stem cells international (01-01-2019)“…Pathologies of the central nervous system are characterized by loss of brain tissue and neuronal function which cannot be adequately restored by endogenous…”
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Pyridoxamine Limits Cardiac Dysfunction in a Rat Model of Doxorubicin-Induced Cardiotoxicity
Published in Antioxidants (01-01-2024)“…The use of doxorubicin (DOX) chemotherapy is restricted due to dose-dependent cardiotoxicity. Pyridoxamine (PM) is a vitamin B6 derivative with favorable…”
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Extracellular vesicle‐associated cholesterol supports the regenerative functions of macrophages in the brain
Published in Journal of extracellular vesicles (01-12-2023)“…Macrophages play major roles in the pathophysiology of various neurological disorders, being involved in seemingly opposing processes such as lesion…”
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Dental Tissue and Stem Cells Revisited: New Insights From the Expression of Fibroblast Activation Protein-Alpha
Published in Frontiers in cell and developmental biology (21-01-2020)“…Fibroblast activation protein-α (FAPα) is a membrane protein with dipeptidyl-peptidase and type I collagenase activity and is expressed during fetal growth. At…”
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Sodium Iodide Symporter PET and BLI Noninvasively Reveal Mesoangioblast Survival in Dystrophic Mice
Published in Stem cell reports (08-12-2015)“…Muscular dystrophies are a heterogeneous group of myopathies, characterized by muscle weakness and degeneration, without curative treatment. Mesoangioblasts…”
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Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
Published in Stem cell reports (13-02-2018)Get full text
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Abstract 15199: Pyridoxamine Limits Mitochondria-Dependent Ferroptosis in a Rat Model of Doxorubicin-Induced Cardiotoxicity
Published in Circulation (New York, N.Y.) (07-11-2023)“…Abstract only Background: The use of doxorubicin (DOX) chemotherapy is limited by cardiotoxicity characterized by mitochondrial iron accumulation and…”
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